Nervous system disease Clinical Trials

1 recruiting

Frequently Asked Questions

Common questions about Nervous system disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 61 trials

Recruiting

Ultra-Low Field (ULF) Point-of-Care (POC) MRI System for Brain Morphology and Pathology

Nervous System Diseases (C10 Unique ID D009422)
National Institute of Neurological Disorders and Stroke (NINDS)200 enrolled1 locationNCT06203626
Recruiting

Comprehensive Multimodal Analysis of Neuroimmunological Diseases of the Central Nervous System

Multiple SclerosisCentral Nervous System Disease
National Institute of Allergy and Infectious Diseases (NIAID)2,400 enrolled1 locationNCT00794352
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting
Phase 2

Study of Silevertinib With Temozolomide for the Treatment of Newly Diagnosed GBM With Unmethylated MGMT and EGFRvIII

Central Nervous System DiseasesBrain CancerGlioblastoma Multiforme (GBM)+4 more
Black Diamond Therapeutics, Inc.162 enrolled2 locationsNCT07326566
Recruiting
Not Applicable

Mixed Reality and Virtual Reality Technology With Mirror Therapy for Stroke Rehabilitation

Central Nervous System DiseasesStrokeCerebrovascular Disorders
Chang Gung Memorial Hospital45 enrolled1 locationNCT05903235
Recruiting

Collection of Biological Samples From Patients With Rare Neurological Diseases

Nervous System Diseases
University Hospital, Toulouse1,000 enrolled1 locationNCT04698421
Recruiting
Not Applicable

Treating Depression on a Day-to-day Basis: Development of a Tool for Physicians Based on a Smartphone Application

Brain DiseasesCentral Nervous System DiseasesDepression+2 more
Centre Hospitalier Charles Perrens, Bordeaux200 enrolled1 locationNCT03678194
Recruiting
Not Applicable

Basic and Clinical Study of Cardiac Ganglion Catheter Ablation for the Treatment of Significant Bradycardia

Autonomic Nervous System DiseasesSymptomatic Bradycardia
Beijing Anzhen Hospital188 enrolled1 locationNCT07468383
Recruiting
Phase 1

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

NeoplasmsNeoplasms by SiteBrain Diseases+30 more
M.D. Anderson Cancer Center24 enrolled3 locationsNCT03911388
Recruiting
Phase 1Phase 2

Study of Abemaciclib and Elacestrant in Participants With Brain Metastasis Due to ER+/HER-2- Breast Cancer

Breast NeoplasmsBreast DiseasesNeoplasms+5 more
Stemline Therapeutics, Inc.73 enrolled86 locationsNCT05386108
Recruiting

Sympathetic Nerve Activity Predictors in Patients With Chronic Obstructive Pulmonary Disease

COPDSympathetic Nervous System DiseasesCatecholamine; Overproduction
RWTH Aachen University135 enrolled1 locationNCT04849806
Recruiting
Not Applicable

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+7 more
University Hospital, Bonn130 enrolled1 locationNCT07324330
Recruiting
Not Applicable

Effects of the COTID (Community Occupational Therapist in Dementia) Program and Usual Occupational Therapy Care on Recurrence of Falls at 12 Months in Elderly People With Neurocognitive Disorders Who Had Been Hospitalized for Falls, After Their Return Home

Nervous System Diseases
University Hospital, Limoges76 enrolled1 locationNCT06237218
Recruiting
Not Applicable

Gravity Stent-Retriever System For Reperfusion Of Large Vessel Occlusion Stroke Trial

Cardiovascular DiseasesBrain DiseasesCentral Nervous System Diseases+5 more
Gravity Medical Technology, INC100 enrolled11 locationsNCT06249776
Recruiting
Not Applicable

Investigating the Feasibility of Combining Virtual Reality and Bilateral Transcranial Direct Stimulation to Improve Upper Limb Recovery in Patients With Stroke

Brain DiseasesCentral Nervous System DiseasesStroke+2 more
King Saud University100 enrolled1 locationNCT07288385
Recruiting
Not Applicable

Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function

Traumatic Brain InjuryStrokeBrain Disease+4 more
Jorge Gonzalez-Martinez60 enrolled1 locationNCT07056348
Recruiting
Phase 4

Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients

ConfusionCognitive DysfunctionMolecular Mechanisms of Pharmacological Action+14 more
Sunnybrook Health Sciences Centre2,400 enrolled8 locationsNCT04289142
Recruiting

Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation

Brain DiseasesCentral Nervous System DiseasesAtrial Fibrillation+11 more
Insel Gruppe AG, University Hospital Bern500 enrolled1 locationNCT06954610
Recruiting
Not Applicable

Clinical Evaluation of EEG Device for the Triage of Stroke Patients in the Ambulance

Cardiovascular DiseasesBrain DiseasesCentral Nervous System Diseases+5 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)275 enrolled1 locationNCT06871969
Recruiting
Not Applicable

Video Call Assisted Assessment of Acute Stroke

Brain DiseasesCentral Nervous System DiseasesStroke+3 more
University of Southern Denmark512 enrolled1 locationNCT06570681