Phase 2 ISS Clinical Trials
127 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 127 trials
Recruiting
Phase 2
Assessment of the Long-term Efficacy of Moderately Hypofractionated Neoadjuvant Radiotherapy Soft Tissue Sarcoma in the Limbs or Trunk Wall
Soft Tissue Sarcoma AdultSoft Tissue Sarcoma (Excluding GIST)Soft Tissue Sarcoma of the Trunk and Extremities+1 more
Centre Oscar Lambret135 enrolled1 locationNCT07507773
Recruiting
Phase 2
Testing Atezolizumab With Selinexor in People ≥ 12 Years Old With Alveolar Soft Part Sarcoma, AXIOM Trial
Metastatic Alveolar Soft Part SarcomaAdvanced Soft Tissue SarcomaAdvanced Alveolar Soft Part Sarcoma+2 more
National Cancer Institute (NCI)27 enrolled13 locationsNCT05333458
Recruiting
Phase 2
Metformin Hydrochloride in Combination With Standard of Care Systemic Therapy in Previously Untreated Advanced Unresectable or Metastatic Soft Tissue Sarcoma
Sarcoma,Soft TissueSarcoma Metastatic
Wake Forest University Health Sciences50 enrolled2 locationsNCT07291297
Recruiting
Phase 1Phase 2
Trial of Single Protein Encapsulated Doxorubicin, SPEDOX-6 in Advanced Malignancies
Triple-Negative Breast CancerOvarian CancerCervical Cancer+3 more
University of California, Irvine67 enrolled1 locationNCT07064018
Recruiting
Phase 1Phase 2
Atezolizumab Plus Tivozanib in Immunologically Cold Tumor Types
Breast CancerOvarian CancerProstate Cancer+6 more
University of Florida29 enrolled1 locationNCT05000294
Recruiting
Phase 2Phase 3
Effect of Interferon Gamma as a Treatment for Post-aggressive Immunosuppression in Intensive Care Units, a Randomized Bayesian Double-blind Controlled Trial Versus Placebo
Post-aggressive ImmunosuppressionAdult Patients Admitted to Intensive Care With Initial Severity (SOFA of the First 24 Hours Post-admission ≥ 6Adult Under Mechanical Ventilation, and Presenting an mHLA-DR Less Than 8,000AB/C
Assistance Publique - Hôpitaux de Paris170 enrolled2 locationsNCT06694740
Recruiting
Phase 2
Combined Gastrointestinal Decontamination in Acute Severe Poisoning
Severe Poisoning With Cardiotropic or Psychotropic DrugAdmission to Intensive Care
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT07201311
Recruiting
Phase 2
Pegylated Liposomal Doxorubicin (PLD) Versus Active Surveillance for Advanced Soft Tissue Sarcoma Patients Who Had Controlled Disease After Standard Anthracycline-based Treatment (MELODY)
Advanced Soft Tissue Sarcoma
National Health Research Institutes, Taiwan81 enrolled7 locationsNCT06981637
Recruiting
Phase 1Phase 2
PSMA-specific CAR-T Cell Therapy
PSMA Positive Tumors or Tumor Tissues
Shenzhen Geno-Immune Medical Institute100 enrolled1 locationNCT04429451
Recruiting
Phase 1Phase 2
211At-BC8-B10 Followed by Donor Stem Cell Transplant in Treating Patients With Relapsed or Refractory High-Risk Acute Leukemia or Myelodysplastic Syndrome
Hematopoietic and Lymphoid Cell NeoplasmAcute Myeloid Leukemia in RemissionChronic Myelomonocytic Leukemia+9 more
Fred Hutchinson Cancer Center30 enrolled1 locationNCT03670966
Recruiting
Phase 2
XL092 (Zanzalintinib) for the Treatment of Patients With Metastatic or Unresectable Leiomyosarcoma, Bone Sarcoma or Translocation-associated Soft Tissue Sarcoma
Ewing SarcomaBone SarcomaSynovial Sarcomas+7 more
Northwestern University73 enrolled1 locationNCT06571734
Recruiting
Phase 1Phase 2
Testing the Addition of an Anti-cancer Drug, Abemaciclib, to the Usual Chemotherapy Treatment (Gemcitabine) for Soft Tissue Sarcoma
Metastatic Soft Tissue SarcomaMetastatic LeiomyosarcomaAdvanced Soft Tissue Sarcoma+5 more
National Cancer Institute (NCI)74 enrolled1 locationNCT06498648
Recruiting
Phase 2
Toripalimab Combined With CAV/IE Regimen
Soft Tissue Sarcoma
Sun Yat-sen University134 enrolled1 locationNCT04589741
Recruiting
Phase 2
Faecal Microbiota Transplantation After Allogeneic Stem Cell Transplantation
Chronic Lymphocytic LeukemiaHodgkin LymphomaMyeloma+4 more
University Hospital, Clermont-Ferrand150 enrolled20 locationsNCT04935684
Recruiting
Phase 2
5-Day Preoperative Radiation for Soft Tissue Sarcoma
Soft Tissue Sarcoma
Stanford University75 enrolled1 locationNCT06087861
Recruiting
Phase 1Phase 2
Scar Remodeling After Burn Injury Using Allogeneic Adipose-derived Stromal Cells
Scar Conditions and Fibrosis of SkinScar Quality Assessment and SafetyScar Tissue
Rigshospitalet, Denmark39 enrolled1 locationNCT07635875
Recruiting
Phase 2
Preoperative IMRT With Anlotinib and Penpulimab for Localized Sarcoma （SPARE-01）
Sarcoma,Soft TissueAnlotinibIntensity Modulated Radiotherapy+3 more
Cancer Institute and Hospital, Chinese Academy of Medical Sciences30 enrolled1 locationNCT05167994
Recruiting
Phase 2Phase 3
Weight Management Plus LNG-IUS/Megestrol Acetate in Endometrial Atypical Hyperplasia
Overweight and ObesityAtypical Endometrial HyperplasiaFertility Issues
Xiaojun Chen172 enrolled1 locationNCT05316493
Recruiting
Phase 2
A Study to Evaluate Pre-operative HYPOfractionated Radiation Therapy in Aged (≥ 70 Years Old) or "Fragile" (≥ 65 Years) Patients With Limb or Trunk Soft Tissue SARComa.
Soft Tissue Sarcoma
Institut Claudius Regaud48 enrolled11 locationsNCT06022159
Recruiting
Phase 1Phase 2
The Combination of Radiotherapy, Chemotherapy and Immunotherapy in High-Risk Localized Soft Tissue Sarcoma
High-Risk Localized Soft Tissue Sarcoma
Fudan University52 enrolled1 locationNCT05774275