Phase 3 Neck Cancer Clinical Trials

18 recruitingPhase 3

What is a Phase 3 trial?

Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.

Showing 118 of 18 trials

Recruiting
Phase 3

Palliative Steroeotactic Body Radiotherapy vs Palliative Standard Radiotherapy in Patients With Advanced Head and Neck Cancer

Advanced Head and Neck Cancer
Canadian Cancer Trials Group196 enrolled8 locationsNCT06641791
Recruiting
Phase 2Phase 3

Trop2-targeted immunoPET Imaging of Solid Tumors

Liver CancerOvarian CancerCervical Cancer+11 more
RenJi Hospital400 enrolled1 locationNCT06851663
Recruiting
Phase 2Phase 3

A Clinical Trial Investigating the Safety, Tolerability, and Therapeutic Effects of BNT113 in Combination With Pembrolizumab Versus Pembrolizumab Alone for Patients With a Form of Head and Neck Cancer Positive for Human Papilloma Virus 16 and Expressing the Protein PD-L1

Unresectable Head and Neck Squamous Cell CarcinomaMetastatic Head and Neck CancerRecurrent Head and Neck Cancer
BioNTech SE350 enrolled195 locationsNCT04534205
Recruiting
Phase 3

Study Comparing Ivonescimab Alone or Ivonescimab in Combination With Ligufalimab Versus Pembrolizumab for the Treatment of SCCHN

Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
Groupe Oncologie Radiotherapie Tete et Cou780 enrolled1 locationNCT07264075
Recruiting
Phase 2Phase 3

Trial Evaluating Hypo-fractionated Accelerated Versus Conventional Fractionated Adjuvant RT in Head & Neck Malignancies

Squamous Cell Carcinoma Head and Neck Cancer (HNSCC)
All India Institute of Medical Sciences369 enrolled1 locationNCT07573956
Recruiting
Phase 2Phase 3

A Trial Evaluating Omission of Radiotherapy to Regional Lymphatic's

Head and Neck Cancer
All India Institute of Medical Sciences396 enrolled1 locationNCT07528495
Recruiting
Phase 3

Postoperative Radiotherapy Combined With Nimotuzumab Followed by Benmelstobart in High-Risk Patients With Head and Neck Squamous Cell Carcinoma

Head & Neck CancerPostoperative Adjuvant TreatmentHead & Neck Squamous Cell Carcinoma
Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University370 enrolled1 locationNCT07445048
Recruiting
Phase 3

Development and Application of a Nurse-Led Preemptive Symptom Management Protocol for Head and Neck Cancer Patients Undergoing Radiation Therapy

Head and Neck Cancer
West China Hospital170 enrolled1 locationNCT07467083
Recruiting
Phase 3

Compare Radiotherapy Plus Nimotuzumab Versus Radiotherapy Alone in Platinum-ineligible Patients With Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Head & Neck CancerHead & Neck Squamous Cell Carcinoma
Shandong Cancer Hospital and Institute335 enrolled1 locationNCT07333274
Recruiting
Phase 2Phase 3

Contrast-enhanced Ultrasound for Sentinel Node Detection

Breast CancerMelanomaHead & Neck Cancer
The Netherlands Cancer Institute91 enrolled1 locationNCT07310758
Recruiting
Phase 3

Addressing Taste Dysfunction With Miraculin in Head and Neck Cancer Patients Receiving Radiation Therapy

Head and Neck CancerTaste Dysfunction
University of California, San Francisco40 enrolled1 locationNCT05273307
Recruiting
Phase 3

Study Comparing the Standard Administration of IO Versus the Same IO Administered Each 3 Months in Patients in Response After 6 Months of Standard IO

Triple-Negative Breast CancerCervical CancerUrothelial Carcinoma+12 more
UNICANCER646 enrolled40 locationsNCT05078047
Recruiting
Phase 3

Stereotactic Boost and Short-course Radiation Therapy for Oropharynx Cancer

Head and Neck CancerOropharynx CancerHuman Papilloma Virus
Centre hospitalier de l'Université de Montréal (CHUM)360 enrolled2 locationsNCT04178174
Recruiting
Phase 2Phase 3

Trans-Artery/Intra-Tumor Infusion of Checkpoint Inhibitors Plus Chemodrug for Immunotherapy of Advanced Solid Tumors

Breast CancerOvarian CancerCervical Cancer+7 more
Second Affiliated Hospital of Guangzhou Medical University200 enrolled1 locationNCT03755739
Recruiting
Phase 3

Optimising Patient Experience in Head and Neck Radiotherapy

Head and Neck Cancer
Irish Research Radiation Oncology Group201 enrolled1 locationNCT06327139
Recruiting
Phase 3

Efficacy and safety of local anesthesia in patients with head and neck tumors undergoing percutaneous endoscopic gastrostomy (PEG): Lidocaine versus ropivacaine - Prospective, randomized, double blind study

Percutaneous endoscopic gastrostomy (PEG)CancerHead and Neck cancer patients
Instituto Português de Oncologia de Lisboa de Francisco Gentil, EPE30 enrolled1 locationACTRN12618000713291
Terminated
Phase 2Phase 3

Does Mepitel Film decrease skin reactions caused by radiation therapy in head and neck cancer patients?

Acute radiation-induced skin reactionsHead and Neck Cancer
Otago University86 enrolled2 locationsACTRN12616000725460
Terminated
Phase 3

Hyperbaric Oxygen Therapy for Radiation Induced Xerostomia (Dry Mouth)

Soft tissue radiation injury to salivary glands (xerostomia)Head and Neck Cancer
Dr S Sherlock60 enrolled1 locationACTRN12612000084886