Phase 2 Osteoarthritis Clinical Trials

79 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 79 trials

Recruiting
Phase 2

Intra-Articular Allocetra in Patients With Primary Knee Osteoarthritis

Primary Knee Osteoarthritis
Enlivex Therapeutics Ltd.270 enrolled17 locationsNCT07580716
Recruiting
Phase 2

Treatment of Patellofemoral Osteoarthritis With Engineered Cartilage.

Patellofemoral osteoarthritis
University Hospital, Basel, Switzerland75 enrolled9 locationsNCT06163573
Recruiting
Phase 2

Pain Relief After Trapeziectomy: Ibuprofen & Acetaminophen Versus Oxycodone

Pain, PostoperativeOsteoarthritis Thumb
Stanford University121 enrolled2 locationsNCT04676802
Recruiting
Phase 1Phase 2

Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment

Osteoarthritis
University Hospital, Grenoble15 enrolled1 locationNCT06611007
Recruiting
Phase 1Phase 2

COntralateral CorticoSTeroid Injection in Total Knee Arthroplasty

Total Knee AnthroplastyOsteoarthritis PrimaryBilateral Knee Osteoarthritis+1 more
Unity Health Toronto60 enrolled1 locationNCT06809998
Recruiting
Phase 2

A Master Protocol Study (LY900028) of Multiple Intervention-Specific-Appendices (ISAs) in Participants With Chronic Pain

diabetic neuropathic painChronic Low-back PainOsteoarthritis, Knee
Eli Lilly and Company10,000 enrolled64 locationsNCT05986292
Recruiting
Phase 2

Phase II Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis

Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology100 enrolled3 locationsNCT07547735
Recruiting
Phase 2Phase 3

An Open-Label, Double-Treatment Group Study to Evaluate the Efficacy and Safety of Human Allogeneic Bone-Marrow- Derived Mesenchymal Stromal Cell Product StromaForte Compared With Hyaluronic Acid for the Treatment of Knee Osteoarthritis

Knee Arthritis, Osteoarthritis
Cellcolabs Clinical SPV Limited140 enrolled1 locationNCT07542808
Recruiting
Phase 1Phase 2

CBD for Pain Following Orthopedic Shoulder Surgery

Shoulder Osteoarthritisrotator cuff injuries
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting
Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 2

A Trial to Investigate the Safety and Efficacy of Intra-articular 4P004 Injection in Subjects With Knee Synovitis and Osteoarthritis

Knee OsteoarthritisSynovitis of Knee
4Moving Biotech129 enrolled22 locationsNCT07225829
Recruiting
Phase 2Phase 3

Efficacy of Two Ultrasound-guided Intra-articular Injections of Botox® Combined With Custom-made Rigid Splinting in Painful Base-of-thumb Osteoarthritis.

OsteoarthritisBase-of-thumb Osteoarthritis
Assistance Publique - Hôpitaux de Paris120 enrolled1 locationNCT06902805
Recruiting
Phase 2

Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.

Patellofemoral osteoarthritis
University Hospital, Basel, Switzerland150 enrolled11 locationsNCT06576583
Recruiting
Phase 2

Platelet Rich Plasma Injections In Young And Old Human Subjects

OsteoarthritisMusculoskeletal DisordersArticular Cartilage
University of California, San Francisco60 enrolled1 locationNCT06451120
Recruiting
Phase 1Phase 2

Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)

Knee Osteoarthritis (Knee OA)Knee osteoarthritis (OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 2

A Mobile Intervention to Reduce Pain and Improve Health-III

Obesity and OverweightChronic PainOsteoarthritis+1 more
Wake Forest University200 enrolled1 locationNCT06623669
Recruiting
Phase 2

Corticosteroid Against Saline Injections for Thumb Osteoarthritis (CASITOA)

Trapeziometacarpal Osteoarthritis
Université du Québec à Trois-Rivières40 enrolled2 locationsNCT06401317
Recruiting
Phase 2Phase 3

Autologous BMA vs Saline and LAM + LP-PRP vs Saline Evaluations in Knee OA

Osteoarthritis, Knee
University Health Network, Toronto148 enrolled2 locationsNCT05517434
Recruiting
Phase 2

Generate and Test the Reliability of a PD Model of OXT on Pupillary Hippus as a Measure of CNS Activity

Chronic PainOsteoarthritis, Knee
Wake Forest University Health Sciences38 enrolled1 locationNCT04427709
Recruiting
Phase 2

The Safety/Efficacy of hUC Mesenchymal Stem Cells(19#iSCLife®-OA) Therapy for Patients With Osteoarthritis

Osteoarthritis, Knee
Sclnow Biotechnology Co., Ltd.60 enrolled1 locationNCT03383081