Rectal Neoplasms Malignant Clinical Trials

12 recruitingLast updated: June 17, 2026

There are 12 actively recruiting rectal neoplasms malignant clinical trials across 9 countries. Studies span Not Applicable, Phase 2, Phase 3. Top locations include Mie, Japan, Milan, Italy, Barcelona, Spain. Updated daily from ClinicalTrials.gov.


Rectal Neoplasms Malignant Trials at a Glance

12 actively recruiting trials for rectal neoplasms malignant are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 4 trials, with the heaviest enrollment activity in Mie, Milan, and Barcelona. Lead sponsors running rectal neoplasms malignant studies include Sun Yat-sen University, City of Hope Medical Center, and Chang Gung Memorial Hospital.

Browse rectal neoplasms malignant trials by phase

Treatments under study

About Rectal Neoplasms Malignant Clinical Trials

Looking for clinical trials for Rectal Neoplasms Malignant? There are currently 2 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Rectal Neoplasms Malignant trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Rectal Neoplasms Malignant clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 112 of 12 trials

Recruiting
Phase 2

Delayed Systemic Therapy Following Destructive Local Treatment of Pulmonary Oligometastases After No Evidence of Disease (NED) in Colorectal Cancer.

Colorectal Neoplasms Malignant
Shandong Cancer Hospital and Institute22 enrolled1 locationNCT06778382
Recruiting

Early Onset Colorectal Cancer Detection

Colorectal, CancerColorectal NeoplasmsColorectal Adenocarcinoma+5 more
City of Hope Medical Center400 enrolled13 locationsNCT06342401
Recruiting
Not Applicable

Smart Measurement of Circulating Tumor DNA

Colorectal NeoplasmsColorectal Neoplasms MalignantColorectal Neoplasms, Hereditary Nonpolyposis+1 more
Erasmus Medical Center50 enrolled2 locationsNCT06989814
Recruiting
Not Applicable

Simultaneous vs. Staged Resection of Colorectal Cancer With Synchronous Liver Metastases

Colorectal, CancerLiver MetastasesLiver Metastasis Colon Cancer+1 more
Oslo University Hospital80 enrolled1 locationNCT06200831
Recruiting

Early Detection of Advanced Adenomas and Colorectal Cancer

Colorectal, CancerColorectal NeoplasmsColorectal Adenocarcinoma+15 more
City of Hope Medical Center2,000 enrolled6 locationsNCT06342440
Recruiting
Phase 3

Localized Treatment Versus Palliative Chemotherapy in CRC Patients With 10 or More CRLM

Colorectal Neoplasms Malignant
Sun Yat-sen University117 enrolled1 locationNCT06208371
Recruiting
Phase 2

Evaluation of Irinotecan Liposome (II) Combined With 5-FU, LV, and Bevacizumab for mCRC

Colorectal Neoplasms Malignant
Affiliated Hospital of Nantong University30 enrolled1 locationNCT06643793
Recruiting
Not Applicable

Transanal Versus Laparoscopic Total Mesorectal Excision for Rectal Cancer

SurgeryRectal Neoplasms Malignant
Sun Yat-sen University1,114 enrolled16 locationsNCT02966483
Recruiting

Effect of Gut Microbiota and Its Metabolites on the Efficacy of Immunotherapy in Metastatic Colorectal Cancer

Colorectal Neoplasms Malignant
The First Hospital of Jilin University50 enrolled1 locationNCT06714903
Recruiting

FAPI in Rectal Cancer TNT

Rectal Neoplasms Malignant
Chang Gung Memorial Hospital99 enrolled1 locationNCT06157463
Recruiting

Factors Affecting the Results of Treatment of Patients With Colorectal Cancer

Colorectal, CancerColon CancerRectal Cancer+3 more
Immanuel Kant Baltic Federal University1,200 enrolled1 locationNCT06050447
Recruiting
Not Applicable

Postoperative Effects of Different Enterostomy Approaches

Colorectal, CancerColorectal Neoplasms MalignantIntestinal Neoplasms, Malignant
Fudan University300 enrolled1 locationNCT05853094