Phase 4 Knee Clinical Trials
60 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 60 trials
Recruiting
Phase 4
Combination of Nerve Blocks and Local Infiltration Analgesia in Knee Arthroplasty
Osteo Arthritis of the Knee
Region Skane200 enrolled1 locationNCT07350252
Recruiting
Phase 4
Brain-Based and Clinical Phenotyping of Pain Pharmacotherapy in Knee Osteoarthritis
Knee Osteoarthritis
Northwestern University180 enrolled1 locationNCT06245109
Recruiting
Phase 4
Arthrosamid vs. Steroid for the Management of Knee Osteoarthritis
Osteo Arthritis KneeOsteoarthritisIntraarticular Injection
Cappagh National Orthopaedic Hospital200 enrolled1 locationNCT07489521
Recruiting
Phase 4
Magnesium-L-Threonate for Sleep Quality Post-Arthroplasty
SleepKnee Osteoarthritis
University of Miami64 enrolled1 locationNCT06902285
Recruiting
Phase 4
Medrol Dosepak for Outpatient Total Knee Arthroplasty
Total Knee Arthroplasty
Rush University Medical Center420 enrolled1 locationNCT05097976
Recruiting
Phase 4
Knee Injections for Obese Patients With Knee Arthritis
osteoarthritis of Knee.
Mayo Clinic40 enrolled1 locationNCT06782529
Recruiting
Phase 4
Helping Osteoarthritis Patients to Walk With NSAID
Chronic PainOsteoarthritis, KneeOsteoarthritis, Hip
University Hospital, Clermont-Ferrand55 enrolled1 locationNCT05761015
Recruiting
Phase 4
Opioids Versus Non-Opioids Postoperative After Knee Arthroscopic Surgery
Knee injuriesOpioid UsePain, Postoperative
Sanford Health148 enrolled1 locationNCT03858231
Recruiting
Phase 4
Impact of Dexamethasone Route on Pain and Inflammation in iPACK With ACB for Knee Arthroplasty
Osteoarthritis, KneeKnee Pain ChronicArthropathy of Knee
Poznan University of Medical Sciences90 enrolled1 locationNCT07180953
Not Yet Recruiting
Phase 4
TRIAD: Trial for Reducing Infection After Arthroplasty with Dilute Povidone-Iodine
End Stage ArthritisOsteoarthritisTotal Knee Replacement
Australian National University5,460 enrolled69 locationsACTRN12626000076370
Recruiting
Phase 4
Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)
Knee Osteoarthritis
Sunnybrook Health Sciences Centre150 enrolled2 locationsNCT06423716
Recruiting
Phase 4
Nalbuphine Timing Effects on Hemodynamics and Analgesia in Elderly Patients
Postoperative Pain, AcuteHemodynamicsTotal Knee Arthroplasty (TKA)
Qianfoshan Hospital162 enrolled1 locationNCT07271849
Recruiting
Phase 4
Reducing Perioperative Oxidative Stress to Prevent Postoperative Chronic Pain Following Total Knee Arthroplasty
Osteoarthritis, KneeTotal Knee ArthroplastyChronic Postsurgical Pain
Vanderbilt University Medical Center148 enrolled1 locationNCT06083480
Recruiting
Phase 4
A Prospective, Randomized Parallel Group Study of the Efficacy of Vancomycin Administered Through Intraarticular Injection Versus Intraosseous Injection Versus Intravenous Infusion in Patients Undergoing Total Knee Arthroplasty
Total Knee Arthroplasty
University of California, San Diego30 enrolled1 locationNCT07282782
Recruiting
Phase 4
Concentrated Bone Marrow Aspirate in Revision ACL Reconstruction
Anterior Cruciate Ligament InjuriesACL InjuryPost-Traumatic Osteoarthritis of Knee+1 more
Hospital for Special Surgery, New York40 enrolled2 locationsNCT06311513
Not Yet Recruiting
Phase 4
Extended Postoperative Oral Tranexamic Acid In Total Hip and Knee Arthroplasty: A Randomised Controlled Study
OsteoarthritisTotal Hip ArthroplastyTotal Knee Arthroplasty
North Sydney Orthopaedic Research Group200 enrolled1 locationACTRN12625000926437
Recruiting
Phase 4
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
Total Knee Replacement
Christian Candrian159 enrolled1 locationNCT04432012
Recruiting
Phase 4
Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality
Knee Replacement Surgeryhip replacement surgerySleep Quality+3 more
Peking University First Hospital154 enrolled2 locationsNCT05950646
Recruiting
Phase 4
The Perioperative Outcome of Epinephrine Infusion and Tranexamic Acid in Knee Arthroplasty Surgery
blood lossKnee Arthroplasty, TotalKnee Arthritis, Osteoarthritis+3 more
King Abdullah International Medical Research Center80 enrolled1 locationNCT07089251
Recruiting
Phase 4
Knee Osteoarthritis Treatment With Zilretta vs. Kenalog in the Context of Type II Diabetes
Diabetes Mellitus, Type 2Osteoarthritis, Knee
University of Kansas Medical Center120 enrolled1 locationNCT06478186