Percutaneous Coronary Intervention (PCI) Clinical Trials

19 recruitingLast updated: June 18, 2026

There are 19 actively recruiting percutaneous coronary intervention (pci) clinical trials across 16 countries. Studies span Not Applicable, Phase 4, Phase 3. Top locations include Amsterdam, Netherlands, Zurich, Switzerland, Alicante, Alicante, Spain. Updated daily from ClinicalTrials.gov.


Percutaneous Coronary Intervention (PCI) Trials at a Glance

19 actively recruiting trials for percutaneous coronary intervention (pci) are listed on ClinicalTrialsFinder across 6 cities in 16 countries. The largest study group is Not Applicable with 8 trials, with the heaviest enrollment activity in Amsterdam, Zurich, and Alicante. Lead sponsors running percutaneous coronary intervention (pci) studies include Albert Schweitzer Ziekenhuis, Netherlands, Azienda Ospedaliera di Bolzano, and Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA).

Browse percutaneous coronary intervention (pci) trials by phase

Treatments under study

About Percutaneous Coronary Intervention (PCI) Clinical Trials

Looking for clinical trials for Percutaneous Coronary Intervention (PCI)? There are currently 16 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Percutaneous Coronary Intervention (PCI) trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Percutaneous Coronary Intervention (PCI) clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 119 of 19 trials

Recruiting
Not Applicable

Efficacy of Transcutaneous Auricular Vagus Nerve Stimulation on Alleviating Major Depressive Disorder in Patients With Acute Coronary Syndrome After Percutaneous Coronary Intervention:A Prospective, Double-Blind,Randomized Controlled Study

Depressive DisorderPercutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)+5 more
Jing Han120 enrolled1 locationNCT07454070
Recruiting

Advanced Invasive Diagnosis Strategy for Post-PCI Patients With Stable Coronary Syndromes Undergoing Coronary Angiography

Chronic Coronary SyndromeAngina, StablePercutaneous Coronary Intervention (PCI)+1 more
Fundacion Investigacion Interhospitalaria Cardiovascular246 enrolled5 locationsNCT07638137
Recruiting
Not Applicable

Hybrid Percutaneous Coronary Intervention Combining a Bioresorbable Scaffold With Drug-coated Balloons Versus a Conventional Drug-eluting Stent-based Strategy in Patients With Long and Diffuse Coronary Artery Disease

Coronary Artery DiseasePercutaneous Coronary Intervention (PCI)Diffuse Coronary Artery Disease
University Hospital, Geneva150 enrolled3 locationsNCT06710210
Recruiting

Artificial Intelligence Based Timing, Infarct Size and Outcomes in Acute Coronary Occlusion Myocardial Infarction

Coronary Arterial Disease (CAD)Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Azienda Ospedaliera di Bolzano1,500 enrolled1 locationNCT06910436
Recruiting

OPtimal stEnt Deployment stRategy oF Contemporary sTents - Registry to Evaluate Percutaneous Coronary Intervention Using Bioresorbable Scaffolds With Thinner-strut Construction and Guidance by intracOronary Imaging to REduce Scaffold Failure

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
Albert Schweitzer Ziekenhuis, Netherlands117 enrolled1 locationNCT06919562
Recruiting
Phase 4

Monotherapy With P2Y12 Inhibitors in Patients With Atrial fIbrillation Undergoing Supraflex Stent Implantation

Atrial Fibrillation (AF)Percutaneous Coronary Intervention (PCI)Oral Anticoagulation+1 more
Insel Gruppe AG, University Hospital Bern3,010 enrolled15 locationsNCT05955365
Recruiting
Not Applicable

Leave Nothing Behind Study Which Compares DCB With Bail Out BRS Versus BRS Strategy Alone

Percutaneous Coronary Intervention (PCI)Acute Coronary Syndrome (ACS)Drug-coated Balloon+1 more
Ceric Sàrl2,256 enrolled1 locationNCT07038408
Recruiting
Not Applicable

Orbital Atherectomy vs Intravascular Lithotripsy for the Treatment of Calcified Coronary Nodules (ORBIT-SHOCK).

Chronic Coronary SyndromeCoronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)+6 more
Spanish Society of Cardiology50 enrolled6 locationsNCT06736665
Recruiting
Phase 4

Prasugrel Monotherapy Reduced Dose in Acute and Chronic Coronary Syndrome Patients After Percutaneous Coronary Intervention (PROMOTE)

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
J.P.S Henriques300 enrolled1 locationNCT06916520
Recruiting
Not Applicable

Aerobic Exercise-induced Effect on Endothelial Function in Patients With Ischaemic Heart Disease

Cardiorespiratory FitnessAcute Myocardial InfarctionAngina, Stable+3 more
Instituto de Investigación Sanitaria y Biomédica de Alicante132 enrolled2 locationsNCT06788275
Recruiting

Drug-Coated Balloon Primary PCI in ST-Segment Elevation Myocardial Infarction

Myocardial Infarction (MI)STEMIST Elevation Myocardial Infarction+2 more
Medical University of Vienna300 enrolled1 locationNCT07436429
Recruiting

The 3D Stent Study

Coronary Artery DiseasePercutaneous Coronary Intervention (PCI)
CoreAalst BV200 enrolled4 locationsNCT06898021
Recruiting
Not Applicable

Optimal Strategy to Correct Stent underexpAnsion in Resistant Lesions

Coronary angioplastyCoronary Artery DiseaseCoronary Artery Disease (CAD)+10 more
University Hospital, Clermont-Ferrand80 enrolled2 locationsNCT07316504
Recruiting

Registry of Coronary Disease Outcomes Revascularizing With Drug-Coated Balloons

PaclitaxelACS (Acute Coronary Syndrome)CAD - Coronary Artery Disease+3 more
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)3,000 enrolled1 locationNCT07231835
Recruiting
Phase 4

Dual Antiplatelet Therapy Escalation From Standard-dose Clopidogrel to Low-Dose Prasugrel in Patients With High Bleeding and Ischemic Risk Undergoing PCI: A Prospective, Randomized Pharmacodynamic Study (TAILOR-BLEED-2)

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
University of Florida40 enrolled1 locationNCT07025148
Recruiting
Not Applicable

Medipixel XA-Assisted PCI in Coronary Artery Disease

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)
CHA University830 enrolled6 locationsNCT06985693
Recruiting

Double Kissing-crush vs Controlled Balloon-crush Techniques For Complex Coronary Bfurcation Lesions

Coronary Arterial Disease (CAD)Percutaneous Coronary Intervention (PCI)Bifurcation Coronary Disease
Istanbul Mehmet Akif Ersoy Educational and Training Hospital300 enrolled2 locationsNCT06931574
Recruiting
Not Applicable

Comparison of an Ultra-low Strut Thickness Everolimus-eluting Biodegradable Polymer Stent Versus Durable Polymer Everolimus-eluting Stents in Patients Treated with Percutaneous Coronary Intervention

Coronary Artery DiseasePercutaneous Coronary Intervention (PCI)Ischemia, Myocardial
Odense University Hospital3,150 enrolled3 locationsNCT06692140
Recruiting
Phase 3

Efficacy and Safety Study of Vicagrel in Patients With Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)

Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
Jiangsu vcare pharmaceutical technology co., LTD1,000 enrolled1 locationNCT06577519