Early Phase 1 ISS Clinical Trials
12 recruitingEarly Phase 1
What is a Early Phase 1 trial?
Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.
Showing 1–12 of 12 trials
Recruiting
Early Phase 1
Application of Contrast-enhanced Ultrasound in Monitoring Soft Tissue Sarcoma Response to Neoadjuvant Radiotherapy
Soft Tissue Sarcoma
Thomas Jefferson University10 enrolled1 locationNCT07436364
Recruiting
Early Phase 1
Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases
Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1
iMagemHTT-009- FIH Evaluation of Novel Mutant Huntingtin PET Radioligand [11C]CHDI-00491009
Huntington DiseasePositron Emission TomographyImaging+5 more
CHDI Foundation, Inc.27 enrolled1 locationNCT06634628
Recruiting
Early Phase 1
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Breast CancerBladder CarcinomaEsophageal Carcinoma+11 more
Var2 Pharmaceuticals32 enrolled1 locationNCT06645808
Recruiting
Early Phase 1
Study of Liraglutide (A Weight Loss Drug) in High Risk Obese Participants With Cognitive and Memory Issues
ObesityMultiple SclerosisLong COVID+4 more
University of Chicago30 enrolled1 locationNCT06171152
Recruiting
Early Phase 1
A Phase 0 Multicenter Study of the Pharmacodynamic Effects of Intratumoral Microdose Administration of PBA-0111 in Patients With Solid Tumors
Head and Neck Squamous Cell CarcinomaSoft Tissue Sarcoma Adult
Pure Biologics S.A.12 enrolled1 locationNCT06700070
Recruiting
Early Phase 1
NeuroFLiPP: Parametric PET of Neuroinflammation in Fatty Liver Disease
Positron Emission Tomography
University of California, Davis12 enrolled1 locationNCT06453915
Recruiting
Early Phase 1
[68Ga]Ga-Sa-DABI-4 PET Imaging of Stimulator of Interferon Gene Expression in Cancer Patients
CancerPositron Emission TomographyStimulator of Interferon Gene
First Affiliated Hospital of Chongqing Medical University30 enrolled1 locationNCT06419361
Recruiting
Early Phase 1
Phase I Study to Evaluate KP405 in Healthy and Parkinson's Disease Patients
Safety IssuesTolerance
Kariya Pharmaceuticals88 enrolled1 locationNCT06189170
Recruiting
Early Phase 1
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Advanced Bone and Soft Tissue Tumors
Soft Tissue SarcomaSarcomaOsteosarcoma+1 more
Shanghai Yunying Medical Technology9 enrolled1 locationNCT06171282
Recruiting
Early Phase 1
A Clinical Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors
SarcomaOsteosarcomaSarcoma,Soft Tissue+1 more
Shanghai Yunying Medical Technology20 enrolled1 locationNCT05851456
Recruiting
Early Phase 1
A Study of Murine CD19 CAR-T Therapy for Patients With Relapsed or Refractory CD19+ B-cell Hematological Malignancies
Acute Lymphoblastic LeukemiaNon-Hodgkin Lymphoma of Soft Tissue
Zhejiang University120 enrolled1 locationNCT04532281