Phase 3 Pediatric Clinical Trials
22 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 22 trials
Recruiting
Phase 3
Methylphenidate in Pediatric Brain Tumor Survivors With Cancer-related Fatigue
Cancer-related FatigueBrain Tumor, PediatricMethylphenidate
Odense University Hospital50 enrolled4 locationsNCT06905587
Recruiting
Phase 3
A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction
Left Ventricular Systolic DysfunctionHeart Failure (Pediatric)
Bayer111 enrolled133 locationsNCT07188805
Recruiting
Phase 3
Randomized Study in Children and Adolescents With Migraine: Acute Treatment
Pediatric Migraine
Pfizer2,100 enrolled246 locationsNCT04649242
Recruiting
Phase 2Phase 3
A Study to Evaluate the Effect of Aficamten in Pediatric Patients With Symptomatic Obstructive Hypertrophic Cardiomyopathy (oHCM).
PediatricSymptomatic Obstructive Hypertrophic Cardiomyopathy
Cytokinetics55 enrolled38 locationsNCT06412666
Recruiting
Phase 2Phase 3
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Phase 3
DAY101 vs. Standard of Care Chemotherapy in Pediatric Participants With Low-Grade Glioma Requiring First-Line Systemic Therapy (LOGGIC/FIREFLY-2)
Low-grade GliomaRapidly Accelerated Fibrosarcoma (RAF) Altered GliomaPediatric Low-grade Glioma
Day One Biopharmaceuticals, Inc.400 enrolled138 locationsNCT05566795
Recruiting
Phase 3
Optimizing Pain Treatment in Children On Mechanical Ventilation
Mechanical VentilationSedation and AnalgesiaAnalgesics, Opioid+1 more
Weill Medical College of Cornell University644 enrolled15 locationsNCT06994442
Recruiting
Phase 2Phase 3
A Trial of Remimazolam for Intraoperative Sedation in Pediatric and Adolescent Patients
Operative Sedation of PediatricOperative Sedation of Adolescent Patients
Jiangsu HengRui Medicine Co., Ltd.240 enrolled1 locationNCT07036419
Recruiting
Phase 3
Evaluation of Analgesia for Cardiac Elective Surgery in Children
Pediatric Cardiac Surgery
Senthil Sadhasivam500 enrolled1 locationNCT06626035
Recruiting
Phase 3
Advancing Brain Outcomes in Pediatric Critically Ill Patients Sedated With Volatile AnEsthestic Agents
Intensive Care Units, PediatricAnesthetics, InhalationMechanically Ventilated, Critically Ill Children
Sunnybrook Health Sciences Centre60 enrolled3 locationsNCT05867472
Recruiting
Phase 2Phase 3
Azithromycin for Critical Asthma - Pediatrics
Critical IllnessPediatric Asthma
Johns Hopkins All Children's Hospital100 enrolled1 locationNCT06223828
Recruiting
Phase 3
Pain Control Alternatives in Pediatric Patients With Distal Radius Fractures
Pain ControlDistal Radius Fracture ReductionPediatric Fractures
State University of New York at Buffalo50 enrolled1 locationNCT07120763
Recruiting
Phase 2Phase 3
Choline and Iron Deficiency
AnemiaPediatric Iron Deficiency
University of Minnesota300 enrolled1 locationNCT06527391
Recruiting
Phase 3
The Efficacy and Safety of Dapagliflozin in the Treatment of Hereditary Kidney Disease With Proteinuria in Children
Pediatric Hereditary Kidney Diseases
Children's Hospital of Fudan University44 enrolled1 locationNCT06890143
Recruiting
Phase 3
Study to Evaluate Safety and Efficacy of Different PANZYGA Dose Regimens in Pediatric Chronic Inflammatory Demyelinating Polyradiculoneuropathy (CIDP) Patients
Pediatric Chronic Inflammatory Demyelinating Polyneuropathy
Octapharma30 enrolled6 locationsNCT04929236
Recruiting
Phase 3
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Acute Lymphoblastic Leukemia, Pediatric
Martin Schrappe5,000 enrolled115 locationsNCT03643276
Recruiting
Phase 2Phase 3
POHCA Resuscitation: Evaluation of IM Epinephrine
Pediatric Out-of-Hospital Cardiac Arrest
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's284 enrolled1 locationNCT05166343
Recruiting
Phase 3
A Prospective Clinical Cohort Study on Stratified Treatment of Rhabdomyosarcoma Based on Risk Factors.
Pediatric CancerRhabdomyosarcoma
Yizhuo Zhang300 enrolled1 locationNCT06836492
Recruiting
Phase 2Phase 3
Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.
All Types of Pediatric Cancer
Universität Duisburg-Essen56 enrolled1 locationNCT04765020
Recruiting
Phase 3
Combined Immuno-chemotherapy for Patients With B-linear Acute Lymphoblastic Leukemia Diagnosed From 0 to 365 Days of Life (ALL-Baby-2021)
Acute Lymphoblastic Leukemia, PediatricALL, Infants
Federal Research Institute of Pediatric Hematology, Oncology and Immunology80 enrolled1 locationNCT05029531