Phase 1 Infection Clinical Trials
169 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 169 trials
Recruiting
Phase 1Phase 2
Very Early Intensive Treatment of Infants Living With HIV to Achieve HIV Remission
HIV Infection
National Institute of Allergy and Infectious Diseases (NIAID)1,120 enrolled46 locationsNCT02140255
Recruiting
Phase 1Phase 2
A Phase I Study of Mozobil in the Treatment of Patients With WHIMS
NeutropeniaInfectionsWarts+2 more
National Institute of Allergy and Infectious Diseases (NIAID)20 enrolled1 locationNCT00967785
Recruiting
Phase 1
NADPH Oxidase Correction in mRNA-transfected Granulocyte-enriched Cells in Chronic Granulomatous Disease (CGD)
InfectionChronic Granulomatous Disease
National Institute of Allergy and Infectious Diseases (NIAID)25 enrolled1 locationNCT05189925
Recruiting
Phase 1
Safety and Pharmacokinetics of Ingavirin Forte, Capsules, 90 mg + 20 mg (Valenta Pharm JSC, Russia) Compared With Ingavirin, Capsules, 90 mg, Under Fasting and Fed Conditions.
InfluenzaAcute Respiratory Viral Infections
Valenta Pharm JSC36 enrolled1 locationNCT07645534
Recruiting
Phase 1
TETRAVI Multivirus CTL for Treatment of EBV, CMV, Adenovirus, and BK Infections Post Allogeneic SCT.
Viral Infection
Baylor College of Medicine47 enrolled2 locationsNCT04013802
Recruiting
Phase 1
R-MVST Cells for Treatment of Viral Infections
Epstein-Barr Virus InfectionsCytomegalovirus InfectionsBK Virus Infection+1 more
Columbia University36 enrolled1 locationNCT05183490
Recruiting
Phase 1Phase 2
Evaluation of Safety, Immunogenicity and Efficacy of a Triple Immune Regimen in Adults Initiated on ART During Acute HIV-1
HIV-1-infection
National Institute of Allergy and Infectious Diseases (NIAID)36 enrolled12 locationsNCT06071767
Recruiting
Phase 1Phase 2
Study on Safety and Efficacy of Two Doses of PRS CK STORM in the Modulation of the Cytokine Storm in Patients With Acute Respiratory Infection Caused by SARS-Cov-2, Influenza A, Influenza B and Respiratory Syncytial Virus (RSV)
Systemic Inflammatory Response SyndromeSARS CoV-2Respiratory distress syndrome+2 more
PEACHES BIOTECH50 enrolled3 locationsNCT06684379
Recruiting
Phase 1
Comparing Single Versus Repeat NMT on the Diversity of the Neonatal Nasal Microbiome
Staphylococcus AureusMicrobial ColonizationNeonatal Infection
Johns Hopkins University175 enrolled1 locationNCT06283355
Recruiting
Phase 1
Clinical Trial to Evaluate the Safety and Immunogenicity of Hiltonol, Poly-ICLC-adjuvanted CD40.HIVRI.Env (VRIPRO) in Adult Participants Who Previously Participated in HVTN 706
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)40 enrolled9 locationsNCT06665646
Recruiting
Phase 1
Controlled Human Infection Study of Orally Administered Trichuris Trichiura Eggs in Naïve Adults
WhipwormTrichuriasisControlled Human Infection
George Washington University18 enrolled2 locationsNCT05706116
Recruiting
Phase 1
Fecal Microbiota Transplantation in an Expanded Ulcerative Colitis Population
Inflammatory Bowel DiseasesUlcerative ColitisClostridioides Difficile Infection
University of Alberta85 enrolled2 locationsNCT07401680
Recruiting
Phase 1Phase 2
A Study of BLB-201 RSV Vaccine in Infants and Children
Respiratory Syncytial Virus Infections
Blue Lake Biotechnology Inc.137 enrolled15 locationsNCT05655182
Recruiting
Phase 1
Dasatinib for HIV-1 Reservoir Reduction
HIV Infections
National Institute of Allergy and Infectious Diseases (NIAID)14 enrolled3 locationsNCT07342491
Recruiting
Phase 1
A Phase I Clinical Study of AHB - 171 in Healthy Participants(HP) and Chronic Hepatitis B (CHB) Participants
Chronic Hepatitis B Infection
Ausper Biopharma Co., Ltd.110 enrolled1 locationNCT07511218
Recruiting
Phase 1Phase 2
The Tatelo Plus Study
HIV InfectionsHIV
National Institute of Allergy and Infectious Diseases (NIAID)41 enrolled2 locationsNCT06508749
Recruiting
Phase 1
Safety and Antiviral Activity of a Monoclonal Hepatitis B Antibody: a Phase 1b, Open-label Trial in Individuals With Chronic Hepatitis D Infection
Hepatitis D, ChronicHepatitis B Chronic Infection
Aarhus University Hospital15 enrolled2 locationsNCT07610772
Recruiting
Phase 1Phase 2
Clinical Trial of Recombinant RSV Vaccine (CHO Cell) (Adjuvanted) in Chinese Population Aged 18 Years and Older.
Respiratory Syncytial Virus Infections
Ab&B Bio-tech Co., Ltd.JS470 enrolled1 locationNCT07582796
Recruiting
Phase 1
MK-4646 Multiple Dose Trial in Participants With Human Immunodeficiency Virus Type 1 (HIV-1) (MK-4646-003)
HIV Infection
Merck Sharp & Dohme LLC28 enrolled2 locationsNCT07042945
Recruiting
Phase 1
A Safety Assessment of Oral Letermovir in Infants With Symptomatic Congenital Cytomegalovirus
Congenital Cytomegalovirus Infection
National Institute of Allergy and Infectious Diseases (NIAID)12 enrolled10 locationsNCT06118515