Phase 2 Knee Clinical Trials

66 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 66 trials

Recruiting
Phase 2

Enhancing Modulation Effects of Baduanjin Through Neuromodulation for Knee OA

Knee Osteoarthritis
Massachusetts General Hospital140 enrolled1 locationNCT05839535
Recruiting
Phase 1Phase 2

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

Total Knee AnthroplastyOsteoarthritis PrimaryBilateral Knee Osteoarthritis+1 more
Unity Health Toronto60 enrolled1 locationNCT06809998
Recruiting
Phase 2

CBP-0276 to Reduce Opioid Use in Adults Undergoing Major Orthopedic Surgery

Hip or Knee Replacement
Clarent Biopharma, Inc.80 enrolled1 locationNCT07687966
Recruiting
Phase 1Phase 2

Total Intravenous Anesthesia vs Spinal Anesthesia in Patients Undergoing Unilateral Primary Total Knee Arthroplasty

Total Knee Arthroplasty (TKA)
University of Chicago150 enrolled1 locationNCT07672301
Recruiting
Phase 2

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

diabetic neuropathic painChronic Low-back PainOsteoarthritis, Knee
Eli Lilly and Company10,000 enrolled64 locationsNCT05986292
Recruiting
Phase 2

Perioperative Vitamin C to Reduce Persistent Pain After Total Knee Arthroplasty

Post Operative PainChronic PainKnee Pain Chronic
University Health Network, Toronto400 enrolled3 locationsNCT06123715
Recruiting
Phase 2

Brain-Computer Interface Visualization Training to Optimize Muscle Activation Following Orthopaedic Surgery

Hip arthroscopyTotal Hip Arthroplasty (THA)Total Knee Arthroplasty+1 more
Rush University Medical Center240 enrolled1 locationNCT07020312
Recruiting
Phase 2

Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis

Primary Knee Osteoarthritis
Enlivex Therapeutics Ltd.270 enrolled17 locationsNCT07580716
Recruiting
Phase 2Phase 3

Cannabidiol (CBD) in Pain Reduction for Knee Osteoarthritis

Knee arthritis
NYU Langone Health100 enrolled1 locationNCT05020028
Recruiting
Phase 2

Post-operative Analgesic Effect of Oral Nefopam

Postoperative Pain After a Total Knee Arthroplasty
Hospices Civils de Lyon50 enrolled1 locationNCT04576078
Recruiting
Phase 2

Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 2Phase 3

An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis

Knee Arthritis, Osteoarthritis
Cellcolabs Clinical SPV Limited140 enrolled1 locationNCT07542808
Recruiting
Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 2

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 2

Pain Reprocessing Therapy in Post-Operative Knee Pain

Pain, ChronicKnee Pain Chronic
University of Colorado, Denver110 enrolled2 locationsNCT06800209
Recruiting
Phase 1Phase 2

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Knee Osteoarthritis (Knee OA)Knee osteoarthritis (OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 1Phase 2

The Role of Vitamin K on Knee Osteoarthritis Outcomes

Osteo Arthritis Knee
Boston University55 enrolled1 locationNCT06385275
Recruiting
Phase 2

Losartan to Improve Outcomes After Multi-ligament Knee Injury

Multi-ligament Knee Injury
Brigham and Women's Hospital90 enrolled3 locationsNCT06933706
Recruiting
Phase 2Phase 3

Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA

Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 2

Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty(TKA)

Total Knee Arthroplasty
ScinnoHub Pharmaceutical Co., Ltd.270 enrolled1 locationNCT07127042