Overweight and/or Obesity Clinical Trials

12 recruitingLast updated: June 18, 2026

There are 12 actively recruiting overweight and/or obesity clinical trials across 15 countries. Studies span Not Applicable, Phase 1, Phase 2, Phase 3. Top locations include Los Alamitos, California, United States, Lutherville, Maryland, United States, Beijing, Beijing Municipality, China. Updated daily from ClinicalTrials.gov.


Overweight and/or Obesity Trials at a Glance

12 actively recruiting trials for overweight and/or obesity are listed on ClinicalTrialsFinder across 6 cities in 15 countries. The largest study group is Not Applicable with 7 trials, with the heaviest enrollment activity in Los Alamitos, Lutherville, and Beijing. Lead sponsors running overweight and/or obesity studies include Pfizer, Hangzhou Sciwind Biosciences Co., Ltd., and George Mason University.

Browse overweight and/or obesity trials by phase

Treatments under study

About Overweight and/or Obesity Clinical Trials

Looking for clinical trials for Overweight and/or Obesity? There are currently 12 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Overweight and/or Obesity trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Overweight and/or Obesity clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Not Applicable

Brief Inhibitory Training for Eating - Intervention

Overweight and/or Obesity
George Mason University36 enrolled1 locationNCT07592728
Recruiting
Phase 2

A Study of PF-08653945 and PF-08653944 in Adults With Overweight or Obesity (SOLIS-1)

ObesityBody WeightOverweight+5 more
Pfizer872 enrolled48 locationsNCT07575932
Recruiting
Phase 3

A Study to Learn About the Study Medicine (PF-08653944) in People With Obesity or Overweight and Type 2 Diabetes (T2D)

ObesityOverweightType 2 Diabetes+2 more
Pfizer999 enrolled183 locationsNCT07400653
Recruiting
Not Applicable

Effects of Whole-Body High-Intensity Interval Training on Fitness in Overweight Adults

Overweight and/or Obesity
Université Libre de Bruxelles40 enrolled1 locationNCT07582718
Recruiting
Phase 1

A Study to Learn About the Effect of Study Medicine Called PF-08653944 on How Quickly the Stomach Empties Its Content in Healthy Adults With Overweight or Obesity

ObesityOverweightDrug Interaction+1 more
Pfizer20 enrolled1 locationNCT07508241
Recruiting
Not Applicable

Piloting a Generative Artificial Intelligence Chatbot in a Mobile Weight Loss Program

Overweight and/or Obesity
University of North Carolina, Chapel Hill20 enrolled1 locationNCT07534254
Recruiting
Not Applicable

Effects of a 6-months Fiber- and Polyphenol-rich Diet on Brain Inflammatory Processes in Perimenopausal Women Living With Overweight or Obesity

Perimenopausal WomenOverweight and/or Obesity
Max Planck Institute for Human Cognitive and Brain Sciences120 enrolled1 locationNCT07501377
Recruiting
Not Applicable

Family-Based Nutrition Intervention to Prevent Overweight and Obesity in School-Age Children.

Overweight and/or ObesityChildren - MalnutritionPreventing Malnutrition
Claudia Teresa Tovar Palacio40 enrolled1 locationNCT07159971
Recruiting
Not Applicable

iWAIST Trial: ERCG (Endoscopic Radial Compression Gastroplasty) vs Optimized Lifestyle Intervention for Weight Loss

Metabolic SyndromeNonalcoholic Fatty Liver DiseaseOverweight and/or Obesity+1 more
Liu Yan216 enrolled2 locationsNCT07237750
Recruiting
Phase 1Phase 2

A Phase Ib/IIa Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Oral Ecnoglutide Tablets in Chinese Participants With Overweight or Obesity

Weight ManagementOverweight and/or Obesity
Hangzhou Sciwind Biosciences Co., Ltd.84 enrolled1 locationNCT07243171
Recruiting
Not Applicable

Norwegian Mental Illness Heart Health Study

Severe Mental DisorderMetabolic Syndrome (MetS)Severe Mental Illness+5 more
Madeleine Elisabeth Angelsen70 enrolled1 locationNCT07085923
Recruiting
Phase 3

DOR/TDF/3TC COmpared With BIC/FTC/TAF in ART-Naïve People Living With HIV and Overweight or Obesity

ObesityHIV (Human Immunodeficiency Virus)Overweight and/or Obesity
José Antonio Mata Marín306 enrolled1 locationNCT07075146