Phase 4 ISS Clinical Trials
30 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 30 trials
Recruiting
Phase 4
Reversible Effects of Oral Contraceptive Removal on Serotonergic Neurotransmission
Healthy Adult FemalesThe Focus of the Study is to Investigate Reversible Effects of Combined Oral Contraceptive Use on Serotonergic Neurotransmission
Rigshospitalet, Denmark60 enrolled1 locationNCT07511439
Recruiting
Phase 4
Epicardial Adipose Tissue Composition and Heart Failure With Preserved Ejection Fraction
Heart Failure Preserved Ejection FractionEpicardial Adipose Tissue
University of Virginia192 enrolled1 locationNCT07178145
Recruiting
Phase 4
Adjunctive Hyperbaric Oxygen Treatment for Patients With Necrotizing Soft-Tissue Infection (HOT-NSTI Trial).
Necrotizing Soft Tissue Infection
Ole Hyldegaard1,480 enrolled1 locationNCT07489274
Recruiting
Phase 4
BoTox Into the Sternocleidomastoid Muscles (SCM)
Neck Muscle Issue
Boston Medical Center30 enrolled1 locationNCT06903975
Recruiting
Phase 4
Combined OFM and Vacuum-assisted Therapy for Expedited Regeneration Over Structures
Soft Tissue DefectsSoft Tissue WoundsTraumatic Soft Tissue Defect
Aroa Biosurgery Limited30 enrolled2 locationsNCT07385313
Recruiting
Phase 4
Restoring Facial Volume After GLP-1 Weight Loss With Radiesse
Volume Loss (Soft Tissue Ptosis or Atrophy )
Kalpna Kay Durairaj, MD, FACS48 enrolled1 locationNCT07419854
Recruiting
Phase 4
Pasteurised Donor Human Milk Supplementation for Term Babies
neonatal intensive care unitMental Health IssueHospital Length of Stay+4 more
The University of Queensland1,444 enrolled4 locationsNCT06993103
Recruiting
Phase 4
Application of Topical Oxygen Therapy Around Customized Healing Collar
Soft TissueHealing Abutment Influence on Gingival VolumeSoft Tissue Healing+1 more
Cairo University6 enrolled1 locationNCT07384403
Recruiting
Phase 4
Real World Safety & Efficacy Experience of Empagliflozin With or Without Metformin in T2DM Patients - EASE Study
Type II Diabetes MellitusEfficacy, SelfSafety Issues
Getz Pharma2,000 enrolled6 locationsNCT05164263
Recruiting
Phase 4
Androgen Effects on the Reproductive Neuroendocrine Axis, 2025 Version
Reproductive IssuesTransgenderism
University of California, San Diego80 enrolled1 locationNCT07092527
Recruiting
Phase 4
Luteal Phase Support in IUI MOH Treatment Luteal Phase Support in IUI MOH Treatment
Pregnancy RelatedFertility IssuesInfertility Unexplained+1 more
UMC Utrecht1,008 enrolled1 locationNCT05080569
Recruiting
Phase 4
MenB-FHbp or MenACWY-TT/MenB-FHbp Vaccine in MenB-4C Primed Young Adults
Neisseria Meningitidis
Emory University125 enrolled2 locationsNCT07197762
Recruiting
Phase 4
A Study to Test Tetrandrine Tablets for Connective Tissue Disease-Related Lung Disease
Interstitial Lung Disease (ILD)Connective Tissue Disease-associated Interstitial Lung Disease
Peking University Third Hospital100 enrolled1 locationNCT07319598
Recruiting
Phase 4
Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel
Gingival bleedingProsthesis Failure, DentalTissue Injury
Dow University of Health Sciences66 enrolled1 locationNCT07255976
Recruiting
Phase 4
Letrozole Plus Misoprostol Versus Misoprostol Alone for Treating Women With Missed Miscarriage
Miscarriage in First TrimesterMissed Miscarriage
Nishtar Medical University92 enrolled1 locationNCT07160855
Recruiting
Phase 4
Low-Dose Ketamine Infusion During Burn Wound Care
PainOpioidDissociation+1 more
University of Tennessee140 enrolled1 locationNCT06506565
Recruiting
Phase 4
Treatment Effects of Two Pharmaceutical Skin Care Creams for Xerotic Feet Among Persons with Diabetes
Diabetes MellitusSkin and Connective Tissue Diseases
Malmö University98 enrolled1 locationNCT06427889
Recruiting
Phase 4
Behavioral Comparison of Three Different Graft Materials to Increase Soft Tissue Thickness Around Dental Implants.
Soft Tissue AtrophyMucogingival Deformity on Edentulous RidgeEdentulous Alveolar Ridge
Universitat Internacional de Catalunya60 enrolled1 locationNCT04766255
Recruiting
Phase 4
Efficacy and Safety of Prophylactic Treatment for Pneumocystis Jirovecii Pneumonia in Patients With Autoimmune Inflammatory Rheumatic Disease
PreventionAutoimmune DiseasesConnective Tissue Disease+2 more
Tongji Hospital800 enrolled1 locationNCT06499233
Recruiting
Phase 4
Anlotinib Combined With Doxorubicin and Radiotherapy as Neoadjuvant Treatment for Soft Tissue Sarcoma
Soft Tissue SarcomaRadiotherapyDoxorubicin
Guangdong Provincial People's Hospital39 enrolled2 locationsNCT06506838