Infection Clinical Trials in Boston, Massachusetts

36 recruitingBoston, Massachusetts

Showing 120 of 36 trials

Recruiting
Phase 2

A Study Evaluating the Efficacy and Safety of ALG-000184 Compared With Tenofovir Disoproxil Fumarate in Untreated HBeAg-Positive and HBeAg- Negative Adult Subjects With Chronic Hepatitis B (B-SUPREME)

Chronic Hepatitis B Infection
Aligos Therapeutics200 enrolled58 locationsNCT06963710
Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 3

A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose

RSV Infection
Pfizer550 enrolled93 locationsNCT06866405
Recruiting
Phase 2

A Clinical Trial of Combination HIV-Specific Broadly Neutralizing Monoclonal Antibodies Combined With ART Initiation During Acute HIV Infection to Induce HIV Remission

Acute HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)48 enrolled36 locationsNCT05719441
Recruiting
Phase 3

A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1

HIV Infections
ViiV Healthcare332 enrolled89 locationsNCT06694805
Recruiting

Biomarkers in Infection

SepsisInflammationInfection
Beth Israel Deaconess Medical Center4,200 enrolled2 locationsNCT02545478
Recruiting
Phase 1

Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706

HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled7 locationsNCT06665646
Recruiting
Phase 2

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

Clostridioides Difficile Infection
AstraZeneca230 enrolled113 locationsNCT07285213
Recruiting

Pharmacokinetics, Pharmacodynamics, and Safety Profile of Understudied Drugs Administered to Children Per Standard of Care (POPS)

Heart FailurePainInsomnia+22 more
Duke University5,000 enrolled51 locationsNCT04278404
Recruiting
Not Applicable

Home Hospital for Suddenly Ill Adults

Heart FailureAsthmaChronic Kidney Diseases+6 more
Brigham and Women's Hospital3,000 enrolled2 locationsNCT03524222
Recruiting
Phase 1Phase 2

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Not Applicable

Trial to Reduce Antimicrobial Use in Nursing Home Residents With Alzheimer's Disease and Other Dementias 2.0

DementiaInfectionsAlzheimer Disease
Hebrew SeniorLife750 enrolled1 locationNCT05950607
Recruiting
Phase 2

Improving Coronary Vascular Health in Women

Metabolic DiseaseHIV-1-infectionCoronary Microvascular Dysfunction
Massachusetts General Hospital80 enrolled1 locationNCT06843902
Recruiting

Multi-Center Molecular Diagnosis and Host Response of Respiratory Viral Infections in Pediatric Transplant Recipients

Solid Organ TransplantHematopoietic Cell TransplantRespiratory Viral Infection
Arkansas Children's Hospital Research Institute2,000 enrolled27 locationsNCT05550298
Recruiting

Infectious Disease (ID) Testing OUtreach in Carceral Hubs

HIV Infections
Boston Medical Center75 enrolled1 locationNCT06679751
Recruiting
Phase 2

Tesamorelin as an Adjunct to Exercise for Improving Physical Function in HIV

FrailtyAgingHIV-1-infection+2 more
Massachusetts General Hospital100 enrolled2 locationsNCT06554717
Recruiting
Not Applicable

Texting to Reduce Human Immunodeficiency Virus (HIV) Risk

HIV Infections
Boston University266 enrolled2 locationsNCT06088277
Recruiting
Phase 1Phase 2

A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors

Advanced Solid TumorsCarcinomaNeoplasms+9 more
Marengo Therapeutics, Inc.365 enrolled32 locationsNCT05592626
Recruiting
Phase 2

Evaluating the Efficacy and Safety of Saline Irrigation as an Add-On Therapy for Retained Pleural Infections [LYTICS +]

Pleural EffusionsPleural Effusion DisorderPleural Effusion Associated With Pulmonary Infection
Beth Israel Deaconess Medical Center96 enrolled1 locationNCT06713382
Recruiting
Phase 3

SmartSteps: A Context-Aware, PrEP Adherence Intervention for Individuals With Substance Use Disorder

HIV InfectionsSubstance UseAdherence, Treatment+1 more
Brigham and Women's Hospital40 enrolled1 locationNCT05378399