Phase 4 Pulmonary Disease Clinical Trials

16 recruitingPhase 4

What is a Phase 4 trial?

Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.

Showing 116 of 16 trials

Recruiting
Phase 4

A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.

Chronic Obstructive Pulmonary Disease
Sanofi218 enrolled58 locationsNCT07053423
Recruiting
Phase 4

A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation

Chronic Obstructive Pulmonary DiseaseHyperinflation
AstraZeneca56 enrolled7 locationsNCT07073950
Recruiting
Phase 4

Comparing Hydrocortisone and Prednisolone for Acute Exacerbation of Chronic Obstructive Pulmonary Disease (AECOPD)

Chronic Obstructive Pulmonary Disease (COPD)
Copenhagen Respiratory Research2,000 enrolled14 locationsNCT06892210
Recruiting
Phase 4

Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels

Chronic Obstructive Pulmonary Disease
Maria Joyera Rodríguez135 enrolled6 locationsNCT06334575
Recruiting
Phase 4

Short-term Antibiotic Therapy in Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao188 enrolled6 locationsNCT07213765
Recruiting
Phase 4

Short-term Bactericidal Effect of Contezolid in MAC-PD

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao188 enrolled3 locationsNCT07084402
Recruiting
Phase 4

Prevention of Recurrence With Cordyceps Sinensis in Mycobacterium Avium Complex Pulmonary Disease

Mycobacterium Avium Complex Pulmonary Disease
Bin Cao300 enrolled6 locationsNCT07174076
Recruiting
Phase 4

Chest CT Using Low-concentration Iodine Contrast Media

Pulmonary Disease
Jung Im Jung370 enrolled6 locationsNCT05967117
Recruiting
Phase 4

Chronic Airway Disease, Mucus Rheology and Exacerbations

Chronic Obstructive Pulmonary Disease
University Hospital, Montpellier72 enrolled3 locationsNCT04339270
Recruiting
Phase 4

Optimising Azithromycin Prevention Treatment in COPD to Reduce Exacerbations

Chronic Obstructive Pulmonary Disease
Dr Ian B Wilkinson1,311 enrolled1 locationNCT05772013
Completed
Phase 4

Trialling a double-dose of influenza vaccine to examine the efficacy of the influenza vaccination in patients with chronic obstructive pulmonary disease (COPD)

Influenza viral diseaseChronic Obstructive Pulmonary Disease
Princess Alexandra Hospital43 enrolled2 locationsACTRN12620000954921
Completed
Phase 4

Investigating the effectiveness of nebulised Pulmozyme (dornase alfa) in reducing inflammation in chronic airway disease

AsthmaChronic Obstructive Pulmonary Disease (COPD)
University of Newcastle30 enrolled1 locationACTRN12617000395336
Terminated
Phase 4

Efficacy of umeclidinium bromide and vilanterol (UMEC/VI) for the slowing of chronic obstructive pulmonary disease (COPD) development in smokers

Chronic Obstructive Pulmonary Disease
The George Institute for Global Health320 enrolled5 locationsACTRN12616001208493
Not Yet Recruiting
Phase 4

Simvastatin treatment for patients with Chronic obstructive pulmonary disease (COPD) and elevated C-reactive protein (CRP).

Chronic Obstructive Pulmonary Disease (COPD)Elevated CRP
Associate Professor Robert Young48 enrolled1 locationACTRN12615000491561
Completed
Phase 4

Managing Inflammation in Chronic Obstructive Pulmonary Disease (COPD) [Mi COPD]

Chronic Obstructive Pulmonary Disease (COPD)
John Hunter Hospital134 enrolled1 locationACTRN12613000046707
Completed
Phase 4

The effect of bronchodilators on lung ventilation in chronic obstructive pulmonary disease

Chronic Obstructive Pulmonary Disease
The Woolcock Institute of Medical Research15 enrolled1 locationACTRN12607000482460