Phase 2 Knee Clinical Trials
63 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 63 trials
Recruiting
Phase 1Phase 2
COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty
Total Knee AnthroplastyOsteoarthritis PrimaryBilateral Knee Osteoarthritis+1 more
Unity Health Toronto60 enrolled1 locationNCT06809998
Recruiting
Phase 2
A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain
diabetic neuropathic painChronic Low-back PainOsteoarthritis, Knee
Eli Lilly and Company10,000 enrolled64 locationsNCT05986292
Recruiting
Phase 2
Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 2Phase 3
An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Knee Arthritis, Osteoarthritis
Cellcolabs Clinical SPV Limited140 enrolled1 locationNCT07542808
Recruiting
Phase 2
Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty
Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 2
A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis
Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 2
Pain Reprocessing Therapy in Post-Operative Knee Pain
Pain, ChronicKnee Pain Chronic
University of Colorado, Denver110 enrolled2 locationsNCT06800209
Recruiting
Phase 1Phase 2
Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)
Knee Osteoarthritis (Knee OA)Knee osteoarthritis (OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 1Phase 2
The Role of Vitamin K on Knee Osteoarthritis Outcomes
Osteo Arthritis Knee
Boston University55 enrolled1 locationNCT06385275
Recruiting
Phase 2
Losartan to Improve Outcomes After Multi-ligament Knee Injury
Multi-ligament Knee Injury
Brigham and Women's Hospital90 enrolled3 locationsNCT06933706
Recruiting
Phase 2
Study on BT-114143 Reducing Perioperative Bleeding in Total Knee Arthroplasty（TKA）
Total Knee Arthroplasty
ScinnoHub Pharmaceutical Co., Ltd.270 enrolled1 locationNCT07127042
Recruiting
Phase 2Phase 3
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 2
Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity
Chronic PainOsteoarthritis, Knee
Wake Forest University Health Sciences38 enrolled1 locationNCT04427709
Recruiting
Phase 2
The Safety/Efficacy of hUC Mesenchymal Stem Cells（19#iSCLife®-OA） Therapy for Patients With Osteoarthritis
Osteoarthritis, Knee
Sclnow Biotechnology Co., Ltd.60 enrolled1 locationNCT03383081
Recruiting
Phase 2
The Effect and Safety of Anti-inflammatories and Dextrose Prolotherapy Injections in Treating Knee Osteoarthritis
Knee osteoarthritis (OA)
David Grant U.S. Air Force Medical Center68 enrolled1 locationNCT06911359
Recruiting
Phase 2
Study to Evaluate the Efficacy and Safety of TRL1068 for the Treatment of Prosthetic Joint Infection
Prosthetic Joint Infections of HipProsthetic Joint Infections of Knee
Trellis Bioscience LLC60 enrolled17 locationsNCT06621251
Recruiting
Phase 2
An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint
Osteo Arthritis KneeOsteoarthritis
Ageless Biotech, Inc.400 enrolled1 locationNCT06485843
Recruiting
Phase 1Phase 2
CBD for Knee Osteoarthritis
Osteoarthritis, Knee
University of Florida30 enrolled1 locationNCT06414473
Recruiting
Phase 2
Role of Methotrexate in Ultrasound Proven Synovitis in Primary Knee OA
MethotrexateOsteo Arthritis of the KneeSynovitis of Knee
Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh70 enrolled1 locationNCT07161336
Recruiting
Phase 2
Cannabinoid Interactions With Central and Peripheral Pain Mechanisms in Osteoarthritis of the Knee
Osteoarthritis, KneeOsteoarthritis of the knee
Steven E Harte, PhD200 enrolled1 locationNCT04992624