MSA Clinical Trials

19 recruitingLast updated: June 20, 2026

There are 19 actively recruiting msa clinical trials across 10 countries. Studies span Not Applicable, Early Phase 1, Phase 1, Phase 3, Phase 2. Top locations include Leuven, Vlaams-Brabant, Belgium, Hunan, Changsha, China, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


MSA Trials at a Glance

19 actively recruiting trials for msa are listed on ClinicalTrialsFinder across 6 cities in 10 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Leuven, Hunan, and Beijing. Lead sponsors running msa studies include Beijing Tiantan Hospital, Min Zhao,MD, and Bastyr University.

Browse msa trials by phase

Treatments under study

About MSA Clinical Trials

Looking for clinical trials for MSA? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new MSA trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about MSA clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Early Phase 1

Evaluation of [¹⁸F]MODAG-009 PET Imaging in Synucleinopathies

Parkinson DiseaseHealthy AdultMultiple System Atrophy (MSA)
MODAG GmbH13 enrolled1 locationNCT07640555
Recruiting

Multiple System Atrophy Multidisciplinary Clinic

Multiple System Atrophy (MSA)
University of Texas Southwestern Medical Center200 enrolled1 locationNCT03811808
Recruiting
Not Applicable

Efficacy and Safety of Transcranial dIrect Current stiMulation in Multiple System Atrophy-Cerebellar Variant

Multiple System Atrophy - Cerebellar Subtype (MSA-C)
University of Salerno30 enrolled1 locationNCT06821256
Recruiting

Invasive Home Ventilation in Denmark

Spinal Cord Injuries (SCI)Neuromuscular Diseases (NMD)MSA - Multiple System Atrophy+5 more
Rigshospitalet, Denmark450 enrolled1 locationNCT07467187
Recruiting
Phase 1

A Phase I/III Clinical Study to Evaluate NouvNeu001 Injection for Multiple System Atrophy

Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
iRegene Therapeutics Co., Ltd.9 enrolled1 locationNCT07289477
Recruiting
Not Applicable

Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders

PSP - Progressive Supranuclear PalsyAlzheimer Dementia (AD)MSA - Multiple System Atrophy+7 more
Universitaire Ziekenhuizen KU Leuven300 enrolled1 locationNCT07509125
Recruiting

Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease

Parkinson DiseaseMSA - Multiple System AtrophyLewy Body Dementia (LBD)+2 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta180 enrolled3 locationsNCT06846658
Recruiting
Phase 1

A Study to Assess the Effect of Acid-Reducing Medicines on ATH434 in Healthy Volunteers

Multiple System Atrophy (MSA)
Alterity Therapeutics Limited12 enrolled1 locationACTRN12626000320358
Recruiting
Phase 3

MSA-01 in Multiple System Atrophy

Multiple System Atrophy (MSA)
Tokyo University140 enrolled12 locationsNCT07446894
Recruiting

The CurePSP Genetics Program

Multiple System Atrophy, Parkinsonian TypeMultiple System Atrophy, Cerebellar TypeMultiple System Atrophy+15 more
Massachusetts General Hospital1,000 enrolled1 locationNCT06647641
Recruiting
Early Phase 1

[18F]ACI-15916 PET in α-synucleinopathies

Parkinson's Disease (PD)Multiple System Atrophy (MSA)Dementia With Lewy Bodies (DLB)
AC Immune SA46 enrolled1 locationNCT06891703
Recruiting
Not Applicable

Epidural Electrical Stimulation to Support Hemodynamic Management in Individuals With Parkinson's Disease

Parkinson's DiseaseHypotension SymptomaticOrthostatic Hypotension, Dysautonomic+2 more
Ecole Polytechnique Fédérale de Lausanne5 enrolled1 locationNCT06920134
Recruiting
Early Phase 1

The Study of Safety and Preliminary Efficacy of Aleeto in Patients With MultIple System Atrophy

Multiple System Atrophy (MSA)Multiple System Atrophy - Parkinsonian Subtype (MSA-P)
Beijing Tiantan Hospital20 enrolled1 locationNCT06765733
Recruiting
Not Applicable

Neurologic Stem Cell Treatment Study

Cognitive ImpairmentDementiaTraumatic Brain Injury+23 more
MD Stem Cells500 enrolled3 locationsNCT02795052
Recruiting

AI-Enhanced Optimization of Acute Levodopa Challenge Test

Corticobasal Degeneration (CBD)Progressive Supranuclear Palsy (PSP)Parkinson Disease (PD)+4 more
Beijing Tiantan Hospital2,000 enrolled1 locationNCT06949865
Recruiting

Targeted Α-synuclein PET Imaging in the Diagnosis of Multiple System Atrophy

Multiple System Atrophy - Parkinsonian Subtype (MSA-P)Multiple System Atrophy - Cerebellar Subtype (MSA-C)
Min Zhao,MD90 enrolled1 locationNCT06890377
Recruiting

TSPO PET in the Evaluation of Neuroinflammation in Patients with Multiple System Atrophy

Multiple System Atrophy - Parkinsonian Subtype (MSA-P)Multiple System Atrophy - Cerebellar Subtype (MSA-C)
Min Zhao,MD90 enrolled1 locationNCT06890390
Recruiting
Phase 2Phase 3

[18F]-MFBG Versus [123I]-MIBG and [18F]-PE2I in PD vs. MSA and DLB vs. AD

Alzheimer DiseaseParkinson DiseaseDementia With Lewy Bodies+1 more
prof. dr. Koen Van Laere113 enrolled2 locationsNCT06120049
Recruiting

Modifiable Variables in Parkinsonism (MVP)

Corticobasal DegenerationDementia With Lewy BodiesProgressive Supranuclear Palsy+6 more
Bastyr University2,000 enrolled1 locationNCT02194816