Phase 2 Obstructive Clinical Trials
73 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 73 trials
Recruiting
Phase 2Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer1,156 enrolled87 locationsNCT07363694
Recruiting
Phase 2
A Study to Assess the Safety, Tolerability, PK and PD of WIN378 in Participants With Moderate - Severe COPD
COPD, Chronic Obstructive Pulmonary Disease
Windward Bio105 enrolled3 locationsNCT07646587
Recruiting
Phase 2
Evaluation of the Safety and Efficacy of HSK39004 Dry Powder Inhaler and HSK39004 Inhalation Suspension in Chinese Patients With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Lung Disease (COLD)
Haisco Pharmaceutical Group Co., Ltd.50 enrolled1 locationNCT07140328
Recruiting
Phase 2
A Study to Evaluate the Efficacy and Safety of RSS0343 Tablets in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease
Reistone Biopharma Company Limited300 enrolled1 locationNCT07349524
Recruiting
Phase 2
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca987 enrolled366 locationsNCT07082738
Recruiting
Phase 2
Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD
Chronic Obstructive Pulmonary Disease
University of Alberta160 enrolled1 locationNCT05061368
Recruiting
Phase 2
The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)
Chronic Obstructive Pulmonary DiseaseObstructive Sleep ApneaOverlap Syndrome
University of California, San Diego240 enrolled1 locationNCT05237505
Recruiting
Phase 2
A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD
Chronic Obstructive Pulmonary Disease
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA480 enrolled57 locationsNCT07016412
Recruiting
Phase 2
Phototherapy for Non-responders to Oral Appliance Therapy for Obstructive Sleep Apnea
Obstructive Sleep Apnea
University of Alberta528 enrolled1 locationNCT06960200
Recruiting
Phase 2
Intravesical Aminophylline for Urgent Ureteral Stenting in Acute Calculous Anuria
Acute Kidney InjuryUreteral CalculiAcute Calculous Anuria+1 more
Beni-Suef University72 enrolled1 locationNCT07617948
Recruiting
Phase 2
A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy
Non-obstructive Hypertrophic Cardiomyopathy
Imbria Pharmaceuticals, Inc.165 enrolled67 locationsNCT07023614
Recruiting
Phase 2
Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH
Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854
Recruiting
Phase 2
Dexmedetomidine Versus Propofol Sedation for Drug-Induced Sleep Endoscopy in Pediatric Obstructive Sleep Apnea
Obstructive Sleep Apnea
Erin Kirkham90 enrolled1 locationNCT05303987
Recruiting
Phase 2
Patient-centered and Neurocognitive Outcomes With Acetazolamide for Sleep Apnea
Obstructive Sleep Apnea
University of California, San Diego60 enrolled1 locationNCT05804084
Recruiting
Phase 2
EFFECT OF A SUBSTANCE P ANTAGONIST ON THE SECRETION OF ALDOSTERONE IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA SYNDROME AND ARTERIAL HYPERTENSION
Apnea, Obstructive
University Hospital, Rouen24 enrolled1 locationNCT06462287
Recruiting
Phase 2
Psilocybin Therapy for Psychological Distress in Palliative Patients
COPD, Chronic Obstructive Pulmonary DiseaseMajor Depressive Disorder (MDD)ALS (Amyotrophic Lateral Sclerosis)+2 more
University Medical Center Groningen108 enrolled4 locationsNCT06782724
Recruiting
Phase 1Phase 2
Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia
Hypoxia, BrainBlood PressureStroke+5 more
University of Calgary12 enrolled1 locationNCT03255408
Recruiting
Phase 1Phase 2
Feasibility of Semaglutide in Advanced Lung Disease
ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 1Phase 2
Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa
Chronic Obstructive Pulmonary Disease
University Hospital, Grenoble24 enrolled1 locationNCT04427826
Recruiting
Phase 2
Phase II Study of RC1416 Injection in COPD
Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Nanjing RegeneCore Biotech Co., Ltd.180 enrolled41 locationsNCT07402551