Nephrotic Syndrome Clinical Trials

19 recruiting

Nephrotic Syndrome Trials at a Glance

44 actively recruiting trials for nephrotic syndrome are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 9 trials, with the heaviest enrollment activity in Hangzhou, Philadelphia, and New Hyde Park. Lead sponsors running nephrotic syndrome studies include The Children's Hospital of Zhejiang University School of Medicine, Mao Jianhua, and Assistance Publique - Hôpitaux de Paris.

Browse nephrotic syndrome trials by phase

Treatments under study

About Nephrotic Syndrome Clinical Trials

Looking for clinical trials for Nephrotic Syndrome? There are currently 19 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Nephrotic Syndrome trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Nephrotic Syndrome clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 44 trials

Recruiting

Immune System Related Kidney Disease

Kidney DiseaseNephrotic Syndrome
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)2,000 enrolled1 locationNCT00001979
Recruiting
Not Applicable

A Smart Phone Application to Improve Adoption of the 2024 Kidney Disease Improving Global Outcomes (KDIGO) Chronic Kidney Disease (CKD) Guidelines

Chronic Kidney DiseaseProteinuriaBlood Pressure Control+2 more
St. James's Hospital, Ireland80 enrolled2 locationsNCT07561957
Recruiting
Phase 2

Rituximab Plus Cyclosporine in Idiopathic Membranous Nephropathy

Autoimmune DiseaseProteinuriaGlomerular Disease+2 more
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)30 enrolled2 locationsNCT00977977
Recruiting
Not Applicable

taVNS for FRNS in Children

Nephrotic Syndrome in ChildrenFocal Segmental GlomerulosclerosisMinimal Change Disease
Northwell Health30 enrolled2 locationsNCT05588063
Recruiting
Not Applicable

A Pilot Trial of taVNS for SRNS in Children (kidNEY-VNS)

Nephrotic Syndrome in ChildrenFocal Segmental GlomerulosclerosisMinimal Change Disease
Northwell Health10 enrolled2 locationsNCT05583942
Recruiting
Not Applicable

SLIT ABS: Study on Patients With Autoimmune Podocytopathy

Minimal Change Nephrotic SyndromeNephrotic Syndrome With Edema (Diagnosis)
Meyer Children's Hospital IRCCS50 enrolled14 locationsNCT07516964
Recruiting
Early Phase 1

Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07507201
Recruiting
Not Applicable

Multitarget Strategy for Primary Podocytopathies

Nephrotic Syndrome
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico150 enrolled2 locationsNCT06718894
Recruiting

A National Prospective Cohort of Patients With Idiopathic Nephrotic Syndrome Beginning in Childhood.

Idiopathic Nephrotic Syndrome
University Hospital, Limoges1,180 enrolled48 locationsNCT04207580
Recruiting
Phase 2

A Study of the Safety, Tolerability, Pharmacokinetics and Efficacy of Treatment With AP1189 in Patients With iMN and Severe Proteinuria

Nephrotic Syndrome Due to Idiopathic Membranous NephropathySevere Proteinuria Due to Idiopathic Membranous Nephropathy
SynAct Pharma Aps23 enrolled1 locationNCT04456816
Recruiting
Phase 2

A Study of Anti-CD38 Monoclonal Antibody (SG301) Subcutaneous Injection in Children With Nephrotic Syndrome With Frequent Relapses or Steroid Dependence

Nephrotic Syndrome in Children
Mao Jianhua30 enrolled1 locationNCT07087314
Recruiting
Not Applicable

NEPTUNE Match Study

Nephrotic Syndrome in ChildrenAlport SyndromeFocal Segmental Glomerulosclerosis+6 more
University of Michigan375 enrolled16 locationsNCT04571658
Recruiting
Phase 2

Belimumab With Rituximab for Primary Membranous Nephropathy

Membranous NephropathyNephrotic Syndrome
National Institute of Allergy and Infectious Diseases (NIAID)58 enrolled20 locationsNCT03949855
Recruiting
Phase 1

CAR T-cell Therapy Targeting CD19 and BCMA in Patients With B Cell Mediated Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07305116
Recruiting
Phase 2

Atacicept in Multiple Glomerular Diseases

IgANNephrotic SyndromeFSGS+2 more
Vera Therapeutics, Inc.200 enrolled1 locationNCT06983028
Recruiting

Interview Study of Adult and Child Patients and Parents of Children With Swelling Due to Nephrotic Syndrome.

EdemaNephrotic Syndrome in ChildrenMembranous Nephropathy+10 more
University of Michigan150 enrolled1 locationNCT05505500
Recruiting
Phase 2

Dupilumab Therapy in Nephrotic Syndrome in Children

Nephrotic Syndrome in ChildrenNephrotic Syndrome Steroid-Dependent
National University Hospital, Singapore66 enrolled2 locationsNCT07091175
Recruiting
Early Phase 1

Anti-CD19/BCMA CAR-NK Cells in Patients With B Cell Mediated Autoimmune Disease

Autoimmune DiseasesSystemic Lupus ErthematosusMulti-Drug Resistant Nephrotic Syndrome+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT06792799
Recruiting
Not Applicable

Diuretic Tuner Clinical Decision Support

EdemaChronic Kidney DiseasesHypervolemia+1 more
University of Texas Southwestern Medical Center30 enrolled1 locationNCT04759274
Recruiting

The FOrMe Registry (The German Focal Segmental Glomerulosclerosis and Minimal Change Disease Registry)

Minimal Change DiseaseGlomerulosclerosis, Focal SegmentalIdiopathic Nephrotic Syndrome
Prof. Dr. Paul Brinkkoetter500 enrolled12 locationsNCT03949972