Phase 2 Infection Clinical Trials

224 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 224 trials

Recruiting
Phase 1Phase 2

Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission

HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 1Phase 2

A Phase I Study of Mozobil in the Treatment of Patients With WHIMS

NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting
Phase 2

Rhu-pGSN for Acute Respiratory Distress Syndrome (ARDS)

InfectionsAcute Respiratory Distress Syndrome
BioAegis Therapeutics Inc.600 enrolled70 locationsNCT05947955
Recruiting
Phase 2

Cytotoxic T Lymphocytes in Treating Patients With Malignancies With BK and/or JC Virus

Merkel Cell CarcinomaMalignant NeoplasmAcquired Immunodeficiency Syndrome+5 more
M.D. Anderson Cancer Center100 enrolled1 locationNCT02479698
Recruiting
Phase 2

A Study to Learn About the Study Medicine Aztreonam-Avibactam (ATM-AVI) in Infants and Newborns Admitted in Hospitals With Bacterial Infection (CHERISH)

Gram-negative Bacterial Infection
Pfizer48 enrolled26 locationsNCT06462235
Recruiting
Phase 2

Study of 2 Medicines (Aztreonam and Avibactam) Compared to Best Available Therapy for Serious Gram-negative Infections

Gram-Negative Bacterial Infections
Pfizer48 enrolled24 locationsNCT05639647
Recruiting
Phase 1Phase 2

Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1

HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Phase 2

A Study of S-337395 in Symptomatic Nonhospitalized Adults With Respiratory Syncytial Virus (RSV) Who Are at High Risk of Progression to Severe Disease

Respiratory Syncytial Virus Infections
Shionogi192 enrolled73 locationsNCT07214571
Recruiting
Phase 2

A Clinical Trial Evaluating the Safety and Efficacy of AP1189 Versus Placebo as an add-on to Standard of Care in Participants With Respiratory Insufficiency Expected to be Caused by Infection With Respiratory Viruses

Respiratory Viral Infection
SynAct Pharma Aps96 enrolled11 locationsNCT07633288
Recruiting
Phase 1Phase 2

Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV)

Systemic Inflammatory Response SyndromeSARS CoV-2Respiratory distress syndrome+2 more
PEACHES BIOTECH50 enrolled3 locationsNCT06684379
Recruiting
Phase 2

Phase 2 EL219 Versus Liposomal Amphotericin B or Voriconazole for Early Antifungal Therapy

Invasive Mould Infection
Elion Therapeutics, Inc.60 enrolled11 locationsNCT07215273
Recruiting
Phase 2

Nivolumab in Epstein-Barr Virus (EBV)-Positive Lymphoproliferative Disorders and EBV-Positive Non-HodgkinLymphomas

LymphomaEpstein-Barr Virus InfectionsLymphoproliferative Disorder+1 more
National Cancer Institute (NCI)40 enrolled1 locationNCT03258567
Recruiting
Phase 2Phase 3

A Clinical Study of Islatravir and Ulonivirine for People With HIV-1 Who Have Not Been Treated Before (MK-8591B-062)

Human Immunodeficiency Virus Type 1 (HIV-1) Infection
Merck Sharp & Dohme LLC570 enrolled56 locationsNCT07266831
Recruiting
Phase 2

Prevention of Recurrent C. Difficile Infection Study With AZD5148 Monoclonal Antibody

Clostridioides Difficile Infection
AstraZeneca230 enrolled114 locationsNCT07285213
Recruiting
Phase 2

Open Label Trial of Oral Letermovir for CMV Prophylaxis in Thoracic Transplant Recipients

Cytomegalovirus InfectionsTransplant-Related Disorder
University of Pennsylvania80 enrolled1 locationNCT06066957
Recruiting
Phase 1Phase 2

A Study of BLB-201 RSV Vaccine in Infants and Children

Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.137 enrolled15 locationsNCT05655182
Recruiting
Phase 2

Remdesivir for the Treatment of Upper Respiratory Tract Infection Due to RSV in Immunocompromised Individuals

Hematopoietic and Lymphatic System NeoplasmAutoimmune DiseaseRespiratory Syncytial Virus Infection
Fred Hutchinson Cancer Center60 enrolled3 locationsNCT06817889
Recruiting
Phase 2

Dolutegravir Versus Dolutegravir in Combination With Tenofovir for the Treatment of HTLV-1 Infection

HTLV-1 InfectionNeuritisHTLV I Associated Myelopathies+1 more
Carlos Brites146 enrolled1 locationNCT07555431
Recruiting
Phase 1Phase 2

The Tatelo Plus Study

HIV InfectionsHIV
National Institute of Allergy and Infectious Diseases (NIAID)41 enrolled2 locationsNCT06508749
Recruiting
Phase 2

Safety, Immunogenicity, and Efficacy of Therapeutic Mycobacterium Bovis BCG (BOOST)

Mycobacterium Infections, NontuberculousMycobacterium Avium-Intracellulare Infection
University of Virginia48 enrolled1 locationNCT07094711