Phase 3 Oral Clinical Trials
24 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 24 trials
Recruiting
Phase 2Phase 3
Testing Docetaxel-Cetuximab or the Addition of an Immunotherapy Drug, Atezolizumab, to the Usual Chemotherapy and Radiation Therapy in High-Risk Head and Neck Cancer
Oropharyngeal p16INK4a-Negative Squamous Cell CarcinomaStage III Hypopharyngeal Squamous Cell Carcinoma AJCC v7Stage III Laryngeal Squamous Cell Carcinoma AJCC v6 and v7+6 more
National Cancer Institute (NCI)613 enrolled341 locationsNCT01810913
Recruiting
Phase 3
Testing the Addition of Anti-Cancer Drug, Cetuximab, to Standard of Care Treatment (Pembrolizumab) for Returning or Spreading Head and Neck Cancer After Previous Treatment
Metastatic Head and Neck Squamous Cell CarcinomaStage IV Head and Neck Cutaneous Squamous Cell Carcinoma AJCC v8Recurrent Head and Neck Squamous Cell Carcinoma+18 more
National Cancer Institute (NCI)158 enrolled176 locationsNCT06589804
Recruiting
Phase 2Phase 3
A Study Evaluating the Safety and Efficacy of PRV111, PRV211, and PRV131 in Subjects With Oral and Lung Cancers
Oral Squamous Cell Carcinoma
Privo Technologies40 enrolled4 locationsNCT05893888
Recruiting
Phase 2Phase 3
Comparing Sentinel Lymph Node (SLN) Biopsy With Standard Neck Dissection for Patients With Early-Stage Oral Cavity Cancer
Tongue Squamous Cell CarcinomaOral Cavity Squamous Cell CarcinomaStage I Lip and Oral Cavity Cancer AJCC v8+9 more
NRG Oncology686 enrolled106 locationsNCT04333537
Recruiting
Phase 3
Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (EPIC (EPIlepsy Cell Therapy))
Mesial Temporal Lobe Epilepsy
Neurona Therapeutics88 enrolled33 locationsNCT05135091
Recruiting
Phase 2Phase 3
De-Intensification of Postoperative Radiotherapy in Patients With Squamous Cell Carcinoma of the Head and Neck
Squamous Cell Carcinoma of the LarynxSquamous Cell Carcinoma of the OropharynxSquamous Cell Carcinoma of the Oral Cavity+1 more
University of Erlangen-Nürnberg Medical School508 enrolled1 locationNCT06030440
Recruiting
Phase 3
Flap Sparing in Postoperative Radiotherapy of Oral Cavity Cancers
Radiotherapy, AdjuvantOral Cavity CarcinomaFlap+1 more
Centre Francois Baclesse348 enrolled25 locationsNCT06798922
Recruiting
Phase 2Phase 3
Treatment Outcomes and Patient Satisfaction of Oral Lichen Planus Treatment
Erosive Oral Lichen PlanusAtrophic Lichen Planus
Dar Al Uloom University56 enrolled1 locationNCT06988527
Recruiting
Phase 3
Low-level Laser Therapy in the Prevention of Chemotherapy-induced Mucositis in Children and Young Adults
Mucositis Oral
Gustave Roussy, Cancer Campus, Grand Paris315 enrolled5 locationsNCT03983369
Recruiting
Phase 3
Sintilimab Plus Chemotherapy as Neoadjuvant and Adjuvant Treatment for Locally Advanced Oral Squamous Cell Carcinoma
Oral Squamous Cell Carcinoma (OSCC)Locally Advanced Oral Squamous Cell Carcinoma
Qunxing Li,MD104 enrolled1 locationNCT07371611
Recruiting
Phase 3
Prevention and Treatment of Radiation-Induced Oral Mucositis in NPC With Houyanqing Oral Liquid
Nasopharyngeal Cancinoma (NPC)Radiation-induced Oral Mucositis
Sun Yat-sen University244 enrolled16 locationsNCT07311772
Recruiting
Phase 3
PET Imaging Tau Accumulation in FTLD and Atypical Alzheimer's Using [18F]-PI-2620
Alzheimer DiseaseFrontotemporal Lobar DegenerationCognitively Normal
University of Pennsylvania72 enrolled1 locationNCT05456503
Recruiting
Phase 2Phase 3
Food-Body-Mind Intervention (16 Weeks)
Obesity, ChildhoodMental Health WellnessSocial Skills+2 more
Michigan State University800 enrolled1 locationNCT06597474
Recruiting
Phase 2Phase 3
Mandibular Reconstruction Preplanning (ViPMR)
Oral CancerOral Cavity Cancer
University of British Columbia420 enrolled1 locationNCT05429099
Recruiting
Phase 3
Art-Based Pain Assessment Tool in Patients With Temporomandibular Joint Disorders
Temporomandibular Disorders (TMD)Wilkes 1 and 2TMJ Pain+3 more
King Abdulaziz University70 enrolled1 locationNCT07018791
Recruiting
Phase 3
Neoadjuvant Immunochemotherapy for LAOSCC
Oral Squamous Cell CarcinomaLocally Advanced Head and Neck Carcinoma
Lai-ping Zhong134 enrolled1 locationNCT06258811
Recruiting
Phase 3
Upfront Surgery Vs Induction Chemotherapy Followed By Surgery In Oral Cancers:
Head and Neck NeoplasmsOral Cancer
All India Institute of Medical Sciences, Jodhpur346 enrolled7 locationsNCT06737822
Recruiting
Phase 3
Comparing the Outcome of Electrical Stimulation and Physical Therapy in Patellofemoral Pain Syndrome
Patellofemoral Pain Syndrome
Northwell Health92 enrolled1 locationNCT03184545
Recruiting
Phase 3
Neoadjuvant Anti-PD-1 Immunotherapy With Chemotherapy in Resectable Locally Advanced Oral Squamous Cell Carcinoma
Oral Squamous Cell Carcinoma
Hospital of Stomatology, Wuhan University309 enrolled3 locationsNCT05798793
Recruiting
Phase 2Phase 3
Neoadjuvant Anti-PD-1 and TP Versus TPF on Pathological Response in OSCC
ChemotherapyOral Squamous Cell CarcinomaNeoadjvant Therapy+1 more
Shanghai Jiao Tong University School of Medicine80 enrolled1 locationNCT05125055