Muscular Diseases Clinical Trials

40 recruitingLast updated: June 18, 2026

There are 40 actively recruiting muscular diseases clinical trials across 23 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1. Top locations include Dallas, Texas, United States, New York, New York, United States, London, United Kingdom. Updated daily from ClinicalTrials.gov.


Muscular Diseases Trials at a Glance

40 actively recruiting trials for muscular diseases are listed on ClinicalTrialsFinder across 6 cities in 23 countries. The largest study group is Not Applicable with 13 trials, with the heaviest enrollment activity in Dallas, New York, and London. Lead sponsors running muscular diseases studies include Assistance Publique - Hôpitaux de Paris, Guy's and St Thomas' NHS Foundation Trust, and Boston Children's Hospital.

Browse muscular diseases trials by phase

Treatments under study

About Muscular Diseases Clinical Trials

Looking for clinical trials for Muscular Diseases? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Muscular Diseases trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Muscular Diseases clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 40 trials

Recruiting
Phase 2

Assessment of Volume-targeted Ventilation in Patients With Neuromuscular Disease

Neuromuscular Diseases
Guy's and St Thomas' NHS Foundation Trust30 enrolled2 locationsNCT06339580
Recruiting

Investigating Health Related Quality of Life in Patients With Chronic Respiratory Failure

Chronic Obstructive Pulmonary DiseaseRespiratory FailureNeuromuscular Diseases+1 more
Guy's and St Thomas' NHS Foundation Trust200 enrolled1 locationNCT04236726
Recruiting
Not Applicable

Optimisation of Mechanical Insufflation:Exsufflation

Neuromuscular Diseases
Guy's and St Thomas' NHS Foundation Trust30 enrolled1 locationNCT04163198
Recruiting
Phase 2

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Duchenne Muscular DystrophyDMDNeuromuscular Diseases+2 more
Satellos Bioscience, Inc.51 enrolled21 locationsNCT07287189
Recruiting
Not Applicable

Does the Coaching Function Improve the Learning of Mechanical In-exsufflation (MI-E) in Paediatric Subjects?

Neuromuscular DiseasesCoughAirway Clearance Impairment
Cliniques universitaires Saint-Luc- Université Catholique de Louvain40 enrolled1 locationNCT06190431
Recruiting

Northwestern Neuromuscular Disease Biorepository

Neuromuscular Diseases (NMD)
Northwestern University2,500 enrolled1 locationNCT07477509
Recruiting
Phase 3

Efficacy, Safety, and Tolerability of Zeleciment Rostudirsen (DYNE-251) Administered Intravenously Every 4 Weeks in Ambulatory Participants With Duchenne Muscular Dystrophy (FORZETTO)

Muscular Dystrophy, DuchenneDMDNeuromuscular Diseases (NMD)+10 more
Dyne Therapeutics90 enrolled1 locationNCT07608432
Recruiting
Not Applicable

Non-invasive BCI-controlled Assistive Devices

Traumatic Brain InjuryHealthyMovement Disorders+6 more
University of Texas at Austin100 enrolled1 locationNCT05183152
Recruiting

Invasive Home Ventilation in Denmark

Spinal Cord Injuries (SCI)Neuromuscular Diseases (NMD)MSA - Multiple System Atrophy+5 more
Rigshospitalet, Denmark450 enrolled1 locationNCT07467187
Recruiting
Phase 3

A Phase 3 Study of NTLA-2001 in ATTRv-PN

Nervous system diseasePeripheral nervous system diseaseAmyloidosis+17 more
Intellia Therapeutics60 enrolled14 locationsNCT06672237
Recruiting
Not Applicable

Respiratory Muscles and Work of Breathing in Children

Lung DiseasesNeuromuscular DiseasesScoliosis+4 more
Assistance Publique - Hôpitaux de Paris550 enrolled1 locationNCT05051254
Recruiting

Spastic Paraplegia - Centers of Excellence Research Network

Neuromuscular DiseasesPrimary Lateral SclerosisHereditary Spastic Paraplegia+6 more
Boston Children's Hospital100 enrolled11 locationsNCT06553976
Recruiting
Not Applicable

Effects of Whole-body Electrical Muscle Stimulation Exercise on Adults With Neuromuscular Disease

Myasthenia GravisAmyotrophic Lateral SclerosisNeuromuscular Diseases (NMD)+15 more
University of Missouri-Columbia50 enrolled1 locationNCT07478172
Recruiting
Phase 1

A Phase 1 Study of Anitocabtagene Autoleucel for the Treatment of Subjects With Non-oncology Plasma Cell-related Diseases

Myasthenia GravisMuscle WeaknessAutoimmune Diseases+4 more
Arcellx, Inc.30 enrolled13 locationsNCT06626919
Recruiting

Measuring Physical Activity With ActivPal

Neuromuscular Diseases
Columbia University40 enrolled1 locationNCT06084026
Recruiting

A Prospective Natural History and Outcome Measure Discovery Study of Charcot-Marie-Tooth Disease, Type 4J

Peripheral NeuropathyNeuro-Degenerative DiseaseNeuromuscular Diseases
Elpida Therapeutics SPC20 enrolled3 locationsNCT06151600
Recruiting
Not Applicable

EMMVIES : Walking Training at Home in VIrtual Reality for Children With Chronic Illnesses Impacting Physical Health

ObesityVirtual RealityCerebral Palsy+4 more
University Hospital, Angers30 enrolled1 locationNCT07021638
Recruiting
Not Applicable

The Effect of a Muscle-mimicking, Fabric-type Shoulder Orthosis on Functional Movements of the Upper Limb in Patients With Neuromuscular Disorder

Upper ExtremityMuscular Dystrophy, DuchenneNeuromuscular Diseases (NMD)+6 more
Seoul National University Hospital30 enrolled1 locationNCT06363357
Recruiting
Not Applicable

Non-Invasive Respiratory Monitor

Healthy VolunteersNeuromuscular Diseases
Nemours Children's Clinic20 enrolled1 locationNCT02851043
Recruiting

Polygraphy at Home for Neuromuscular Patients Under Non-invasive Mechanical Ventilation

Neuromuscular Diseases
Assistance Publique - Hôpitaux de Paris25 enrolled1 locationNCT05785637