Proton Therapy Clinical Trials

9 recruiting

Proton Therapy Trials at a Glance

9 actively recruiting trials for proton therapy are listed on ClinicalTrialsFinder across 6 cities in 11 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Nice, Dresden, and Groningen. Lead sponsors running proton therapy studies include University of Aarhus, Institute of Hematology and Blood Transfusion, Czech Republic, and EBG MedAustron GmbH.

Browse proton therapy trials by phase

Treatments under study

About Proton Therapy Clinical Trials

Looking for clinical trials for Proton Therapy? There are currently 9 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Proton Therapy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Proton Therapy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 19 of 9 trials

Recruiting
Phase 1Phase 2

Proton-Based Total Marrow Irradiation for Allogeneic Transplantation in High-Risk AML/MDS

Proton TherapyAcute Myeloid Leukemia (AML)Myelodysplastic Neoplasm+2 more
Institute of Hematology and Blood Transfusion, Czech Republic16 enrolled2 locationsNCT07532824
Recruiting
Not Applicable

Preoperative, Proton- Radiotherapy Combined With Chemotherapy for Borderline Resectable Pancreatic Cancer

Pancreatic CancerProton Therapy
EBG MedAustron GmbH10 enrolled2 locationsNCT04894643
Recruiting

HUmanitas PROtontherapy (HU-PRO)

CancerProton Therapy
Istituto Clinico Humanitas500 enrolled1 locationNCT07317245
Recruiting
Not Applicable

Ultra-Hypofractionated vs. Moderately Hypofractionated Proton Therapy for Early Breast Cancer After Lumpectomy

Breast CancerProton Therapy
Shanghai Proton and Heavy Ion Center312 enrolled1 locationNCT07135661
Recruiting
Not Applicable

Virtual Reality for Children in Radiotherapy (REVER)

Proton TherapyVirtual RealityPediatric Cancer
Centre Antoine Lacassagne47 enrolled1 locationNCT04934293
Recruiting

Safety and Efficacy of IMPT or IMRT for Breast Cancer

Breast CancerProton TherapyIntensity Modulated Radiation Therapy+2 more
Ruijin Hospital500 enrolled1 locationNCT06826885
Recruiting
Phase 3

PROton Versus Photon Therapy for Esophageal Cancer - a Trimodality Strategy

Esophageal CancerProton TherapyRadiotherapy+1 more
University of Aarhus396 enrolled15 locationsNCT05055648
Recruiting
Phase 2

Proton Therapy for Locally Advanced Cervical Cancer

Radiotherapy Side EffectCervical CancerProton Therapy
University of Aarhus55 enrolled1 locationNCT06462378
Recruiting
Not Applicable

HYpofractionated, Dose-redistributed RAdiotherapy With Protons and Photons in HNSCC

Head and Neck Squamous Cell CarcinomaProton TherapyRadiotherapy+2 more
Joris B.W. Elbers100 enrolled1 locationNCT05364411