Neurodegenerative Disease Clinical Trials

8 recruiting

Neurodegenerative Disease Trials at a Glance

41 actively recruiting trials for neurodegenerative disease are listed on ClinicalTrialsFinder across 6 cities in 22 countries. The largest study group is Not Applicable with 14 trials, with the heaviest enrollment activity in Hefei, Tianjin, and Exeter. Lead sponsors running neurodegenerative disease studies include Tianjin Medical University, University of Exeter, and Center for Eye Research Australia.

Browse neurodegenerative disease trials by phase

Treatments under study

About Neurodegenerative Disease Clinical Trials

Looking for clinical trials for Neurodegenerative Disease? There are currently 8 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Neurodegenerative Disease trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Neurodegenerative Disease clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 41 trials

Recruiting

The Neurodevelopmental and Behavioral Phenotyping Screening Protocol

AutismNeurologic DisordersNeurodegenerative Disease+1 more
National Institute of Mental Health (NIMH)5,000 enrolled1 locationNCT00271622
Recruiting
Not Applicable

Retinal Hyperspectral Imaging in Neurodegenerative Diseases

DementiaAlzheimer DiseaseParkinson Disease+5 more
Center for Eye Research Australia930 enrolled1 locationNCT07545473
Recruiting
Phase 3

A Study of Donanemab (LY3002813) in Participants With Early Symptomatic Alzheimer's Disease (TRAILBLAZER-ALZ 5)

DementiaBrain DiseasesCentral Nervous System Diseases+6 more
Eli Lilly and Company1,500 enrolled141 locationsNCT05508789
Recruiting

Exploring the Olfactory Mucosa, Blood and Urine for the Identification of Early Biomarkers of Parkinson's Disease, Atypical Parkinsonisms and Neurocognitive Disorders Due to Lewy Body Disease

Parkinson DiseaseMSA - Multiple System AtrophyLewy Body Dementia (LBD)+2 more
Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta180 enrolled3 locationsNCT06846658
Recruiting
Not Applicable

Dyadic Mindfulness for People With Parkinson's Disease and Their Caregivers

MindfulnessMovement DisordersCaregivers+4 more
The University of Hong Kong200 enrolled1 locationNCT06821230
Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

Movement DisordersMotor Neuron DiseaseHereditary Spastic Paraplegia+3 more
Boston Children's Hospital200 enrolled1 locationNCT05354622
Recruiting
Phase 2

Allopregnanolone Regenerative Therapeutic for Mild Alzheimer's Disease

Alzheimer DementiaLate Onset Alzheimer DiseaseNeurodegenerative Diseases
University of Arizona100 enrolled10 locationsNCT04838301
Recruiting
Not Applicable

Feasibility of Wearables in Dementia Care in Rural Taiwan

Circadian RhythmAlzheimer's DementiaNeuropsychiatric Symptoms Related to Neurodegenerative Disease+2 more
China Medical University Hospital20 enrolled1 locationNCT07249918
Recruiting
Not Applicable

Deciphering the Effect of Moderate Wine Consumption on Healthy Aging Through Postprandial Extracellular Vesicles.

ObesityMetabolic SyndromeInflammation+5 more
University of Seville8 enrolled1 locationNCT07361887
Recruiting
Not Applicable

Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity

Brain DiseasesCentral Nervous System DiseasesParkinson Disease+7 more
University Hospital, Bonn130 enrolled1 locationNCT07324330
Recruiting

[18F]NIDF PET Imaging in Tau-related Diseases

Alzheimer s DiseaseTauopathiesNeurodegenerative Disease
Tianjin Medical University20 enrolled2 locationsNCT07306598
Recruiting
Not Applicable

Mindfulness Walking Intervention to Enhance Resilience (iWalk)

MindfulnessNeurodegenerative DiseaseEEG+1 more
University of Illinois at Urbana-Champaign90 enrolled1 locationNCT07285954
Recruiting
Not Applicable

Cognitive Reserve and Response to Speech-Language Intervention in Bilingual Speakers With Primary Progressive Aphasia

DementiaAlzheimer DiseaseCommunication Disorders+11 more
University of Texas at Austin60 enrolled3 locationsNCT05741853
Recruiting

Passive Sensor Identification of Digital Biomarkers to Assess Effects of Orally Administered Nicotinamide Riboside

Cognitive ImpairmentDementiaCognitive Dysfunction+7 more
Mclean Hospital40 enrolled1 locationNCT05245903
Recruiting
Phase 2Phase 3

PET Tau - Neurodegenerative Disease Imaging

Neurodegenerative Disease
University of Pennsylvania300 enrolled1 locationNCT03143374
Recruiting

Molecular and Functional Imaging in Monogenic PD.

Parkinson DiseaseNeurodegenerative DiseasesNervous System Disorder+2 more
University of Exeter45 enrolled1 locationNCT05518617
Recruiting

Molecular Imaging of Inflammation in Parkinson's Disease Using LPS and TSPO-PET/MR

Parkinson DiseaseNeurodegenerative DiseasesREM Sleep Behavior Disorder (iRBD)
University of Exeter30 enrolled1 locationNCT05205291
Recruiting

Serotonin Release in Premotor and Motor PD

Parkinson DiseasePositron Emission TomographyNeurodegenerative Diseases+3 more
University of Exeter42 enrolled1 locationNCT05516732
Recruiting

Longitudinal Investigation of I2BS in PD

Parkinson DiseasePositron Emission TomographyNeurodegenerative Diseases+3 more
University of Exeter44 enrolled1 locationNCT05516719
Recruiting
Not Applicable

Effects of Long Term Ventilation Support on the Quality of Life of ALS Patients and Their Families

Amyotrophic Lateral SclerosisNervous System DiseasesSpinal Cord Diseases+3 more
Haukeland University Hospital200 enrolled9 locationsNCT05744310