Nonalcoholic Fatty Liver Clinical Trials

26 recruitingLast updated: June 21, 2026

There are 26 actively recruiting nonalcoholic fatty liver clinical trials across 14 countries. Studies span Not Applicable, Phase 4, Phase 2. Top locations include Beijing, Beijing Municipality, China, Morgantown, West Virginia, United States, Oklahoma City, Oklahoma, United States. Updated daily from ClinicalTrials.gov.


Nonalcoholic Fatty Liver Trials at a Glance

26 actively recruiting trials for nonalcoholic fatty liver are listed on ClinicalTrialsFinder across 6 cities in 14 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Beijing, Morgantown, and Oklahoma City. Lead sponsors running nonalcoholic fatty liver studies include Beijing Tsinghua Chang Gung Hospital, Bettina Mittendorfer, and Aristotle University Of Thessaloniki.

Browse nonalcoholic fatty liver trials by phase

Treatments under study

About Nonalcoholic Fatty Liver Clinical Trials

Looking for clinical trials for Nonalcoholic Fatty Liver? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Nonalcoholic Fatty Liver trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Nonalcoholic Fatty Liver clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 26 trials

Recruiting

Screening and Follow-up in Patients With HIV Infection Combined With Metabolic Associated Fatty Liver Disease

FibrosisNonalcoholic SteatohepatitisNonalcoholic Fatty Liver Disease+1 more
Peking Union Medical College Hospital2,000 enrolled1 locationNCT05330923
Recruiting

Accurate Point of Care Liver Disease Diagnostics (Phase 2)

MASLDNAFLD (Nonalcoholic Fatty Liver Disease)NAFLD+1 more
University of California, San Diego26 enrolled1 locationNCT07518784
Recruiting

A Longitudinal Observational Study of Patients With Nonalcoholic Steatohepatitis (NASH) and Related Conditions Across the Entire Spectrum of Nonalcoholic Fatty Liver Disease (NAFLD)

Nonalcoholic SteatohepatitisNonalcoholic Fatty Liver
Target PharmaSolutions, Inc.15,000 enrolled74 locationsNCT02815891
Recruiting
Not Applicable

iWAIST Trial: ERCG (Endoscopic Radial Compression Gastroplasty) vs Optimized Lifestyle Intervention for Weight Loss

Metabolic SyndromeNonalcoholic Fatty Liver DiseaseOverweight and/or Obesity+1 more
Liu Yan216 enrolled2 locationsNCT07237750
Recruiting
Phase 4

Effect of a GnRH Analog on Hepatic Steatosis

EndometriosisMetabolic Dysfunction-Associated Steatotic Liver DiseaseNonalcoholic Fatty Liver
Aristotle University Of Thessaloniki62 enrolled2 locationsNCT06523530
Recruiting

Validating Integrative Multi-omics Approaches in Metabolic Syndrome-related Diseases

HealthyObesity, OverweightChronic Kidney Disease+3 more
Chang Gung Memorial Hospital6,266 enrolled1 locationNCT07248371
Recruiting

To Explore the Value of New MR Technology in Non-invasive Quantitative Assessment of Systemic Metabolism, Disease Status and Prognosis in Patients With Metabolic-Associated Fatty Liver Disease

Metabolic Associated Fatty Liver DiseaseNonalcoholic Fatty Liver Disease
Tongji Hospital500 enrolled1 locationNCT07149571
Recruiting
Not Applicable

The Impact of Pectin Supplementation on Systematic Inflammation Pathway, Gut Microbiome, and Metabolic Health in Patients With Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

MASLDNAFLD (Nonalcoholic Fatty Liver Disease)Metabolic Dysfunction-Associated Steatotic Liver Disease+5 more
University of Nottingham45 enrolled3 locationsNCT07093346
Recruiting
Not Applicable

Gepaktiv vs UDCA and Ademetionine in MAFLD With Hepatomegaly

Fatty Liver DiseaseHepatomegalyFatty Liver+5 more
Phenomen Pharma90 enrolled1 locationNCT07068191
Recruiting
Not Applicable

Harnessing Macrophage Lysosomal Lipid Metabolism in Obesity

ObesityHealthyDiabetes Type 2+1 more
Bettina Mittendorfer60 enrolled1 locationNCT06335771
Recruiting

Digital Early Warning System for Acute Lung Injury in Liver Surgery

MASLD/MASH (Metabolic Dysfunction-Associated Steatotic Liver Disease / Metabolic Dysfunction-Associated Steatohepatitis)Acute Lung Injury(ALI)Liver Cirrhosis+4 more
Beijing Tsinghua Chang Gung Hospital4,000 enrolled1 locationNCT07070362
Recruiting
Not Applicable

Digital Therapy for Fatty Liver Disease

Steatohepatitis, NonalcoholicNonalcoholic Fatty Liver
Xinhua Hospital, Shanghai Jiao Tong University School of Medicine120 enrolled1 locationNCT07007741
Recruiting
Phase 2

Phase 2a Study of Safety, Tolerability, and Efficacy of TLC-2716 in Subjects With Hypertriglyceridemia and NAFLD

Nonalcoholic Fatty Liver DiseaseHypertriglyceridemia
OrsoBio, Inc30 enrolled4 locationsNCT06564584
Recruiting

Follow-up of Chronic Hepatitis B Patients With Comorbid Nonalcoholic Fatty Liver Disease

Chronic Hepatitis BNonalcoholic Fatty Liver Disease
Humanity and Health Research Centre1,500 enrolled1 locationNCT02863757
Recruiting

Quantitative Ultrasound Techniques for Diagnosis of Nonalcoholic Steatohepatitis

Nonalcoholic Steatohepatitis (NASH)Nonalcoholic Fatty Liver Disease (NAFLD)
Centre hospitalier de l'Université de Montréal (CHUM)102 enrolled1 locationNCT03572465
Recruiting

Effectiveness of Endoscopic Sleeve Gastroplasty in Nonalcoholic Fatty Liver Disease/Nonalcoholic Steatohepatitis

Nonalcoholic Fatty Liver Disease
West Virginia University30 enrolled1 locationNCT05507151
Recruiting
Not Applicable

Longitudinal Multi-Omic Profiles to Reveal Mechanisms of Obesity-Mediated Insulin Resistance

ObesityInsulin ResistanceDiabetes Mellitus, Type 2+4 more
Stanford University110 enrolled1 locationNCT05165706
Recruiting
Not Applicable

Gastric Bypass Stent Small-Sample-Size Study For Nonalcoholic Fatty Liver Disease

Nonalcoholic Fatty Liver Disease
Hangzhou Tangji Medical Technology Co., Ltd.10 enrolled1 locationNCT05495139
Recruiting
Phase 4

Effect of Henagliflozein on Hepatic Fat Content in Patients With T2DM and NAFLD

Type2 Diabetes MellitusNonalcoholic Fatty Liver Disease
Zhujiang Hospital100 enrolled1 locationNCT06449833
Recruiting
Phase 4

Efficacy and Safety of Antiviral Therapy With Peg-interferon for Chronic Hepatitis B Complicated With Nonalcoholic Fatty Liver Disease(OCEAN PROJECT)

Chronic Hepatitis BNonalcoholic Fatty Liver Disease
First Affiliated Hospital of Wenzhou Medical University1,500 enrolled5 locationsNCT06368882