Phase 4 Management Clinical Trials

26 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 120 of 26 trials

Recruiting
Phase 4

Precision Colchicine Intervention to Suppress Atherosclerosis in TET2 Clonal Hematopoiesis

Clonal Hematopoiesis of Indeterminate PotentialColchicineCoronary Atherosclerosis Management
Shenyang Northern Hospital120 enrolled1 locationNCT07362966
Recruiting
Phase 4

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Opioid analgesiaPostoperative Pain ManagementOphthalmic Surgery
Zhongshan Ophthalmic Center, Sun Yat-sen University204 enrolled3 locationsNCT07269106
Not Yet Recruiting
Phase 4

Magnesium sulfate as an adjunct to levobupivacaine in rectus sheath block for colorectal surgery: a randomized controlled study

perioperative pain management
University Hospital Sestre Milosrdnice60 enrolled1 locationACTRN12626000376347
Recruiting
Phase 4

Suprainguinal Fascia Iliaca Block With vs Without Dexmedetomidine

Postoperative Pain Management
Rhode Island Hospital120 enrolled1 locationNCT07316166
Recruiting
Phase 4

Continous Infusion of Nefopam for Patients Undergoing Pancreatoduodenectomy

Opioid analgesiaPain ManagementMultimodal Analgesia+1 more
Iuliu Hatieganu University of Medicine and Pharmacy93 enrolled1 locationNCT07423650
Recruiting
Phase 4

COMFORT Trial: Complex Obstetric Management With Focused Regional Transversus Abdominis Plane Block

cesarean deliveryPostoperative pain controlperioperative pain management+1 more
University of Tennessee120 enrolled1 locationNCT06925152
Recruiting
Phase 4

The Effect of Multimodal Pain Regimen on Use of Narcotics After Rotator Cuff Tear Repair

Pain ManagementRotator Cuff Repairs
Montefiore Medical Center130 enrolled1 locationNCT07076069
Recruiting
Phase 4

Effect of Lidocaine-Dexmedetomidine on Pain, Inflammation, and Oxidative Stress After Bariatric Surgery.

Postoperative PainPostoperative Adjuvant TreatmentPostoperative Pain Management+4 more
Instituto Mexicano del Seguro Social104 enrolled2 locationsNCT07073846
Recruiting
Phase 4

Efficacy of Methylprednisolone for Pain Control After ACL Repair

Pain ManagementACL Surgery
St. Louis University90 enrolled1 locationNCT07158476
Recruiting
Phase 4

Magnesium and Cramping

Postoperative Pain ManagementHysteroscopyUterine Cramps
Corewell Health East150 enrolled1 locationNCT06745388
Recruiting
Phase 4

Metabolic and Behavioural Effects of CONTRAVE as Potential Mechanisms of Weight Loss in Adults With Obesity

ObesityWeight LossWeight Management+2 more
The Royal's Institute of Mental Health Research40 enrolled3 locationsNCT06809166
Recruiting
Phase 4

Continuous vs. Bolus Administration of NSAIDs After Laparoscopic Surgery for Multimodal Analgesia

Pain ManagementPostoperative CareAnalgesic Drugs+3 more
Federal Research and Clinical Centre of Intensive Care Medicine and Rehabilitology100 enrolled1 locationNCT07070050
Recruiting
Phase 4

The Effect of Intraoperative Intravenous Lidocaine Infusion on Postoperative Pain and Recovery in Children (< 7 Years Old) Undergoing Thoracoscopic Surgery

Pain Management After Surgery
Seoul National University Hospital80 enrolled1 locationNCT06710405
Recruiting
Phase 4

Perioperative Rectal Methadone in Spine Surgery

Post-operative careSpinal surgeryPost-operative Pain Management
Unity Health Toronto40 enrolled1 locationNCT06843174
Completed
Phase 4

Effect of Adding Remifentanil to Thiopental Anaesthesia Induction on Classic Laryngeal Mask Airway Insertion Success: A Randomized Double-Blind Clinical Trial

AnaesthesiologyAnesthesiology Airway management
Firat University School of Medicine Hospital120 enrolled2 locationsACTRN12625000175471
Recruiting
Phase 4

The Utility of Pericapsular Nerve Group (PENG) Block versus Intrathecal Morphine for Postoperative Analgesia in Anterior Approach Total Hip Arthroplasty: A Multicentre Triple Blinded Randomised Controlled Trial

Hip ArthroplastyPain Management
Tim Cheok70 enrolled1 locationACTRN12623001309673
Not Yet Recruiting
Phase 4

Lidocaine Infusion Population Pharmacokinetics Study (LIPPS): determining pharmacokinetics of lidocaine in those undergoing breast reconstructive surgery

Pain Management
Royal Perth Hospital40 enrolled1 locationACTRN12623000240640
Terminated
Phase 4

COntinuous or Bolus Administration of Local Anaesthesia for Thoracic Surgery : a single blinded randomized trial (COBALT Trial)

Pain ManagementThoracic Surgery
Austin Hospital120 enrolled1 locationACTRN12618001626257
Terminated
Phase 4

Efficacy of two methods of scar care for the prevention of abnormal scarring following heart surgery in children.

Paediatric Sternotomy Scar Management
The Children's Hospital at Westmead200 enrolled1 locationACTRN12617000813381
Recruiting
Phase 4

Use of Patient Controlled Analgesics in the management of pain in Orthognathic Surgery – A randomised controlled trial pilot study

Post surgery pain management
Royal Perth Hospital40 enrolled2 locationsACTRN12616000919415