Phase 1 Pancreas Cancer Clinical Trials
27 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–20 of 27 trials
Recruiting
Phase 1Phase 2
Study of EGFRBi Armed Fresh PBMC in Metastatic or Unresectable Pancreatic Cancer
Pancreatic CancerPancreas Cancer
University of Virginia23 enrolled1 locationNCT06479239
Recruiting
Phase 1Phase 2
A Study to Evaluate the Safety and Efficacy of Mesothelin-Targeting Logic-gated CAR T, in Participants With Solid Tumors That Express MSLN and Have Lost HLA-A*02 Expression
Colorectal, CancerOvarian CancerLung Cancer+17 more
A2 Biotherapeutics Inc.474 enrolled12 locationsNCT06051695
Recruiting
Phase 1
Autologous CAR-T Cells Targeting B7-H3 in PDAC
Pancreas CancerRelapseResistant Cancer
UNC Lineberger Comprehensive Cancer Center27 enrolled1 locationNCT06158139
Recruiting
Phase 1Phase 2
A Phase 1 Study to Evaluate Safety and Efficacy of XER-001 (Amifostine for Nasoduodenal Delivery) in Combination With Sterotactic Body Radiotherapy for Treatment in Patients With Locally Advanced Pancreatic Cancer.
Locally Advanced Pancreatic AdenocarcinomaLocally Advanced Pancreas CancerLocally Advanced Pancreatic Ductal Adenocarcinoma
Xerient Pharma36 enrolled4 locationsNCT07157033
Recruiting
Phase 1
Safety, PK and Efficacy of QXL138AM in Patients With Solid Tumors and Multiple Myeloma
Breast CancerOvarian CancerProstate Cancer+6 more
Nammi Therapeutics Inc100 enrolled10 locationsNCT06582017
Recruiting
Phase 1Phase 2
Early Phase Study of KESONOTIDE™in Participants With Solid Tumours
Breast CancerLung CancersOvarian Cancer+4 more
Filamon LTD80 enrolled3 locationsNCT06926075
Recruiting
Phase 1Phase 2
Carbon Nanoparticle-Loaded Iron in the Treatment of Advanced Solid Tumor
Colorectal, CancerCervical CancerLung Cancer+4 more
Sichuan Enray Pharmaceutical Sciences Company54 enrolled9 locationsNCT07433283
Recruiting
Phase 1Phase 2
Nab-Paclitaxel + Cisplatin + Gemcitabine + TTF in pt. w/ Metastatic PAC
Metastatic Pancreatic CancerPancreas CancerPancreatic Adenocarcinoma+1 more
Mayo Clinic40 enrolled1 locationNCT04605913
Recruiting
Phase 1Phase 2
Phase 1/2 Dose Finding, Safety and PK Study in Advanced Refractory Solid Tumors
Breast CancerProstate Cancer Castration-resistant Prostate CancerColo-rectal Cancer+2 more
MBrace Therapeutics150 enrolled7 locationsNCT07145255
Recruiting
Phase 1
A Study of MGC026 in Participants With Advanced Solid Tumors
Breast CancerColorectal, CancerGastric Cancer+19 more
MacroGenics250 enrolled12 locationsNCT06242470
Recruiting
Phase 1
SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells
Breast Cancer MetastaticHER2-Negative Breast CarcinomaPancreatic Cancer+17 more
General Oncology, Inc.24 enrolled2 locationsNCT04150042
Recruiting
Phase 1
Study of Orally Administered MOMA-313 in Participants With Advanced or Metastatic Solid Tumors
Breast CancerOvarian CancerProstate Cancer+4 more
MOMA Therapeutics220 enrolled18 locationsNCT06545942
Recruiting
Phase 1
Chemotherapy and Irreversible Electroporation in the Treatment of Advanced Pancreatic Adenocarcinoma
Pancreas Cancer
University of Louisville20 enrolled1 locationNCT03484299
Recruiting
Phase 1
CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors
Esophageal CancerGastric CancerLung Cancer+3 more
Chongqing Precision Biotech Co., Ltd108 enrolled1 locationNCT07179692
Recruiting
Phase 1
Saleh's Technique for Pancreaticojejunostomy (Pancreatic Parenchymal Injection of N-butyl-2-cyanoacrylate)
Pancreas CancerPeriampullary CancerPancreaticoduodenectomy+1 more
Minia University30 enrolled1 locationNCT07132541
Recruiting
Phase 1
Study of Safety and Tolerability of BCA101 Monotherapy and in Combination Therapy in Patients With EGFR-driven Advanced Solid Tumors
Colorectal, CancerSquamous Cell Carcinoma of Head and NeckHead and Neck Squamous Cell Carcinoma+8 more
Bicara Therapeutics292 enrolled20 locationsNCT04429542
Recruiting
Phase 1Phase 2
Clinical Safty and Efficacy Study of Infusion of iNKT Cells and CD8+T Cells in Patients With Advanced Solid Tumor
Gastric CancerHepatocellular CarcinomaNon-small Cell Lung Cancer+3 more
Shanghai Public Health Clinical Center40 enrolled1 locationNCT03093688
Recruiting
Phase 1
A Phase I Study of LXP1788 Injection with Advanced Solid Tumors.
Pancreas CancerSolid Tumor CancerHCC - Hepatocellular Carcinoma+6 more
LaunXP Biomedical Co., Ltd.24 enrolled2 locationsNCT06883539
Recruiting
Phase 1Phase 2
Bortezomib Combined with PD-1 MAb and MFOLFIRINOX for Metastatic Pancreatic Cancer
Pancreas Cancer
Zhejiang University63 enrolled1 locationNCT06572813
Recruiting
Phase 1Phase 2
Surufatinib Plus Camrelizumab and AS in First Line Treatment of Advanced Metastatic Pancreatic Cancer
Pancreatic CancerPancreas CancerPancreatic Neoplasms+1 more
Chinese PLA General Hospital90 enrolled1 locationNCT05218889