Phase 3 Hypertension Clinical Trials
76 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 76 trials
Recruiting
Phase 3
A Phase 3 Study to Evaluate the Safety and Efficacy L606 in Participants With PH-ILD
Pulmonary Hypertension Due to Lung Disease (Disorder)
Liquidia Technologies, Inc.344 enrolled6 locationsNCT07285655
Recruiting
Phase 3
A Clinical Study of Sotatercept (MK-7962) in People With Pulmonary Arterial Hypertension (MK-7962-038)
Pulmonary Arterial Hypertension
Merck Sharp & Dohme LLC815 enrolled119 locationsNCT07218029
Recruiting
Phase 3
Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy
Pre-EclampsiaIntrauterine Growth RestrictionAspirin+3 more
Centre Hospitalier Intercommunal Creteil500 enrolled20 locationsNCT04356326
Recruiting
Phase 3
Zilebesiran in Patients With Hypertension Not Adequately Controlled and With Either Established Cardiovascular Disease or High Risk for Cardiovascular Disease
HypertensionHigh Risk Cardiovascular DiseaseHigh Cardiovascular Risk
Alnylam Pharmaceuticals11,000 enrolled856 locationsNCT07181109
Recruiting
Phase 3
EASi-PROTKT™ - A Study to Test Vicadrostat (BI 690517) Taken Together With Empagliflozin in People With Type 2 Diabetes, High Blood Pressure, and Cardiovascular Disease
Cardiovascular DiseasesHypertensionDiabetes Mellitus, Type 2
Boehringer Ingelheim11,800 enrolled1155 locationsNCT07064473
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safety of Once Daily Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Insmed Incorporated344 enrolled2 locationsNCT07481981
Recruiting
Phase 3
Doxycycline Host-directed Therapy to Improve Lung Function and Decrease Tissue Destruction in Pulmonary Tuberculosis
Acute Coronary SyndromeTuberculosisPulmonary Hypertension (Diagnosis)
National University Hospital, Singapore150 enrolled6 locationsNCT05473520
Recruiting
Phase 3
A Study Providing Treatment Access in Participants With Pulmonary Hypertension Completing a Parent Study and Having no Other Option
Hypertension, Pulmonary
Actelion280 enrolled45 locationsNCT05179876
Recruiting
Phase 3
Phase III Study of HRS-7535 for Hypertension With Overweight or Obesity
Hypertension With Overweight or Obesity
Shandong Suncadia Medicine Co., Ltd.648 enrolled2 locationsNCT07528027
Recruiting
Phase 3
A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure
Chronic Kidney Disease and Hypertension
AstraZeneca5,000 enrolled761 locationsNCT06742723
Recruiting
Phase 3
Efficacy and Safety Study of Treprostinil Palmitil Inhalation Powder (TPIP) in Participants With Pulmonary Hypertension Associated With Interstitial Lung Disease (PH-ILD)
Interstitial Lung DiseasePulmonary Hypertension
Insmed Incorporated344 enrolled109 locationsNCT07179380
Recruiting
Phase 3
COMMODITIES Trial: Initial Dual Oral Therapy vs Monotherapy in PAH With Cardiovascular Comorbidities
ComorbiditiesCardiovascular Disease (CVD)Pulmonary Arterial Hypertension PAH
Assistance Publique - Hôpitaux de Paris186 enrolled1 locationNCT07245680
Recruiting
Phase 3
A Master Protocol for Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight: (ATTAIN-Hypertension Screening)
Hypertension
Eli Lilly and Company974 enrolled100 locationsNCT06948422
Recruiting
Phase 3
An Adaptive Program of IKT-001 in Pulmonary Arterial Hypertension (PAH)
Pulmonary Arterial Hypertension
Inhibikase Therapeutics486 enrolled2 locationsNCT07365332
Recruiting
Phase 3
Clinical Trial to Evaluate the Efficacy and Safety of Monotherapy Group of HL1113R1 or HL1113R2 Versus HL1113 (Fixed Dose Combination) in Patients With Essential Hypertension and Type II Diabetes Mellitus
HypertensionDiabete Type 2
Hanlim Pharm. Co., Ltd.228 enrolled1 locationNCT07552389
Recruiting
Phase 3
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL1
HypertensionOverweight or Obesity
Eli Lilly and Company487 enrolled99 locationsNCT06948435
Recruiting
Phase 3
A Master Protocol Study of Orforglipron (LY3502970) in Participants With Hypertension and Obesity or Overweight (ATTAIN-Hypertension) GZL2
Hypertension
Eli Lilly and Company487 enrolled99 locationsNCT06952530
Recruiting
Phase 2Phase 3
PRECISION-BP: Precision Chronopharamacotherapy Targeting NP-RAAS-BP Rhythm Axis
ObesityCardiovascular DiseasesHypertension+3 more
University of Alabama at Birmingham160 enrolled1 locationNCT04971720
Recruiting
Phase 3
Intranasal Dexmedetomidine on Blood Pressure in Elderly Hypertensive Patients Undergoing Cataract Surgery
HypertensionCataract
Suez Canal University126 enrolled1 locationNCT07080229
Recruiting
Phase 2Phase 3
Study of QLS-111-FDC in Open-Angle Glaucoma or Ocular Hypertension
OAG - Open-Angle GlaucomaOHT - Ocular Hypertension
Qlaris Bio, Inc.60 enrolled1 locationNCT07354516