Reflux Clinical Trials

3 recruiting

Reflux Trials at a Glance

64 actively recruiting trials for reflux are listed on ClinicalTrialsFinder across 6 cities in 30 countries. The largest study group is Not Applicable with 30 trials, with the heaviest enrollment activity in Kansas City, Jacksonville, and Aurora. Lead sponsors running reflux studies include Mayo Clinic, Federal State Budgetary Scientific Institution "Federal Research Centre of Nutrition, Biotechnology, and Midwest Biomedical Research Foundation.

Browse reflux trials by phase

Treatments under study

About Reflux Clinical Trials

Looking for clinical trials for Reflux? There are currently 3 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Reflux trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Reflux clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 64 trials

Recruiting

Endoscopic Bariatric Therapies (EBTs): A Retrospective and Prospective Multicenter Registry

ObesityWeight LossGastro Esophageal Reflux+1 more
Weill Medical College of Cornell University9,999 enrolled1 locationNCT04494048
Recruiting
Not Applicable

Safety and Effectiveness of eGERD Device to Reduce Gastroesophageal Reflux Disease (GERD) Symptoms

GERD (Gastroesophageal Reflux Disease)
Gerd Care Medical Ltd84 enrolled4 locationsNCT06613438
Recruiting
Phase 3

Domperidone in Treating Patients With Gastrointestinal Disorders

Nausea and VomitingGastroparesisDyspepsia+4 more
M.D. Anderson Cancer Center200 enrolled1 locationNCT01696734
Recruiting

Study of Gut Microbiota Diversity in Children Aged 1-3 Years on Prolonged Antibiotic Prophylaxis for Grade 3 or Higher Vesicoureteral Reflux Compared With 2 Age-matched Control Groups

Vesicoureteral Reflux 3
Centre Hospitalier Universitaire de Nīmes150 enrolled2 locationsNCT05319067
Recruiting

Esophageal Cancer Risk Registry

Esophageal CancerEsophageal DiseasesEsophageal Achalasia+2 more
University of Pittsburgh7,000 enrolled1 locationNCT00260585
Recruiting
Not Applicable

Mechanistic and Clinical Outcomes of a Surgical Innovation Aimed at Minimizing GERD Associated With VSG (INNOVATE-VSG)

ObesityBariatric SurgeryGastroesophageal Reflux Disease+1 more
University of California, Irvine44 enrolled2 locationsNCT06783751
Recruiting
Not Applicable

Performance and Safety of Afluxin® in Patients With Gastroesophageal Reflux Disease

Gastroesophageal Reflux Disease (GERD)
Devintec Sagl208 enrolled7 locationsNCT06984484
Recruiting
Not Applicable

Validation of the C-mo System - Cough Monitoring

AsthmaChronic Obstructive Pulmonary DiseaseIdiopathic Pulmonary Fibrosis+5 more
Cough Monitoring Medical Solutions300 enrolled8 locationsNCT05989698
Recruiting

Study on Hydrotalcite for Relief of Acid Symptoms Due to Acid Rebound After Stopping Long-Term PPI Therapy

Gastroesophageal Reflux
Bayer167 enrolled2 locationsNCT07291700
Recruiting
Not Applicable

Proximal Gastrectomy Anterior Anastomosis With Pyloroplasty Versus Esophagogastric Anastomosis for Gastric Cancer

Gastric CancerProximal Gastric AdenocarcinomaGastroesophageal Reflux Disease
Nanchong Central Hospital60 enrolled1 locationNCT05514769
Recruiting
Not Applicable

Evaluating Medication Adherence of Patients With Gastroesophageal Reflux Disease With Support of the Smartphone Application GERDCare

GERD (Gastroesophageal Reflux Disease)
Institute of Gastroenterology and Hepatology, Vietnam380 enrolled1 locationNCT07125521
Recruiting
Not Applicable

Compassionate Use of Domperidone for Refractory Gastroparesis

GastroparesisGastroesophageal RefluxGERD
Jose Cocjin20 enrolled1 locationNCT04699591
Recruiting

Clinical Utility of WATS3D: A 5-Year Prospective Study

Barrett EsophagusEsophageal DiseasesGastro Esophageal Reflux+1 more
CDx Diagnostics90,000 enrolled1 locationNCT04312633
Recruiting

Prevalence of Symptomatic Gastroesophageal Reflux Disease in Czech Children (Czech GERDKids)

Gastro Esophageal Reflux
University Hospital, Motol1,000 enrolled1 locationNCT07482969
Recruiting
Not Applicable

External UES Band (Shaker Pressure Band) and GERD

Gastroesophageal Reflux
Medical College of Wisconsin350 enrolled1 locationNCT05697393
Recruiting
Not Applicable

Post-sleeve Gastrectomy Gastroesophageal Reflux Disease Prediction

Gastroesophageal RefluxSleeve GastrectomyBariatric Surgery Complication
Mayo Clinic200 enrolled2 locationsNCT04411823
Recruiting
Not Applicable

Anti-Reflux Endoscopic TX Using APC (AREA) in GERD Patients: (The AREA Study)

Gastro Esophageal Reflux
Midwest Veterans' Biomedical Research Foundation36 enrolled1 locationNCT05570448
Recruiting
Not Applicable

A Study of Breath Testing for Small Intestinal Bacterial Overgrowth

Gastroesophageal RefluxRegurgitationHeartburn
Mayo Clinic50 enrolled1 locationNCT05976165
Recruiting
Phase 3

Spinal Morphine or Intravenous Lidocaine in Robot-assisted Upper Urologic Surgery

Ureter CancerRenal CancerOther Specified Disorders of Kidney and Ureter+5 more
Hans Bahlmann220 enrolled3 locationsNCT06349668
Recruiting

Efficacy Of Hiatal Closure For GERD

Gastro Esophageal Reflux
University of Chicago40 enrolled1 locationNCT06280664