Phase 2 Osteoarthritis Clinical Trials

73 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 73 trials

Recruiting
Phase 2

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

Osteoarthritis, Knee
Eli Lilly and Company10,000 enrolled64 locationsNCT05986292
Recruiting
Phase 2

Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 1Phase 2

CBD for Pain Following Orthopedic Shoulder Surgery

Shoulder Osteoarthritis
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting
Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 2

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 2Phase 3

Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.

OsteoarthritisBase-of-thumb Osteoarthritis
Assistance Publique - Hôpitaux de Paris120 enrolled1 locationNCT06902805
Recruiting
Phase 2

Platelet Rich Plasma Injections In Young And Old Human Subjects

OsteoarthritisMusculoskeletal DisordersArticular Cartilage
University of California, San Francisco60 enrolled1 locationNCT06451120
Recruiting
Phase 1Phase 2

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Knee Osteoarthritis (Knee OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 2

A Mobile Intervention to Reduce Pain and Improve Health-III

Obesity and OverweightChronic PainOsteoarthritis+1 more
Wake Forest University200 enrolled1 locationNCT06623669
Recruiting
Phase 2

Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)

Trapeziometacarpal Osteoarthritis
Université du Québec à Trois-Rivières40 enrolled2 locationsNCT06401317
Recruiting
Phase 2Phase 3

Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA

Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 2

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Chronic PainOsteoarthritis, Knee
Wake Forest University Health Sciences38 enrolled1 locationNCT04427709
Recruiting
Phase 2

The Safety/Efficacy of hUC Mesenchymal Stem Cells(19#iSCLife®-OA) Therapy for Patients With Osteoarthritis

Osteoarthritis, Knee
Sclnow Biotechnology Co., Ltd.60 enrolled1 locationNCT03383081
Recruiting
Phase 2

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Shoulder

Osteoarthritis
VivaTech International, Inc.4,000 enrolled1 locationNCT02844738
Recruiting
Phase 2

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Knee

Osteoarthritis
VivaTech International, Inc.4,000 enrolled1 locationNCT02844751
Recruiting
Phase 2

Safety & Effectiveness of Autologous Regenerative Cell Therapy on Pain & Inflammation of Osteoarthritis of the Hip

Osteoarthritis
VivaTech International, Inc.4,000 enrolled1 locationNCT02844764
Recruiting
Phase 2

Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of STT Osteoarthritis

Osteoarthritis Hand
TBF Genie Tissulaire14 enrolled4 locationsNCT06038331
Recruiting
Phase 2

Use of a Treated, Devitalized and Sterile Umbilical Cord Amniotic Membrane in the Treatment of PIP Joint Osteoarthritis

Osteoarthritis Hand
TBF Genie Tissulaire14 enrolled3 locationsNCT06034262
Recruiting
Phase 2

An Study to Evaluate Safety and Tolerability of OA-SYS in Subjects With Moderate to Severe Osteoarthritis of the Knee Joint

Osteo Arthritis KneeOsteoarthritis
Ageless Biotech, Inc.400 enrolled1 locationNCT06485843
Recruiting
Phase 1Phase 2

CBD for Knee Osteoarthritis

Osteoarthritis, Knee
University of Florida30 enrolled1 locationNCT06414473