Phase 4 Infection Clinical Trials

160 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 160 trials

Recruiting
Phase 4

Got Doxy- 'Flipping the Script' on STI PEP

Sexually Transmitted Infections (STI)
Emory University200 enrolled2 locationsNCT07215325
Recruiting
Phase 4

Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).

Necrotizing Soft Tissue Infection
Ole Hyldegaard1,480 enrolled1 locationNCT07489274
Recruiting
Phase 4

Comparison of Cloxacillin and Benzylpenicillin in Penicillin Susceptible S. Aureus Bacteraemia

Staphylococcus Aureus Bloodstream Infections (BSI; Bacteremia)Staphylococcus Aureus BacteraemiaStaphylococcal Bacteraemia+1 more
Region Skane420 enrolled1 locationNCT06726395
Recruiting
Phase 4

Intraosseous vs. Intravenous Vancomycin Prophylaxis for Diabetic Foot Amputations: A Randomized Trial

Diabetic Foot DiseaseDiabetic Foot InfectionDiabetic Amputation Foot Wound
Başakşehir Çam & Sakura City Hospital40 enrolled1 locationNCT07338773
Recruiting
Phase 4

Vonoprazan-based Versus Esomeprazole-based Triple Therapy for Helicobacter Pylori Eradication

Helicobacter Pylori InfectionDyspepsia
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh80 enrolled2 locationsNCT07537634
Recruiting
Phase 4

Improving Therapeutic Drug Monitoring and Dosing for Vancomycin in Young Infants With Infections (VANCAPP) (Part 2)

SepsisInfectionsBacteremia
Murdoch Childrens Research Institute40 enrolled4 locationsNCT05770622
Recruiting
Phase 4

PeRiOperative Medicine Platform Trial

Quality of LifeAnaesthesiaSurgical Site Infection After Major Surgery+2 more
Monash University7,800 enrolled2 locationsNCT07186634
Recruiting
Phase 4

Efficacies of Susceptibility-guided vs Empiric Therapy for Rescue Treatment of Helicobacter Pylori Infection

Helicobacter Pylori Infection
National Taiwan University Hospital450 enrolled1 locationNCT05332444
Recruiting
Phase 4

Topical Steroids to Prevent Recurrent Urinary Tract Infections in Uncircumcised Male Infants: a Pilot Study

Urinary Tract Infection
Baylor College of Medicine40 enrolled3 locationsNCT07508124
Recruiting
Phase 4

Immunogenicity and Safety PCV-20 of the Vaccine Administered During an Acute Febrile Illness in Adults

Pneumococcal InfectionsAcute Febrile Illness
Centre Hospitalier Universitaire de Saint Etienne1,052 enrolled24 locationsNCT06822907
Recruiting
Phase 4

Duration of Cardiac Antimicrobial Prophylaxis Outcomes Study

Surgical Site Infection
Monash University9,180 enrolled27 locationsNCT05447559
Recruiting
Phase 4

Single-arm, Prospective Study of the Efficacy and Safety of Paiteling®Antibacterial Liquid in the Treatment of Persistent Cervical HR-HPV Infection

Persistent HR-HPV Infection of the Cervix
The First Hospital of Jilin University115 enrolled1 locationNCT07493824
Recruiting
Phase 4

Antibiotics for Prevention of Infection Following Orthognathic Surgery

Orthognathic Surgical Site Infection
Abdul El-Rabbany400 enrolled1 locationNCT05852158
Recruiting
Phase 4

Dabigatran vs. Oral Anti-Xa Inhibitors in S. Aureus Bacteremia

Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+3 more
McGill University Health Centre/Research Institute of the McGill University Health Centre300 enrolled1 locationNCT06650501
Recruiting
Phase 4

Gelaspan vs Crystalloid Therapy in Sepsis

SepsisIntra-Abdominal Infections
Shanghai Zhongshan Hospital318 enrolled9 locationsNCT07172451
Recruiting
Phase 4

Clopidogrel vs. Aspirin for Cardiovascular Risk Reduction in Patients With S. Aureus Bacteremia

Staphylococcus Aureus EndocarditisStaphylococcus Aureus SepticemiaStaphylococcus Aureus Bloodstream Infection
Todd C. Lee MD MPH FIDSA300 enrolled1 locationNCT06650488
Recruiting
Phase 4

A Study to Provide Continued Access to Study Drug to Children and Adolescents Who Have Completed Clinical Studies Involving Gilead HIV Treatments

HIV-1-infection
Gilead Sciences350 enrolled14 locationsNCT06337032
Recruiting
Phase 4

Different Administration Regimens of CAZ-AVI in Combination With ATM for the Treatment of CR-GNB

Ceftazidime-avibactamAztreonamGram-negative Bacterial Infection+2 more
Jing Zhou144 enrolled1 locationNCT07478484
Recruiting
Phase 4

Preoperative Clindamycin Vaginal Cream Versus Vaginal Cleansing With Povidone-iodine on Postoperative Infections After Cesarean Section

Infection Control / MethodsSurgical Site Infection (SSI)
Beni-Suef University150 enrolled1 locationNCT07474194
Recruiting
Phase 4

Nasal Steroids, Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis

Acute SinusitisSinus Infection
Daniel Merenstein3,720 enrolled7 locationsNCT06076304