Hypoparathyroidism Clinical Trials

27 recruitingLast updated: June 18, 2026

There are 27 actively recruiting hypoparathyroidism clinical trials across 14 countries. Studies span Not Applicable, Phase 2, Phase 1, Phase 3, Early Phase 1, Phase 4. Top locations include Le Kremlin-Bicêtre, France, Lyon, France, Beijing, China. Updated daily from ClinicalTrials.gov.


Hypoparathyroidism Trials at a Glance

27 actively recruiting trials for hypoparathyroidism are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Le Kremlin-Bicêtre, Lyon, and Beijing. Lead sponsors running hypoparathyroidism studies include Peking Union Medical College Hospital, Ascendis Pharma A/S, and Tartu University Hospital.

Browse hypoparathyroidism trials by phase

Treatments under study

About Hypoparathyroidism Clinical Trials

Looking for clinical trials for Hypoparathyroidism? There are currently 17 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Hypoparathyroidism trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Hypoparathyroidism clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 27 trials

Recruiting
Early Phase 1

Efficacy and Safety of XH02 for the Treatment of Hypoparathyroidism

Hypoparathyroidism
Peking Union Medical College Hospital6 enrolled1 locationNCT07197450
Recruiting
Phase 2

A Cohort Study on the Safety and Efficacy of XH-02 in Treating Hypoparathyroidism

Hypoparathyroidism
Peking Union Medical College Hospital60 enrolled1 locationNCT07540286
Recruiting

Natural History Study of Parathyroid Disorders

Multiple Endocrine Neoplasia Type 1Primary HyperparathyroidismParathyroid Cancer+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)3,000 enrolled1 locationNCT04969926
Recruiting

Routine Validation and Reproducibility Testing of Laboratory Assays and Research Techniques Used for Endocrine, Cardiometabolic, and Musculoskeletal Disorder Research (VALD)

Heart FailureSarcopeniaOsteoporosis+11 more
Bettina Mittendorfer100 enrolled1 locationNCT07083557
Recruiting

Risk Factors for Hypoparathyroidism Following Thyroidectomy

Post-Surgical Hypoparathyroidism
Tartu University Hospital300 enrolled2 locationsNCT07582562
Recruiting
Not Applicable

Calcium Replacement Therapy in Postoperative Hypoparathyroidism

Post-Thyroidectomy Hypoparathyroidism Treatment
Tartu University Hospital50 enrolled2 locationsNCT07577570
Recruiting
Phase 3

A Phase 3 Randomized Clinical Trial to Investigate the Safety and Efficacy of Palopegteriparatide at Doses Greater Than 30 μg/Day in Adult Participants With Hypoparathyroidism

HypoparathyroidismEndocrine System DiseasesParathyroid Diseases
Ascendis Pharma Bone Diseases A/S36 enrolled3 locationsNCT07081997
Recruiting

A Study to Assess the Amount of Palopegteriparatide in Breast Milk of Lactating Females Requiring YORVIPATH® (Palopegteriparatide)

Hypoparathyroidism
Ascendis Pharma A/S10 enrolled1 locationNCT07264634
Recruiting
Phase 1Phase 2

Efficacy and Safety of Subcutaneous Injection of XH-02 in the Treatment of Adult Hypoparathyroidism

Hypoparathyroidism
Peking Union Medical College Hospital15 enrolled1 locationNCT07530705
Recruiting
Not Applicable

PRESS -PAR: Early Detection and PREvention of Symptomatic postSurgical hypoPARathyroidism After Thyroid Surgery"

Hypoparathyroidism Post-surgicalPostoperative HypoparathyroidismPostsurgical Hypoparathyroidism
Nicolas Schlegel336 enrolled1 locationNCT07491601
Recruiting

A Global Pregnancy Registry to Assess Maternal, Fetal, and Infant Outcomes Following Exposure to YORVIPATH® (Palopegteriparatide) During Pregnancy and Breastfeeding

Hypoparathyroidism
Ascendis Pharma A/S50 enrolled1 locationNCT07345494
Recruiting
Phase 1Phase 2

Parathyroid Allotransplant for Treatment of Hypoparathyroidism

HypoparathyroidismHypoparathyroidism Post-surgicalHypoparathyroidism Postprocedural
Peter Stock3 enrolled1 locationNCT06961071
Recruiting
Not Applicable

Comparing PTeye-assisted Versus Conventional Total Thyroidectomy

Total ThyroidectomyHypocalcemiaHypoparathyroidism Post-surgical+1 more
The University of Hong Kong210 enrolled1 locationNCT07416149
Recruiting

IDMet (RaDiCo Cohort) (RaDiCo-IDMet)

Beckwith-Wiedemann SyndromePrader-Willi SyndromePseudohypoparathyroidism+6 more
Institut National de la Santé Et de la Recherche Médicale, France2,000 enrolled20 locationsNCT05945576
Recruiting

Hypoparathyroidism Natural History Study

Hypoparathyroidism
Columbia University106 enrolled1 locationNCT05793853
Recruiting
Phase 2

Evaluating the Safety and Efficacy of AMOR-1 as a Treatment for Hypocalcemia Associated With Hypoparathyroidism in Adults

Hypoparathyroidism
Amorphical Ltd.81 enrolled8 locationsNCT06547151
Recruiting
Not Applicable

PTeye vs Surgeons Eyes in Intraoperative Identification and Functional Preservation of Parathyroid Glands During Thyroid Surgery: A Parallel Randomized Controlled Clinical Trial.

Thyroid surgeryHypoparathyroidism Post-surgicalParathyroid Dysfunction
Marcin Barczynski154 enrolled1 locationNCT06765941
Recruiting
Phase 4

Treatment With Indapamide in Patients With Post-Surgical Hypoparathyroidism

Hypoparathyroidism Post-surgical
Lars Rejnmark24 enrolled1 locationNCT07034677
Recruiting

A Registry on comparing the older and and newer treatment methods for Hypoparathyroidism in Greece

Hypoparathyroidism
Rodis D Paparodis - Hellenic Endocrine Network500 enrolled1 locationACTRN12625000514404
Recruiting
Not Applicable

Albright Hereditary Osteodystrophy: Natural History, Growth, and Cognitive/Behavioral Assessments

Pseudohypoparathyroidism Type 1AAlbright Hereditary OsteodystrophyPseudopseudohypoparathyroidism
Connecticut Children's Medical Center600 enrolled1 locationNCT00209235