Phase 2 Pulmonary Disease Clinical Trials

41 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 41 trials

Recruiting
Phase 2

A Study to Assess the Safety, Tolerability, PK and PD of WIN378 in Participants With Moderate - Severe COPD

COPD, Chronic Obstructive Pulmonary Disease
Windward Bio105 enrolled3 locationsNCT07646587
Recruiting
Phase 2

A Study to Evaluate the Efficacy and Safety of RSS0343 Tablets in Patients With Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease
Reistone Biopharma Company Limited300 enrolled1 locationNCT07349524
Recruiting
Phase 2

A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca987 enrolled366 locationsNCT07082738
Recruiting
Phase 2

Oral Sildenafil for Exercise Capacity, Dyspnea and Cardiopulmonary Function in COPD

Chronic Obstructive Pulmonary Disease
University of Alberta160 enrolled1 locationNCT05061368
Recruiting
Phase 2

The Cardiovascular Consequences of Sleep Apnea Plus COPD (Overlap Syndrome)

Chronic Obstructive Pulmonary DiseaseObstructive Sleep ApneaOverlap Syndrome
University of California, San Diego240 enrolled1 locationNCT05237505
Recruiting
Phase 2

A Phase IIb Ensifentrine-glycopyrrolate Fixed-dose Combination Dose Ranging Study in Subjects With COPD

Chronic Obstructive Pulmonary Disease
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA480 enrolled57 locationsNCT07016412
Recruiting
Phase 2

Breathe Easier With Tadalafil Therapy for Dyspnea in COPD-PH

Chronic Obstructive Pulmonary DiseaseDyspneaPulmonary Hypertension
VA Office of Research and Development126 enrolled5 locationsNCT05937854
Recruiting
Phase 2Phase 3

Finding the Optimal Regimen for Mycobacterium Abscessus Treatment

Pulmonary Disease Due to Mycobacteria (Diagnosis)
The University of Queensland300 enrolled50 locationsNCT04310930
Recruiting
Phase 2

Psilocybin Therapy for Psychological Distress in Palliative Patients

COPD, Chronic Obstructive Pulmonary DiseaseMajor Depressive Disorder (MDD)ALS (Amyotrophic Lateral Sclerosis)+2 more
University Medical Center Groningen108 enrolled4 locationsNCT06782724
Recruiting
Phase 1Phase 2

Feasibility of Semaglutide in Advanced Lung Disease

ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 2

Phase II Study of RC1416 Injection in COPD

Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)
Nanjing RegeneCore Biotech Co., Ltd.180 enrolled41 locationsNCT07402551
Recruiting
Phase 1Phase 2

Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa

Chronic Obstructive Pulmonary Disease
University Hospital, Grenoble24 enrolled1 locationNCT04427826
Recruiting
Phase 2

Inhaled Treprostinil for Dyspnea and Exercise Intolerance in Mild COPD

COPD, Chronic Obstructive Pulmonary Disease
University of Alberta20 enrolled1 locationNCT06969573
Recruiting
Phase 2Phase 3

A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease

Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer1,156 enrolled32 locationsNCT07363694
Recruiting
Phase 1Phase 2

cfMSC Stem Cell Therapy Targeting COPD

Chronic Obstructive Pulmonary Disease (COPD)
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT07477600
Recruiting
Phase 2

A Phase II Clinical Trial on the Efficacy and Safety of TQC3721 Inhalation Powder

Pulmonary Disease, Chronic Obstructive
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.195 enrolled29 locationsNCT07252908
Recruiting
Phase 2

Umbilical Cord Mesenchymal Stem Cells as Adjuvant Therapy in Group E COPD Patients

Chronic Obstructive Pulmonary Disease (COPD)
RSUP Persahabatan20 enrolled1 locationNCT07441226
Recruiting
Phase 2

Clinical Trial of Omalizumab for Allergen Sensitized and Exposed Individuals With COPD

Chronic Obstructive Pulmonary Disease (COPD)Allergies
Johns Hopkins University334 enrolled23 locationsNCT07059091
Recruiting
Phase 2

A Study to Assess the Efficacy and Safety of Verekitug in Participants With COPD

Chronic Obstructive Pulmonary Disease
Upstream Bio Inc.666 enrolled325 locationsNCT06981078
Recruiting
Phase 2

A Phase II Study of CM326 in Subjects With Moderate to Severe Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease
CSPC ZhongQi Pharmaceutical Technology Co., Ltd.318 enrolled1 locationNCT07418736