Phase 4 Knee Clinical Trials
64 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 64 trials
Recruiting
Phase 4
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
SleepKnee Osteoarthritis
University of Miami64 enrolled1 locationNCT06902285
Recruiting
Phase 4
Medrol Dosepak for Outpatient Total Knee Arthroplasty
Total Knee Arthroplasty
Rush University Medical Center420 enrolled1 locationNCT05097976
Recruiting
Phase 4
Methadone in the Management of Post-Operative Pain in Total Knee Replacement
Total Knee Arthroplasty
AdventHealth192 enrolled1 locationNCT07485803
Recruiting
Phase 4
Study to Evaluate a New Cartilage Regeneration Platform for Knee Cartilage Repair
Cartilage Defects of the Knee
ROKIT Healthcare104 enrolled13 locationsNCT07639424
Recruiting
Phase 4
Branched Chain Amino Acids for Sarcopenia in Patients Undergoing Total Knee Arthroplasty
SarcopeniaTotal Knee Arthroplasty
Seoul National University Hospital140 enrolled3 locationsNCT07634523
Recruiting
Phase 4
Flex Appeal: Evaluating the Efficacy of Anesthetic Techniques for Manipulation of Knees Under Anesthesia
Knee Stiffness After Total Knee Arthroplasty
Duke University128 enrolled1 locationNCT07348614
Recruiting
Phase 4
Vancomycin in TKAs
Total Knee Arthroplasty
University of California, San Diego30 enrolled1 locationNCT07282782
Recruiting
Phase 4
Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
Diabetes Mellitus, Type 2Osteoarthritis, Knee
University of Kansas Medical Center120 enrolled1 locationNCT06478186
Recruiting
Phase 4
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
Osteo Arthritis of the Knee
Region Skane200 enrolled1 locationNCT07350252
Recruiting
Phase 4
Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
Knee Osteoarthritis
Northwestern University180 enrolled1 locationNCT06245109
Recruiting
Phase 4
Arthrosamid vs. Steroid for the Management of Knee Osteoarthritis
Osteo Arthritis KneeOsteoarthritisIntraarticular Injection
Cappagh National Orthopaedic Hospital200 enrolled1 locationNCT07489521
Recruiting
Phase 4
Knee Injections for Obese Patients With Knee Arthritis
osteoarthritis of Knee.
Mayo Clinic40 enrolled1 locationNCT06782529
Recruiting
Phase 4
Helping Osteoarthritis Patients to Walk With NSAID
Chronic PainOsteoarthritis, KneeOsteoarthritis, Hip
University Hospital, Clermont-Ferrand55 enrolled1 locationNCT05761015
Recruiting
Phase 4
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
Knee injuriesOpioid UsePain, Postoperative
Sanford Health148 enrolled1 locationNCT03858231
Recruiting
Phase 4
Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty
Osteoarthritis, KneeKnee Pain ChronicArthropathy of Knee
Poznan University of Medical Sciences90 enrolled1 locationNCT07180953
Not Yet Recruiting
Phase 4
TRIAD: Trial for Reducing Infection After Arthroplasty with Dilute Povidone-Iodine
End Stage ArthritisOsteoarthritisTotal Knee Replacement
Australian National University5,460 enrolled69 locationsACTRN12626000076370
Recruiting
Phase 4
Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)
Knee Osteoarthritis
Sunnybrook Health Sciences Centre150 enrolled2 locationsNCT06423716
Recruiting
Phase 4
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Recruiting
Phase 4
Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Anterior Cruciate Ligament InjuriesACL InjuryPost-Traumatic Osteoarthritis of Knee+1 more
Hospital for Special Surgery, New York40 enrolled2 locationsNCT06311513