Phase 3 Intensive Care Clinical Trials
16 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–16 of 16 trials
Recruiting
Phase 3
Evaluation of the Analgesia by Serratus Plane Block During Pleural Drainage in Intensive Care Unit.
AnalgesiaIntensive Care UnitLidocaine
Centre Hospitalier Universitaire, Amiens70 enrolled1 locationNCT03984656
Recruiting
Phase 3
RECOMMEND Platform Trial
Intensive Care MedicineCritical IllnessCardiac Arrest (CA)+2 more
Australian and New Zealand Intensive Care Research Centre600 enrolled3 locationsNCT06526533
Recruiting
Phase 3
Canadian Critical Care Comparative Effectiveness Platform
NutritionVasopressorIntensive Care Unit ICU+1 more
Université de Sherbrooke5,500 enrolled8 locationsNCT06605144
Recruiting
Phase 3
PRophylaxis Against Early VENTilator-associated Infections in Acute Brain Injury
Intensive Care MedicineAcute brain injuryQuality of Life+4 more
The George Institute3,300 enrolled9 locationsNCT06819592
Recruiting
Phase 3
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
Intensive Care Units, PediatricAnesthetics, InhalationMechanically Ventilated, Critically Ill Children
Sunnybrook Health Sciences Centre60 enrolled3 locationsNCT05867472
Recruiting
Phase 2Phase 3
Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo
Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 3
Dexmedetomidinine in the Prevention of Postoperative Delirium in the Intensive Care Unit After Cardiac Surgery
Intensive Care Unit Delirium
University of Novi Sad200 enrolled1 locationNCT05849597
Recruiting
Phase 2Phase 3
Muscle growth and anabolism in intensive care survivors
Intensive CareCritical illness nutrition
Sir Charles Gairdner Hospital60 enrolled3 locationsACTRN12623000729628
Completed
Phase 3
Early versus delayed aperient use in the intensive care unit
Bowel management in intensive care
Austin Health880 enrolled1 locationACTRN12623000112662
Recruiting
Phase 3
The SuDDICU Study of Antibiotic Prophylaxis in Critical Illness
Known or suspected infection in critically ill patients in the Intensive Care Unit (ICU)
The George Institute for Global Health15,000 enrolled18 locationsACTRN12615000411549
Completed
Phase 2Phase 3
Permissive HyperthErmiA Through Avoidance of Paracetamol in Known or Suspected Infection in the Intensive Care Unit (ICU)
Known or suspected infection in critically ill patients in the Intensive Care Unit (ICU)
Medical Research Institute of New Zealand700 enrolled1 locationACTRN12612000513819
Not Yet Recruiting
Phase 2Phase 3
The effect of saline instillation during physiotherapy (SIP) in the intensive care unit - a randomized crossover trial
Critically ill intubated intensive care patients
University of Queensland35 enrolled1 locationACTRN12612000432819
Not Yet Recruiting
Phase 2Phase 3
Sedation Practice in Intensive Care in Australia and New Zealand- A Pilot Study
Sedation in intensive care patients
ANZIC-research centre, Monash University60 enrolled1 locationACTRN12611000166976
Completed
Phase 3Phase 4
Crystalloid versus Hydroxy-Ethyl Starch Trial - A multi-centre randomized controlled trial of fluid resuscitation with starch (6% hydroxyl starch 130/0/4) compared to saline (0.9%) sodium chloride in intensive care patients on mortality.
Fluid resuscitation in intensive care patients
The George Institute for Global Health7,000 enrolled2 locationsACTRN12609000245291
Terminated
Phase 3
Dexmedetomidine and Haloperidol for the management of emergence delirium in intensive care
Delirium in mechanically ventilated intensive care patients
Prince of Wales Hospital60 enrolled1 locationACTRN12606000085572
Active
Phase 3
Randomised controlled trial of maintenance fluids in paediatric intensive care.
Children admitted to paediatric intensive care (PICU)
Women's and Children's Hospital Adelaide. Not sponsored financially.48 enrolled1 locationACTRN12605000061639