Phase 3 ISS Clinical Trials
35 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 35 trials
Recruiting
Phase 3
Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas
Metastatic Dedifferentiated LiposarcomaStage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8+3 more
National Cancer Institute (NCI)365 enrolled248 locationsNCT06422806
Recruiting
Phase 3
Comparison of Weekly Somatrogon to Daily Genotropin in Children Born Small for Gestational Age or With Idiopathic Short Stature.
ISSSGA
Rabin Medical Center254 enrolled32 locationsNCT07226089
Recruiting
Phase 3
Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects With Leiomyosarcoma (ARGSARC)
Soft Tissue Sarcoma
Polaris Group300 enrolled31 locationsNCT05712694
Recruiting
Phase 3
Interest of Peri Operative CHemotherapy In Patients With CINSARC High-risk Localized Soft Tissue Sarcoma
Soft Tissue Sarcoma
Institut Claudius Regaud600 enrolled19 locationsNCT04307277
Recruiting
Phase 3
A Prospective Pivotal Study to Evaluate the Efficacy and Safety of Avastin® Bevacizumab (BEV) With or Without Microbubble-mediated Focused Ultrasound (FUS-MB) Using NaviFUS System in Recurrent Glioblastoma Multiforme Patients
NeoplasmsBrain TumorGlioblastoma+5 more
NaviFUS Corporation32 enrolled2 locationsNCT06496971
Recruiting
Phase 3
Testing the Use of Combination Therapy in Adult Patients With Newly Diagnosed Multiple Myeloma, the EQUATE Trial
RISS Stage I Plasma Cell MyelomaRISS Stage II Plasma Cell MyelomaPlasma Cell Myeloma
ECOG-ACRIN Cancer Research Group1,450 enrolled600 locationsNCT04566328
Recruiting
Phase 2Phase 3
Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo
Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 3
Affirmative Family and Individual Psychotherapy for Sexual and Gender Minority Adults and Their Nonaccepting Parents
Mental Health IssueParent-Child Relations
Yale University124 enrolled2 locationsNCT05766592
Recruiting
Phase 3
A Study to Learn About the Safety and Efficacy of the Drug Oleogel-S10 in Japanese Patients With Epidermolysis Bullosa
Skin DiseasesEpidermolysis BullosaConnective Tissue Disease+7 more
Chiesi Farmaceutici S.p.A.6 enrolled6 locationsNCT06917690
Recruiting
Phase 3
A Study to Investigate the Long-term Safety and Efficacy of Belimumab in Adults With Interstitial Lung Disease (ILD) Associated With Systemic Sclerosis (SSc) and Other Connective Tissue Diseases (CTD) (BLISSconneCTD-OLE)
Connective Tissue Diseases
GlaxoSmithKline514 enrolled10 locationsNCT06716606
Recruiting
Phase 2Phase 3
DETERMINE Trial Treatment Arm 06: Capmatinib in Adult Patients With Cancers Harbouring MET Dysregulations
MalignancyGastric CancerSoft Tissue Sarcoma+8 more
Cancer Research UK30 enrolled17 locationsNCT06988475
Recruiting
Phase 3
Study on Ketorolac for Improving Outcomes and Prognosis in Patients With Stanford Type A Aortic Dissection
InflammationAortic Dissection
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School360 enrolled1 locationNCT06968806
Recruiting
Phase 3
Benefit of Intensified Peri-operative Chemotherapy Within High-risk CINSARC Patients With Resectable Soft-tissue Sarcomas
Non-metastatic Soft-tissue SarcomaResectable
Institut Bergonié351 enrolled10 locationsNCT03805022
Recruiting
Phase 3
PSMA PET Combined With MRI for the Detection of PCa
Prostate CancerProstatic NeoplasmPCA+6 more
Telix Pharmaceuticals (Innovations) Pty Limited204 enrolled1 locationNCT07052214
Recruiting
Phase 2Phase 3
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia
Overweight and ObesityAtypical Endometrial HyperplasiaFertility Issues
Xiaojun Chen172 enrolled1 locationNCT05316493
Recruiting
Phase 2Phase 3
Weight Management Plus Megestrol Acetate in Early-stage Endometrioid Carcinoma
Endometrial CarcinomaOverweightObese+1 more
Xiaojun Chen89 enrolled1 locationNCT05316467
Recruiting
Phase 2Phase 3
Pancreatic Cancer Diagnosis With FAPI-PET Imaging
Pancreatic CancerFAPIPositron Emission Tomography+5 more
Turku University Hospital100 enrolled1 locationNCT07098598
Recruiting
Phase 2Phase 3
An Open Prospective Randomized Clinical Study of the Effectiveness, Tolerability and Safety of a Single Intraperitoneal Use of the Drug "Prospidelong, Powder for the Preparation of a Gel for Topical Use, 1000 mg in Vials, Package No. 1" in Patients With Disseminated Gastric Cancer, Phase I-II
Gastric Cancer With Peritoneal Dissemination
Research Institute for Physical Chemical Problems of the Belarusian State University120 enrolled1 locationNCT06232434
Recruiting
Phase 3
tislelizUMaB in canceR Patients With molEcuLar residuaL Disease
Soft Tissue SarcomaLung CancerCancer+2 more
Gustave Roussy, Cancer Campus, Grand Paris717 enrolled1 locationNCT06332274
Recruiting
Phase 3
tTF-NGR Randomized Study - STS
Soft Tissue Sarcoma
Universität Münster126 enrolled9 locationsNCT05597917