Personality Disorder Clinical Trials

74 recruitingLast updated: June 18, 2026

There are 74 actively recruiting personality disorder clinical trials across 17 countries. Studies span Not Applicable, Phase 2, Phase 1. Top locations include Boston, Massachusetts, United States, Lund, Skåne County, Sweden, Heidelberg, Germany. Updated daily from ClinicalTrials.gov.


Personality Disorder Trials at a Glance

74 actively recruiting trials for personality disorder are listed on ClinicalTrialsFinder across 6 cities in 17 countries. The largest study group is Not Applicable with 33 trials, with the heaviest enrollment activity in Boston, Lund, and Heidelberg. Lead sponsors running personality disorder studies include Region Skane, Massachusetts General Hospital, and Tages Onlus.

Browse personality disorder trials by phase

Treatments under study

About Personality Disorder Clinical Trials

Looking for clinical trials for Personality Disorder? There are currently 6 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Personality Disorder trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Personality Disorder clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 74 trials

Recruiting
Phase 2

Mindfulness-based Neurofeedback to Augment Psychotherapy for Adults With Borderline Personality Disorder

Borderline Personality Disorder
Yale University150 enrolled1 locationNCT06446765
Recruiting

The Role of Gender in Borderline Personality Disorder

Borderline personality disorder (BPD)
University Hospital Heidelberg15 enrolled1 locationNCT07639957
Recruiting
Phase 1Phase 2

A Pilot Trial of One-Day Accelerated TMS and D-cycloserine in Suicidal Patients With Borderline Personality Disorder

Borderline personality disorder (BPD)
Mclean Hospital20 enrolled1 locationNCT07460947
Recruiting
Phase 1

A Study to Test How BI 3031185 is Tolerated by People With Borderline Personality Disorder or Attention-deficit/Hyperactivity Disorder

Attention Deficit Hyperactivity DisorderBorderline Personality Disorder
Boehringer Ingelheim96 enrolled9 locationsNCT07001475
Recruiting

Triage Survey for Psychiatry Research Eligibility

Major Depressive DisorderGeneralized Anxiety DisorderBorderline Personality Disorder
Adams Clinical20,000 enrolled6 locationsNCT05800925
Recruiting
Not Applicable

A Precision Medicine Approach to Target Engagement for Emotion Regulation

DepressionAnxietyEating Disorders+4 more
Matthew Southward, PhD390 enrolled1 locationNCT05651295
Recruiting

Medical Phenotyping of NHS General Adult Psychiatry (GAP) Inpatients

Schizophrenia DisordersPersonality DisordersDepression Disorders+1 more
University of Edinburgh100 enrolled1 locationNCT07398365
Recruiting
Not Applicable

Home-Based tDCS for Depression in BPD

Major Depressive Disorder (MDD)Borderline Personality Disorders
Ciusss de L'Est de l'Île de Montréal60 enrolled1 locationNCT06972368
Recruiting

Long-term Follow-up of Depressive Disorders in Psychiatric Care

DepressionPersonality DisordersAnhedonia+3 more
Region Skane415 enrolled2 locationsNCT07078227
Recruiting
Not Applicable

PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder

Borderline Personality DisorderRelatives
University Hospital Bispebjerg and Frederiksberg100 enrolled1 locationNCT06563466
Recruiting
Phase 2

Testing Interventions for Borderline Personality Disorder.

Borderline Personality Disorder
York University304 enrolled1 locationNCT06458933
Recruiting
Not Applicable

Neurostimulation Versus Therapy for Problems With Emotions

Eating DisordersAnxiety DisordersObsessive-Compulsive Disorder+12 more
Duke University240 enrolled1 locationNCT05712057
Recruiting
Not Applicable

Effectiveness of EMDR in Borderline Personality Disorder

Borderline Personality Disorder
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia56 enrolled1 locationNCT06493708
Recruiting
Not Applicable

Physical Activity in the Management of Personality Disorders

Borderline personality disorder (BPD)Avoidant Personality Disorders
Julie Midtgaard60 enrolled2 locationsNCT07341438
Recruiting
Phase 1Phase 2

Brain Signal Training to Enhance Affect Down-regulation

Borderline Personality Disorder
Central Institute of Mental Health, Mannheim164 enrolled6 locationsNCT06626789
Recruiting
Phase 2

MDMA in Borderline Personality Disorder

Borderline Personality Disorder
Yale University10 enrolled1 locationNCT06683014
Recruiting
Not Applicable

Internal Family Systems Therapy for Borderline Personality Disorder

Borderline personality disorder (BPD)
Waypoint Centre for Mental Health Care15 enrolled1 locationNCT07342907
Recruiting
Not Applicable

Cognitive Reappraisal Training for Borderline Personality (BPD)

Borderline Personality Disorder
Icahn School of Medicine at Mount Sinai130 enrolled1 locationNCT06772831
Recruiting
Not Applicable

Short Integrative And Neurocognitive Therapy For Young Adults With Borderline Personality Disorder

Borderline Personality Disorder
Centre Hospitalier Universitaire de Nīmes74 enrolled1 locationNCT05913544
Recruiting
Not Applicable

Treatment of Borderline Personality Disorder With rTMS

Borderline Personality DisorderBorderline PersonalityBPD - Borderline Personality Disorder
University of California, Los Angeles30 enrolled2 locationsNCT07197502