ISS Clinical Trials in Boston, Massachusetts

26 recruitingBoston, Massachusetts

Showing 120 of 26 trials

Recruiting
Phase 3

Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled248 locationsNCT06422806
Recruiting
Not Applicable

IMPRoving Outcomes in Vascular DisEase - Aortic Dissection

Type B Aortic Dissection
Duke University1,100 enrolled63 locationsNCT06087029
Recruiting
Phase 3

Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)

Soft Tissue Sarcoma
Polaris Group300 enrolled31 locationsNCT05712694
Recruiting
Not Applicable

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

Aortic Dissection
W.L.Gore & Associates112 enrolled16 locationsNCT06827990
Recruiting

Multi-center Evaluation of the Clinical Utility of ESD in the Western Population

Endoscopic Submucosal Dissection
University of Florida300 enrolled3 locationsNCT02989818
Recruiting
Phase 2

A Study Evaluating the Safety and Efficacy of Inhaled AP01 in Participants With Progressive Pulmonary Fibrosis

Progressive Pulmonary FibrosisInterstitial Lung DiseasePulmonary Fibrosis+4 more
Avalyn Pharma Inc.375 enrolled152 locationsNCT06329401
Recruiting
Phase 3

Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial

RISS Stage I Plasma Cell MyelomaRISS Stage II Plasma Cell MyelomaPlasma Cell Myeloma
ECOG-ACRIN Cancer Research Group1,450 enrolled600 locationsNCT04566328
Recruiting
Not Applicable

Improving Adolescent and Young Adult Self-Reported Data in ECOG-ACRIN Trials

MelanomaBreast Cancer, NOSCNS Primary Tumor, NOS+9 more
Eastern Cooperative Oncology Group400 enrolled347 locationsNCT05108298
Recruiting
Phase 1

Ziftomenib Maintenance Post Allo-HCT

Acute Myeloid LeukemiaAcute Myeloid Leukemia in RemissionKMT2A Rearrangement+1 more
Massachusetts General Hospital22 enrolled2 locationsNCT06440135
Recruiting
Phase 1

Venetoclax Basket Trial for High Risk Hematologic Malignancies

Acute Lymphoblastic Leukemia, in RelapseAcute Leukemia of Ambiguous LineageAcute Lymphoblastic Leukemia With Failed Remission+8 more
Andrew E. Place, MD30 enrolled5 locationsNCT05292664
Recruiting
Phase 1

Phase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid Tumors

Advanced Solid TumorMetastatic Solid TumorSolid Tumor+4 more
Ankyra Therapeutics, Inc97 enrolled5 locationsNCT06171750
Recruiting
Not Applicable

Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT

Lack of Keratinized GingivaMucogingival Deformity - Insufficient Keratinized Tissue
Harvard Medical School (HMS and HSDM)12 enrolled1 locationNCT07440303
Recruiting
Not Applicable

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

Aortic AneurysmAortic DiseasesAortic Aneurysm and Dissection+3 more
Vascutek Ltd.150 enrolled23 locationsNCT07078383
Recruiting
Not Applicable

Liquid Biopsy in Ewing Sarcoma and Osteosarcoma as a Prognostic And Response Diagnostic: LEOPARD

Ewing SarcomaPeripheral Primitive Neuroectodermal TumorEwing Sarcoma of Bone+3 more
Dana-Farber Cancer Institute340 enrolled15 locationsNCT06068075
Recruiting

The Physiology of Human Brown Adipose Tissue

ObesityAdipose Tissue, BrownAdipose Tissue
Beth Israel Deaconess Medical Center40 enrolled1 locationNCT04352244
Recruiting

The Myelin Disorders Biorepository Project

AdrenoleukodystrophyCockayne SyndromeRefsum Disease+63 more
Children's Hospital of Philadelphia12,000 enrolled23 locationsNCT03047369
Recruiting

Clinical Validation of Samsung Smartwatch

Mental Health IssueMajor Depressive DisorderMood Disorders
Massachusetts General Hospital220 enrolled1 locationNCT05767593
Recruiting

Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment

OsteosarcomaRecurrent LymphomaLymphoblastic Lymphoma+4 more
Children's Oncology Group420 enrolled79 locationsNCT01790152
Recruiting
Phase 1

Prevention of GvHD in Participants With Hematological Malignancies Undergoing Hematopoietic Stem Cell Transplant (HSCT)

Hematologic MalignancyGvHDGVHD,Acute+8 more
Tr1X, Inc.36 enrolled5 locationsNCT06462365
Recruiting

International Spontaneous Coronary Artery Dissection (SCAD) "iSCAD" Registry

Spontaneous Coronary Artery Dissection
SCAD Alliance1,000 enrolled31 locationsNCT04496687