Phase 1 Pulmonary Disease Clinical Trials
16 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–16 of 16 trials
Recruiting
Phase 1Phase 2
Feasibility of Semaglutide in Advanced Lung Disease
ObesityChronic Obstructive Pulmonary DiseaseInterstitial Lung Disease+2 more
University of Pennsylvania8 enrolled1 locationNCT05746039
Recruiting
Phase 1Phase 2
Efficacy of Morphine in Reducing the Rate of Early Non-Invasive Ventilation Failure in Acute Exacerbation of Chronic Obstructive Pulmonary Disease, Phase I/IIa
Chronic Obstructive Pulmonary Disease
University Hospital, Grenoble24 enrolled1 locationNCT04427826
Recruiting
Phase 1Phase 2
A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease
Chronic Obstructive Pulmonary DiseaseNon-cystic Fibrosis Bronchiectasis
Genentech, Inc.128 enrolled7 locationsNCT06603246
Recruiting
Phase 1Phase 2
cfMSC Stem Cell Therapy Targeting COPD
Chronic Obstructive Pulmonary Disease (COPD)
Shenzhen Geno-Immune Medical Institute30 enrolled1 locationNCT07477600
Recruiting
Phase 1
A Clinical Study to Evaluate the Safety, Tolerability and Pharmacokinetic Profile of TQC3302 Inhalation Spray in Healthy Adult Subjects
Chronic Obstructive Pulmonary Disease
Chia Tai Tianqing Pharmaceutical (Guangzhou) Co., Ltd.57 enrolled1 locationNCT07267130
Recruiting
Phase 1
A Study of BBT002 in Healthy Volunteers (HVs) and in Patients With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD)
Bambusa Therapeutics68 enrolled11 locationsNCT07288554
Recruiting
Phase 1
: Vascular Function in Health and Disease
Heart FailureHypertensionChronic Obstructive Pulmonary Disease+1 more
Russell Richardson420 enrolled1 locationNCT02966665
Recruiting
Phase 1
A Study for GSK3862995B in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline130 enrolled32 locationsNCT06154837
Recruiting
Phase 1
A Study of BBT002 in Healthy Volunteers (HVs) and in Adult Patients With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Bambusa Therapeutics98 enrolled1 locationNCT06944925
Recruiting
Phase 1
Safety of Cultured Allogeneic Adult Umbilical Cord Derived Mesenchymal Stem Cells for Pulmonary Diseases
AsthmaChronic Obstructive Pulmonary DiseasePulmonary Disease
The Foundation for Orthopaedics and Regenerative Medicine20 enrolled1 locationNCT05147688
Recruiting
Phase 1
A Clinical Study of TQC3721 Inhalation Powder in Patients With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Chia Tai Tianqing Pharmaceutical Group Co., Ltd.72 enrolled1 locationNCT06748079
Recruiting
Phase 1Phase 2
Hyper Polarized Xenon-129 MRI vs Xenon-133 Scintigraphy
Chronic Obstructive Pulmonary Disease
University of Virginia30 enrolled1 locationNCT03331302
Completed
Phase 1
Comparative assessment of the absorption of a generic formulation of tiotropium test product 1 and tiotropium test product 2 against the innovator Spiriva HandiHaler conducted under fasting conditions in healthy male and female volunteers
Bioavailability study conducted in healthy volunteers comparing three formulations of tiotropium with no health condition or problem studied.
Tiotropium is a long-acting, antimuscarinic agent, which is often referred to as an anticholinergic and is used to make breathing easier for people with Chronic Obstructive Pulmonary Disease (COPD).
Zenith Technology Corp Ltd24 enrolled1 locationACTRN12615000073505
Completed
Phase 1
Single Ascending Dose and Multiple Ascending Dose Phase I study of PXS-4728A Administered Orally in Healthy Adult Males.
Chronic Obstructive Pulmonary DiseaseCystic Fibrosis
Pharmaxis Ltd.72 enrolled1 locationACTRN12614001326684
Completed
Phase 1
Randomised trial comparing controlled oxygen therapy with high-flow oxygen therapy in the treatment of patients with Acute Exacerbations of Chronic Obstructive Pulmonary Disease (AECOPD) in the pre-hospital setting
Chronic Obstructive Pulmonary Disease (COPD)
Associate Professor Richard Wood-Baker150 enrolled1 locationACTRN12609000236291
Completed
Phase 1
Trial of nurse and GP partnership for care of COPD
Chronic Obstructive Pulmonary Disease (COPD)
Prof Nicholas Zwar400 enrolled1 locationACTRN12606000304538