Phase 4 Infection Clinical Trials
181 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 181 trials
Recruiting
Phase 4
Optimization of Beta-lactam Dosing in Critically Ill Patients With Cystatin C (OPTIMIZE-GNI)
Bacterial infection
National Institute of Allergy and Infectious Diseases (NIAID)200 enrolled10 locationsNCT06709521
Recruiting
Phase 4
A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments
HIV-1-infection
Gilead Sciences350 enrolled15 locationsNCT06337032
Recruiting
Phase 4
Trial of an AI-enabled Digital Stethoscope to Improve Antibiotic Stewardship
Respiratory Infections in Children
Johns Hopkins University2,500 enrolled1 locationNCT07362433
Recruiting
Phase 4
Itraconazole Therapy In Bronchiectasis With Airway Mold
BronchiectasisFungal Infection of Upper Respiratory Tract
Mayo Clinic30 enrolled1 locationNCT07283497
Recruiting
Phase 4
Letermovir Prophylaxis Duration Guided by CMV-Specific T-cell Monitoring After Allo-HSCT.
Graft vs Host DiseaseHematopoietic Stem Cell TransplantationCytomegalovirus Infections+1 more
WeiShi120 enrolled12 locationsNCT07569653
Recruiting
Phase 4
Daptomycin vs. Vancomycin for the Treatment of Methicillin Resistant S. Aureus Bacteremia
Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+2 more
Todd C. Lee MD MPH FIDSA300 enrolled16 locationsNCT06637332
Recruiting
Phase 4
Menopausal HT for Women Living With HIV (HoT)
MenopauseHIV Infection
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections105 enrolled23 locationsNCT06856174
Recruiting
Phase 4
Open-Label Study to Assess Safety and Time to Catheter-related Bloodstream Infections (CRBSI) in Subjects From Birth to < 18 Years of Age
Catheter-Related Infections
CorMedix36 enrolled6 locationsNCT06714864
Recruiting
Phase 4
Once Daily Intrapleural Enzyme Therapy in Complicated Parapneumonic Effusion or Empyema
EmpyemaPleural EffusionPleural Effusion Associated With Pulmonary Infection+5 more
University of North Carolina, Chapel Hill270 enrolled6 locationsNCT07095361
Recruiting
Phase 4
Doxycycline Prophylaxis for Prevention of Sexually Transmitted Infections
ChlamydiaSyphilisSexually Transmitted Infections (STIs)+1 more
Westat760 enrolled13 locationsNCT06738407
Recruiting
Phase 4
Betadine vs Sterile Water for Periurethral Preparation
Urinary Tract Infection BacterialCatherization
University of Louisville148 enrolled2 locationsNCT07044726
Recruiting
Phase 4
Got Doxy- 'Flipping the Script' on STI PEP
Sexually Transmitted Infections (STI)
Emory University200 enrolled2 locationsNCT07215325
Recruiting
Phase 4
Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).
Necrotizing Soft Tissue Infection
Ole Hyldegaard1,480 enrolled1 locationNCT07489274
Recruiting
Phase 4
Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia
Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)Staphylococcus Aureus BacteraemiaStaphylococcal Bacteraemia+1 more
Region Skane420 enrolled1 locationNCT06726395
Recruiting
Phase 4
Intraosseous vs. Intravenous Vancomycin Prophylaxis for Diabetic Foot Amputations: A Randomized Trial
Diabetic Foot DiseaseDiabetic Foot InfectionDiabetic Amputation Foot Wound
Başakşehir Çam & Sakura City Hospital40 enrolled1 locationNCT07338773
Recruiting
Phase 4
Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication
Peptic ulcer diseaseHelicobacter Pylori InfectionDyspepsia+2 more
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh80 enrolled2 locationsNCT07537634
Recruiting
Phase 4
Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)
SepsisInfectionsBacteremia
Murdoch Childrens Research Institute40 enrolled4 locationsNCT05770622
Recruiting
Phase 4
PeRiOperative Medicine Platform Trial
Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4
Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection
Helicobacter Pylori Infection
National Taiwan University Hospital450 enrolled1 locationNCT05332444
Recruiting
Phase 4
Comparison of Two Strategies for Administering the R21-Matrix M Vaccine in a Context of Seasonal Malaria Transmission in Chad
Malaria infectionMalaria Vaccines
Epicentre70,000 enrolled1 locationNCT07038837