Phase 3 Pulmonary Disease Clinical Trials
26 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–20 of 26 trials
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled213 locationsNCT07190222
Recruiting
Phase 3
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Chronic Obstructive Pulmonary Disease
Sanofi942 enrolled215 locationsNCT07190209
Recruiting
Phase 3
Long-term Safety and Tolerability of Tozorakimab in Patients With COPD and History of Exacerbations
Chronic Obstructive Pulmonary DiseaseCOPD
AstraZeneca82 enrolled13 locationsNCT07566195
Recruiting
Phase 3
A Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Phase III Study of HSK39004 Inhalation Powder for the Treatment of COPD
COPD, Chronic Obstructive Pulmonary Disease
Haisco Pharmaceutical Group Co., Ltd.376 enrolled1 locationNCT07583849
Recruiting
Phase 3
Non-invasive Ventilation or CPAP in OSA-COPD Following Admission for an Acute Hypercapnic Respiratory Failure
Chronic Obstructive Pulmonary Disease ExacerbationObstructive Sleep Apnea Exacerbation
Assistance Publique - Hôpitaux de Paris386 enrolled1 locationNCT07047092
Recruiting
Phase 3
A Study to Evaluate the Long-Term Safety of Astegolimab in Participants With Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease
Hoffmann-La Roche2,000 enrolled486 locationsNCT05878769
Recruiting
Phase 3
Analysis of Growth Differentiation Factor 15 (GDF-15), Mid Regional proAdrenomedullin (MR proADM), and Persepsin Levels in Patient in Acute Coronary Syndrome Patients With Pneumonia, With or Without Influenza Vaccination
PneumoniaCOPD, Chronic Obstructive Pulmonary Diseaseacute coronary syndromes (ACS)
University of Brawijaya60 enrolled1 locationNCT07604103
Recruiting
Phase 3
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
COPD, Chronic Obstructive Pulmonary Disease
AstraZeneca5,000 enrolled920 locationsNCT06283966
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled301 locationsNCT06883305
Recruiting
Phase 2Phase 3
Finding the Optimal Regimen for Mycobacterium Abscessus Treatment
Pulmonary Disease Due to Mycobacteria (Diagnosis)
The University of Queensland300 enrolled50 locationsNCT04310930
Recruiting
Phase 3
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00007)
Chronic Obstructive Pulmonary Disease (COPD)
AstraZeneca990 enrolled268 locationsNCT06878261
Recruiting
Phase 3
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline960 enrolled159 locationsNCT06961214
Recruiting
Phase 3
A Study to Evaluate Astegolimab in Participants With Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary Disease (COPD)
Hoffmann-La Roche1,290 enrolled462 locationsNCT05595642
Recruiting
Phase 2Phase 3
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Moderate to Severe Chronic Obstructive Pulmonary Disease
Pfizer1,156 enrolled32 locationsNCT07363694
Recruiting
Phase 3
Trial to Determine Effective Aspirin Dose in COPD
Pulmonary Disease, Chronic Obstructive
Johns Hopkins University48 enrolled1 locationNCT05265299
Recruiting
Phase 3
Tadalafil for Severe Pulmonary Hypertension Due to Chronic Obstructive Pulmonary Disease
Chronic Obstructive Pulmonary DiseasePulmonary Hypertension
Assistance Publique - Hôpitaux de Paris200 enrolled1 locationNCT05844462
Recruiting
Phase 3
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline1,196 enrolled6 locationsNCT07177339
Recruiting
Phase 3
Evaluation of 611 in Chinese Adults Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease
Pulmonary Disease, Chronic Obstructive (COPD)
Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.594 enrolled4 locationsNCT07039669
Recruiting
Phase 3
Multi-Center Clean Air Randomized Controlled Trial in COPD
Chronic Obstructive Pulmonary Disease (COPD)
JHSPH Center for Clinical Trials770 enrolled11 locationsNCT06376994
Recruiting
Phase 3
Depemokimab as an Extended treatmeNt Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA -1)
Pulmonary Disease, Chronic Obstructive
GlaxoSmithKline981 enrolled15 locationsNCT06959095