Phase 3 Infection Clinical Trials
158 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 158 trials
Recruiting
Phase 3
A Phase 3 Study of Revaccination in Subsequent Pregnancies With Bivalent RSV Vaccine and Duration of Protection of a Single Dose
RSV Infection
Pfizer550 enrolled97 locationsNCT06866405
Recruiting
Phase 3
A Study to Learn About the Study Medicine Ibuzatrelvir in Adults With COVID-19 Who Are Severely Immunocompromised
COVID-19 Infection
Pfizer300 enrolled147 locationsNCT07013474
Recruiting
Phase 3
A Study to Learn About a Study Medicine Called Ibuzatrelvir in Adult and Adolescent Patients With COVID-19 Who Are Not Hospitalized But Are at Risk For Severe Disease
COVID-19 (SARS-CoV-2) infection
Pfizer2,330 enrolled246 locationsNCT06679140
Recruiting
Phase 3
PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation
InfectionsInjury LegAmputation+6 more
Major Extremity Trauma Research Consortium250 enrolled13 locationsNCT05699174
Recruiting
Phase 3
STI Testing to Enhance PrEP Use in Pregnancy
PregnancySexually Transmitted Infections (STIs)PrEP Adherence
Botswana Harvard AIDS Institute Partnership600 enrolled1 locationNCT06919614
Recruiting
Phase 3
Letermovir (Prevymis) for CMV in Kidney and Pancreas Transplant Recipients
Cytomegalovirus InfectionsKidney Transplant InfectionPancreas Transplant
University of Wisconsin, Madison90 enrolled1 locationNCT06407232
Recruiting
Phase 3
A Phase III Study to Evaluate the Efficacy and Safety of Libevitug in Participants With Chronic HDV Infection (D-clear Study)
Chronic Hepatitis D Infection
Huahui Health160 enrolled1 locationNCT07499544
Recruiting
Phase 3
A Trial to Treat Polyomavirus Infections (BKPyV) in Kidney and Simultaneous Kidney Pancreas Transplant Recipients
Kidney Transplant Failure and RejectionBK ViremiaKidney Transplant Infection
The University of Queensland280 enrolled13 locationsNCT05325008
Recruiting
Phase 2Phase 3
A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)
Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled56 locationsNCT07266831
Recruiting
Phase 3
Fecal Microbiota Transplantation in Clostridioides Difficile Infection First Episode and First Recurrence
Clostridioides Difficile Infection
Benoit Guery100 enrolled8 locationsNCT05266807
Recruiting
Phase 3
VE303 for Prevention of Recurrent Clostridioides Difficile Infection
Clostridium Difficile Infection RecurrenceClostridium DifficileClostridioides Difficile Infection+7 more
Vedanta Biosciences, Inc.852 enrolled215 locationsNCT06237452
Recruiting
Phase 3
A Study on the Immune Response and Safety of Vaccine Against Respiratory Syncytial Virus Given to Chinese Adults 18 to 59 Years of Age at Increased Risk of Respiratory Syncytial Virus Disease
Respiratory Syncytial Virus Infections
GlaxoSmithKline750 enrolled15 locationsNCT07220109
Recruiting
Phase 3
A Study to Evaluate the Effectiveness of Long-acting (LA) Cabotegravir (CAB) + Rilpivirine (RPV) LA When Given to Participants With Detectable HIV-1
HIV Infections
ViiV Healthcare332 enrolled89 locationsNCT06694805
Recruiting
Phase 3
Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT
Post Operative Surgical Site Infection
Major Extremity Trauma Research Consortium1,200 enrolled31 locationsNCT04678154
Recruiting
Phase 3
Infection Prophylaxis in Total Joint Replacement
Periprosthetic Joint Infection
Hamilton Health Sciences Corporation21,006 enrolled1 locationNCT06126614
Recruiting
Phase 3
A Phase 3 Efficacy and Safety Study of Fosmanogepix for the Treatment of Adult Patients With Invasive Mold Infections.
Invasive Mold Infections
Basilea Pharmaceutica234 enrolled52 locationsNCT06925321
Recruiting
Phase 3
Comparing The Safety And Efficacy Of DEFENCATH® In Reducing Central-Line Bloodstream Infections (CLABSIs) In Adults Receiving Total Parenteral Nutrition Through A Central Venous Catheter (CVC)
Central Line Associated Blood Stream Infections (CLABSI)
CorMedix200 enrolled22 locationsNCT06822426
Recruiting
Phase 3
Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study
COVID-19Lower Respiratory Tract InfectionImmunocompromised+1 more
Ansun Biopharma, Inc.274 enrolled67 locationsNCT03808922
Recruiting
Phase 3
A Clinical Trial on Safety in Pregnant Women and How Well the Infant is Protected Against RSV-associated Lower Respiratory Tract Infection When the Pregnant Woman Receives the Approved RSV Vaccine Compared to a Placebo.
preterm labourRSV ImmunisationRSV Infections
University of Witwatersrand, South Africa13,000 enrolled11 locationsNCT06955728
Recruiting
Phase 2Phase 3
Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty
Prosthetic joint infection
Peptilogics240 enrolled9 locationsNCT07214311