Phase 3 Osteoarthritis Clinical Trials
50 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 50 trials
Recruiting
Phase 3
A Study of Orforglipron (LY3502970) in Participants With Obesity or Overweight and Osteoarthritis (OA) of the Knee
Osteoarthritis
Eli Lilly and Company800 enrolled95 locationsNCT07153471
Recruiting
Phase 3
Efficacy and Safety of Eloralintide (LY3841136) in Participants With Osteoarthritis Knee Pain and Obesity or Overweight
OsteoarthritisOverweight or Obesity
Eli Lilly and Company900 enrolled160 locationsNCT07353931
Recruiting
Phase 3
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
ObesityKnee osteoarthritis (OA)
Novo Nordisk A/S400 enrolled82 locationsNCT07481630
Recruiting
Phase 3
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
ObesityOverweightOsteoarthritis, Knee
Novo Nordisk A/S400 enrolled81 locationsNCT07509307
Recruiting
Phase 3
Phase III Study to Assess the Safety and Efficacy of SL1002 for Osteoarthritis Knee Pain
Osteoarthritis Knee Pain
Saol Therapeutics Inc150 enrolled20 locationsNCT07226258
Recruiting
Phase 3
A Study to Investigate the Treatment Effect of Subcutaneous Injections of Pentosan Polysulfate Sodium Compared With Placebo in Adult Participants With Knee Osteoarthritis Pain.
Osteoarthritis, Knee
Paradigm Biopharmaceuticals Ltd.466 enrolled56 locationsNCT06917404
Recruiting
Phase 3
Multiprofen-CC to Reduce Pain in Hand Arthritis
Hand Osteoarthritis
St. Joseph's Healthcare Hamilton42 enrolled1 locationNCT06966206
Recruiting
Phase 3
A Study to Evaluate the Efficacy and Safey of PTP-001 (MOTYS™) in Knee Osteoarthritis Patients
Knee Osteoarthritis
Doron Therapeutics Inc.260 enrolled17 locationsNCT07219771
Recruiting
Phase 2Phase 3
An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis
Knee Arthritis, Osteoarthritis
Cellcolabs Clinical SPV Limited140 enrolled1 locationNCT07542808
Recruiting
Phase 2Phase 3
Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.
OsteoarthritisBase-of-thumb Osteoarthritis
Assistance Publique - Hôpitaux de Paris120 enrolled1 locationNCT06902805
Recruiting
Phase 3
NSAID Injection Versus Corticosteroid Injection for Basilar Thumb Arthritis
Thumb Osteoarthritis
Mayo Clinic240 enrolled1 locationNCT05992883
Recruiting
Phase 3
PRP in ACLR to Prevent PTOA
Post-traumatic OsteoarthritisAnterior Cruciate Ligament InjuriesPRP
Hospital for Special Surgery, New York56 enrolled1 locationNCT05412381
Recruiting
Phase 3
Probiotic Supplements in Osteoarthritis
Osteoarthritis, Knee
Beni-Suef University146 enrolled1 locationNCT07364578
Recruiting
Phase 3
The Beat Pain Better Trial
OsteoarthritisChronic Pain Management
University of Utah346 enrolled3 locationsNCT06932887
Recruiting
Phase 3
Amniotic Suspension Allograft Injection for Knee Osteoarthritis
OsteoarthritisKnee
Chang Gung Memorial Hospital160 enrolled2 locationsNCT06704893
Recruiting
Phase 3
The Efficacy and Safety of Intramuscular Methylprednisolone in Patients With Hand OsteoArthritis
Hand Osteoarthritis
Sint Maartenskliniek212 enrolled1 locationNCT07371572
Recruiting
Phase 3
Rehabilitation for Arthritis of The Knee: mainTaining Improvement for Veterans
Osteoarthritis, Knee
VA Office of Research and Development254 enrolled5 locationsNCT06488144
Recruiting
Phase 2Phase 3
Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA
Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 3
A Phase III Study of CLS2901C in Patients With Osteoarthritis of the Knee
Osteoarthritis of the knee
CellSeed Inc.96 enrolled6 locationsNCT06549686
Recruiting
Phase 3
ZILRETTA in Subjects With Shoulder Osteoarthritis
Glenohumeral Osteoarthritis
Pacira Pharmaceuticals, Inc150 enrolled32 locationsNCT06269705