Phase 1 Osteoarthritis Clinical Trials
33 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 33 trials
Recruiting
Phase 1Phase 2
CBD for Pain Following Orthopedic Shoulder Surgery
Shoulder Osteoarthritis
The Methodist Hospital Research Institute80 enrolled1 locationNCT06381791
Recruiting
Phase 1
A Phase Ib Study to Evaluate the Efficacy and Safety of HRS-2129 in Patients With Knee Osteoarthritis
Moderate Pain in Knee OsteoarthritisSevere Pain in Knee Osteoarthritis
Shandong Suncadia Medicine Co., Ltd.200 enrolled1 locationNCT07351968
Recruiting
Phase 1Phase 2
Recombinant Human Growth Hormone (rHGH) for Knee Osteoarthritis (KORR)
Knee Osteoarthritis (Knee OA)
Dr. David Wasserstein34 enrolled1 locationNCT07036003
Recruiting
Phase 1
A Clinical Study to Evaluate the Safety, Tolerability and Efficacy of BBM-A101 in the Treatment of Knee Osteoarthritis.
Knee Osteoarthritis
Belief BioMed (Beijing) Co., Ltd81 enrolled2 locationsNCT07198555
Recruiting
Phase 1
The Effect of Micro Fragmented Adipose Tissue (MFAT) on Shoulder Osteoarthritis
Shoulder PainOsteoarthritis Shoulder
Stanford University48 enrolled1 locationNCT04929951
Recruiting
Phase 1
FiH Safety and Feasibility Study Assessing Intra-articular Administration of aeGF in Patients With Knee Osteoarthritis
Osteoarthritis, Knee
Scarcell Therapeutics S.A.S.15 enrolled1 locationNCT06690710
Recruiting
Phase 1Phase 2
CBD for Knee Osteoarthritis
Osteoarthritis, Knee
University of Florida30 enrolled1 locationNCT06414473
Recruiting
Phase 1
Oral Steroid Taper After Total Knee Arthroplasty
Osteoarthritis, Knee
Columbia University130 enrolled1 locationNCT07070882
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for OA
OsteoarthritisSpinal Arthritis
The Foundation for Orthopaedics and Regenerative Medicine92 enrolled2 locationsNCT05147675
Recruiting
Phase 1
Sustained Acoustic Medicine for Osteoarthritis Pain
Osteoarthritis
ZetrOZ, Inc.200 enrolled1 locationNCT05254574
Recruiting
Phase 1Phase 2
Evaluation of the Safety of LipiodolⓇ Embolization in Symptomatic Digital Osteoarthritis Refractory to Conventional Treatment
Osteoarthritis
University Hospital, Grenoble15 enrolled1 locationNCT06611007
Recruiting
Phase 1
Intra-articular Allocetra in Osteoarthritis of the of the Temporomandibular Joint (TMJ)
Temporomandibular Joint Osteoarthritis
Dr. Amit Druyan6 enrolled1 locationNCT06748651
Recruiting
Phase 1
Optimal Anesthetic for Corticosteroid Injections for Knee Osteoarthritis
Knee Osteoarthritis
Foundation for Orthopaedic Research and Education75 enrolled1 locationNCT05906433
Recruiting
Phase 1
Phase I Clinical Trial of UC-MSCs in the Treatment of Knee Osteoarthritis
Knee Osteoarthritis
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology18 enrolled1 locationNCT06463847
Recruiting
Phase 1Phase 2
Intra-articular Allocetra in Osteoarthritis of the 1st Carpo-metacarpal Joint
Osteoarthritis Thumb
Kaplan Medical Center46 enrolled1 locationNCT06459063
Recruiting
Phase 1Phase 2
Allogenic Mesenchymal Stem Cell Intraarticular Injection for Knee Osteoarthritis Therapy
Knee Osteoarthritis
Aarhus University Hospital80 enrolled1 locationNCT05933434
Recruiting
Phase 1
Six-month Performance of Meniscal Wall Infiltration Under Ultrasound to Treat Stable Degenerative Meniscal Injuries.
Osteoarthritis, Knee
Centre Hospitalier Universitaire de Nīmes70 enrolled1 locationNCT05235854
Recruiting
Phase 1
Bioequivalence Assessment of Topical Smartech 2% Diclofenac Sodium Solution Compared to a Reference Product When Applied to the Knees of Healthy Male and Female Participants
Osteoarthritis of the knee
Smartech Topical AU Pty Ltd90 enrolled1 locationACTRN12624000341527
Completed
Phase 1
A Phase I, Open-Label Study to Evaluate the Safety and Pharmacokinetics of APC201 in Healthy Volunteers
AnaesthesiologyPain associated with osteoarthritis of the knee
Andros Pharmaceuticals Pty Ltd10 enrolled1 locationACTRN12623000261617
Completed
Phase 1
Comparative Bioavailability of Smartech 2% Sodium Diclofenac Topical Solution and PENNSAID 2% Applied to the Knees of Healthy Male and Female Subjects
Osteoarthritis
Avance Clinical Pty Ltd32 enrolled1 locationACTRN12622001391763