Phase 2 Liver Cancer Clinical Trials

24 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 24 trials

Recruiting
Phase 2

Y-90 Treatment Response Using Transarterial Radioembolization

Liver CancerHepatocellular CarcinomaPrimary Liver Cancer+3 more
Thomas Jefferson University30 enrolled1 locationNCT07145801
Recruiting
Phase 1Phase 2

GPC3-Targeted T-Cell Therapy (ECT204) in Adults With Advanced HCC

Hepatocellular CarcinomaMetastatic Liver CancerLiver Cancer, Adult+1 more
Eureka Therapeutics Inc.60 enrolled8 locationsNCT04864054
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 1Phase 2

A Study Evaluating the Efficacy and Safety of Multiple Immunotherapy-Based Treatment Combinations in Patients With Advanced Liver Cancers (Morpheus-Liver)

Advanced Liver Cancers
Hoffmann-La Roche518 enrolled33 locationsNCT04524871
Recruiting
Phase 2

68Ga-PSMA-11 PET-directed Radioligand Therapy in Metastatic Hepatocellular Carcinoma (HCC)

Liver CancerHepatocellular CarcinomaMetastatic Liver Cancer
Melissa Lumish10 enrolled1 locationNCT06852820
Recruiting
Phase 1Phase 2

Dual-Target GPC3/B7-H3 CAR-NK Cells for Advanced HCC

Metastatic Liver CancerAdvanced Hepatocellular Carcinoma (HCC)
Beijing Biotech30 enrolled1 locationNCT07500220
Recruiting
Phase 2

Radioembolization With Intra-arterial Angiotensin II to Improve Tumor-absorbed Dose (RADIANT)

Liver Cancer (Locally Advanced or Metastatic)Liver Cancer, Adult
Niek Wijnen15 enrolled1 locationNCT07312292
Recruiting
Phase 2

Riluzole For Preventing Cognitive Dysfunction in Ca Pts Receiving Chemo (REFOCUS): Pilot Trial

Breast CancerLiver CancerColorectal, Cancer+7 more
University of California, Irvine24 enrolled1 locationNCT07447050
Recruiting
Phase 2

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

Liver CancerFibrolamellar CarcinomaHepatocellular Carcinoma, Childhood+1 more
Allison O'Neill, MD18 enrolled5 locationsNCT04134559
Recruiting
Phase 1Phase 2

EBNK-001 Allogeneic NK Cells With Low-Dose IL-15 ± Pembrolizumab in Advanced Solid Tumors

Colorectal, CancerEsophageal CancerOvarian Cancer+12 more
Essen Biotech83 enrolled1 locationNCT07410676
Recruiting
Phase 1Phase 2

Biomarker-Guided Allogeneic Single-Target or Dual-Target CAR-NK Cell Therapy for Advanced Solid Tumors

Breast CancerLiver CancerNon-small Cell Lung Cancer (NSCLC)+10 more
Essen Biotech85 enrolled1 locationNCT07410494
Recruiting
Phase 2

REGULUS: MRI-guided Adaptive SABR for Liver Cancers

Liver CancerLiver MetastasesIntrahepatic Cholangiocarcinoma+1 more
Stanford University62 enrolled1 locationNCT07223307
Recruiting
Phase 1Phase 2

CRISPR-Edited HLA Donor Liver Transplant to Reduce Rejection

Liver CancerLiver MetastasesLiver Cirrhosis+4 more
AMERICAN ORGAN TRANSPLANT AND CANCER RESEARCH INSTITUTE LLC90 enrolled1 locationNCT07053488
Recruiting
Phase 2

Repurposing Riluzole for Cancer-Related Cognitive Impairment: A Pilot Trial

Breast CancerLiver CancerColorectal, Cancer+7 more
University of California, Irvine51 enrolled1 locationNCT06580002
Recruiting
Phase 1Phase 2

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Liver CancerMetastatic Liver CancerLiver Neoplasms+3 more
Eureka Therapeutics Inc.15 enrolled2 locationsNCT04634357
Recruiting
Phase 2

Atezolizumab Plus Bevacizumab Alone or Combined with External Beam Radiotherapy for HCC with Macrovascular Invasion

Liver CancerHepatocellular CarcinomaHepatocellular Cancer+2 more
Asan Medical Center138 enrolled1 locationNCT05992220
Recruiting
Phase 2

Stereotactic Radiosurgery Versus Radiofrequency Ablation for Primary Liver Cancer

Primary Liver Cancer
Tianjin Medical University Cancer Institute and Hospital130 enrolled1 locationNCT06766643
Recruiting
Phase 2

TACE Using Idarubicin Versus Doxorubicin Chemoemulsion in Patients with Hepatocellular Carcinoma

Liver CancerHepatocellular Carcinoma
Seoul National University Hospital128 enrolled1 locationNCT06114082
Recruiting
Phase 2

Checkpoint Inhibitor Combinations Therapy as First Line for HCC Via IT

Liver CancerAntibody
Second Affiliated Hospital of Guangzhou Medical University90 enrolled1 locationNCT06482801
Recruiting
Phase 1Phase 2

Triplex Checkpoint Inhibitors Therapy for Advanced Solid Tumors

Breast CancerLiver CancerColorectal, Cancer+8 more
Second Affiliated Hospital of Guangzhou Medical University100 enrolled1 locationNCT05187338