Phase 3 Pulmonary Disease Clinical Trials
21 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 21 trials
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled166 locationsNCT07190209
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled188 locationsNCT07190222
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled268 locationsNCT06878261
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled298 locationsNCT06883305
Recruiting
Phase 3
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline960 enrolled159 locationsNCT06961214
Recruiting
Phase 3
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Hoffmann-La Roche1,290 enrolled462 locationsNCT05595642
Recruiting
Phase 3
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Hoffmann-La Roche2,000 enrolled483 locationsNCT05878769
Recruiting
Phase 2Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer1,156 enrolled32 locationsNCT07363694
Recruiting
Phase 3
Trial to Determine Effective Aspirin Dose in COPD
Pulmonary Disease, Chronic Obstructive
Johns Hopkins University48 enrolled1 locationNCT05265299
Recruiting
Phase 3
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseasePulmonary Hypertension
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT05844462
Recruiting
Phase 3
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline1,196 enrolled6 locationsNCT07177339
Recruiting
Phase 3
Evaluation of 611 in Chinese Adults Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Pulmonary Disease, Chronic Obstructive (COPD)
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.594 enrolled4 locationsNCT07039669
Recruiting
Phase 3
Multi-Center Clean Air Randomized Controlled Trial in COPD
Chronic Obstructive Pulmonary Disease (COPD)
JHSPH Center for Clinical Trials770 enrolled11 locationsNCT06376994
Recruiting
Phase 3
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline981 enrolled15 locationsNCT06959095
Recruiting
Phase 2Phase 3
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment
Pulmonary Disease Due to Mycobacteria (Diagnosis)
The University of Queensland300 enrolled50 locationsNCT04310930
Recruiting
Phase 3
A Study to Evaluate the Safety and Efficacy of HL231 Solution for Inhalation in Patients with COPD
Chronic Obstructive Pulmonary Disease (COPD)
Haisco Pharmaceutical Group Co., Ltd.474 enrolled2 locationsNCT06643078
Recruiting
Phase 2Phase 3
Cell Therapy Associated With Endobronchial Valve
Chronic Obstructive Pulmonary Disease Severe
Hospital de Clinicas de Porto Alegre34 enrolled1 locationNCT04018729
Recruiting
Phase 3
Does blocking the body's own morphine-like chemicals during exercise change the perception of breathlessness?
Breathlessness during exercise in people with Chronic Obstructive Pulmonary Disease.
Flinders University- Deptment of Palliative and Supportive Services30 enrolled1 locationACTRN12611001182987
Completed
Phase 3
Microarray analysis following Anti-Inflammatory Interventions in Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary DiseaseEx-smokers with obstructive airway disease
Hunter New England Health Service15 enrolled1 locationACTRN12611000165987
Recruiting
Phase 3
Early inpatient-outpatient hospital-based pulmonary rehabilitation following hospitalisation for acute exacerbations of COPD: a randomised controlled study
Chronic Obstructive Pulmonary Disease (COPD)
Green Lane Research and Educational Fund100 enrolled1 locationACTRN12605000372684