Nervous system disease Clinical Trials

68 recruitingLast updated: May 21, 2026

There are 68 actively recruiting nervous system disease clinical trials across 33 countries. Studies span Not Applicable, Phase 2, Phase 3, Phase 1, Phase 4. Top locations include Pittsburgh, Pennsylvania, United States, Bethesda, Maryland, United States, Los Angeles, California, United States. Updated daily from ClinicalTrials.gov.


Nervous system disease Trials at a Glance

68 actively recruiting trials for nervous system disease are listed on ClinicalTrialsFinder across 6 cities in 33 countries. The largest study group is Not Applicable with 31 trials, with the heaviest enrollment activity in Pittsburgh, Bethesda, and Los Angeles. Lead sponsors running nervous system disease studies include Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA), Jorge Gonzalez-Martinez, and Kessler Foundation.

Browse nervous system disease trials by phase

About Nervous system disease Clinical Trials

Looking for clinical trials for Nervous system disease? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Nervous system disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Nervous system disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 68 trials

Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled7 locationsNCT07326566
Recruiting
Phase 2Phase 3

Post-thrombectomy Intra-arterial Tenecteplase for Acute manaGement of Non-retrievable Thrombus and No-reflow in Emergent Stroke

Central Nervous System DiseasesCerebrovascular DisordersIschemic Stroke, Acute+1 more
University of Melbourne462 enrolled12 locationsNCT05892510
Recruiting
Phase 1

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting

Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology

Nervous System Diseases (C10 Unique ID D009422)
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT06203626
Recruiting
Not Applicable

Video Call Assisted Assessment of Acute Stroke

Brain DiseasesCentral Nervous System DiseasesStroke+3 more
University of Southern Denmark512 enrolled1 locationNCT06570681
Recruiting
Not Applicable

Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke

Cardiovascular DiseasesCentral Nervous System DiseasesStroke+2 more
Jorge Gonzalez-Martinez10 enrolled1 locationNCT06303869
Recruiting

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

Multiple SclerosisCentral Nervous System Disease
National Institute of Allergy and Infectious Diseases (NIAID)2,400 enrolled1 locationNCT00794352
Recruiting
Not Applicable

Study to Evaluate the Efficacy and Safety of ATNC-MDD V1(TMS With Cognitive Training) in Mild Alzheimer's Dementia

DementiaBrain DiseasesCentral Nervous System Diseases+5 more
Advanced Technology & Communications180 enrolled11 locationsNCT06088121
Recruiting
Not Applicable

Functional Near-infrared Spectroscopy in Unconscious Patients

Nervous System DiseasesHealthy Subjects
Emanuela Keller30 enrolled2 locationsNCT04746820
Recruiting
Not Applicable

Intra-arterial Thrombolysis for Acute Ischemic Stroke With Medium Vessel Occlusion

Brain DiseasesStrokeCerebrovascular Disorders+5 more
The Second Hospital of Anhui Medical University282 enrolled6 locationsNCT07185022
Recruiting
Phase 3

A Phase 3 Study of NTLA-2001 in ATTRv-PN

Nervous system diseasePeripheral nervous system diseaseAmyloidosis+17 more
Intellia Therapeutics60 enrolled14 locationsNCT06672237
Recruiting

Study of Inherited Neurological Disorders

Peripheral nervous system diseaseMotor Neuron DiseaseMuscular Dystrophy+1 more
National Institute of Neurological Disorders and Stroke (NINDS)3,500 enrolled2 locationsNCT00004568
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Not Applicable

Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation

Central Nervous System DiseasesStrokeCerebrovascular Disorders
Chang Gung Memorial Hospital45 enrolled1 locationNCT05903235
Recruiting

Collection of Biological Samples From Patients With Rare Neurological Diseases

Nervous System Diseases
University Hospital, Toulouse1,000 enrolled1 locationNCT04698421
Recruiting
Not Applicable

Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application

Brain DiseasesCentral Nervous System DiseasesDepression+2 more
Centre Hospitalier Charles Perrens, Bordeaux200 enrolled1 locationNCT03678194
Recruiting
Not Applicable

Basic and Clinical Study of Cardiac Ganglion Catheter Ablation for the Treatment of Significant Bradycardia

Autonomic Nervous System DiseasesSymptomatic Bradycardia
Beijing Anzhen Hospital188 enrolled1 locationNCT07468383
Recruiting
Not Applicable

Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome

Postural Orthostatic tachycardia SyndromeFunctional Gastrointestinal DisordersAutonomic Nervous System Disease+2 more
Medical College of Wisconsin90 enrolled1 locationNCT05212129
Recruiting

Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

COPDSympathetic Nervous System DiseasesCatecholamine; Overproduction
RWTH Aachen University135 enrolled1 locationNCT04849806