Kidney Transplant Rejection Clinical Trials

13 recruitingLast updated: May 5, 2026

Kidney Transplant Rejection Trials at a Glance

13 actively recruiting trials for kidney transplant rejection are listed on ClinicalTrialsFinder across 6 cities in 19 countries. The largest study group is Not Applicable with 2 trials, with the heaviest enrollment activity in Murray, Tampa, and Cleveland. Lead sponsors running kidney transplant rejection studies include Erasmus Medical Center, Insight Molecular Diagnostics, and AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC.

Browse kidney transplant rejection trials by phase

Treatments under study

About Kidney Transplant Rejection Clinical Trials

Looking for clinical trials for Kidney Transplant Rejection? There are currently 13 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Kidney Transplant Rejection trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Kidney Transplant Rejection clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 113 of 13 trials

Recruiting
Phase 2Phase 3

A Study to Investigate the Efficacy and Safety of Frexalimab Versus Tacrolimus in Adults Undergoing Kidney Transplantation

Kidney Transplant Rejection
Sanofi526 enrolled10 locationsNCT07412470
Recruiting

Trifecta-Kidney cfDNA-MMDx Study

Kidney Transplant Rejection
University of Alberta300 enrolled31 locationsNCT04239703
Recruiting

Evaluating Urinary CXCL10 for Enhanced Detection of Acute Rejection in Kidney Transplant Patients With Low DD-CFDNA

Kidney Transplant Rejection
Virginia Commonwealth University50 enrolled1 locationNCT07415876
Recruiting
Not Applicable

Treatment of Chronic Active Antibody Mediated Rejection With Tocilizumab

Kidney Transplant Rejection
Shahid Beheshti University of Medical Sciences50 enrolled1 locationNCT07006532
Recruiting

Platelet Aggregation in the Diagnosis of Acute Graft Rejection

Kidney Transplant RejectionPlatelet Aggregation
University Hospital, Martin60 enrolled1 locationNCT07275541
Recruiting

Validation of Donor-Derived Cell-Free DNA (Dd-cfDNA) for Kidney Transplant Monitoring

Kidney Transplant Rejection
Insight Molecular Diagnostics125 enrolled10 locationsNCT07060716
Recruiting

Australian Genomics Of Chronic Allograft Dysfunction Study

Kidney Transplant; ComplicationsKidney Transplant Rejection
Western Sydney Local Health District500 enrolled2 locationsNCT06314230
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Kidney Transplant to Reduce Rejection Risk

Kidney FailureEnd Stage Renal DiseaseKidney Tumor+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053462
Recruiting

Impact of the Microbiota on the Likelihood of Renal Graft Rejection

Kidney Transplant Rejection
Institut National de la Santé Et de la Recherche Médicale, France70 enrolled9 locationsNCT04736381
Recruiting
Not Applicable

Added Value of 18 FDG Pet-scanner in Diagnosis and Management of Subclinical Rejection in Kidney Transplant Patients

Kidney Transplant; ComplicationsKidney Transplant Rejection
University of Liege50 enrolled1 locationNCT04702022
Recruiting

Expanding the Scope of Post-transplant HLA-specific Antibody Detection and Monitoring in Renal Transplant Recipients

DiagnosisKidney Transplant; ComplicationsKidney Transplant+4 more
Liverpool University Hospitals NHS Foundation Trust282 enrolled1 locationNCT06025240
Recruiting

Reduced-dose Alemtuzumab for Kidney Transplant Rejection

Kidney Transplant Rejection
Erasmus Medical Center25 enrolled1 locationNCT06100965
Recruiting

Multi Center Observation of Sentinel Skin Graft for Detecting Acute Rejection After Renal Transplantation

Kidney Transplant Rejection
Second Affiliated Hospital, School of Medicine, Zhejiang University24 enrolled3 locationsNCT05600634