Replacement Clinical Trials

1 recruitingLast updated: May 5, 2026

There are 164 actively recruiting replacement clinical trials across 52 countries. Studies span Not Applicable, Phase 4, Phase 3, Phase 2. Top locations include Beijing, Beijing Municipality, China, Bordeaux, France, Beijing, China. Updated daily from ClinicalTrials.gov.


Replacement Trials at a Glance

164 actively recruiting trials for replacement are listed on ClinicalTrialsFinder across 6 cities in 52 countries. The largest study group is Not Applicable with 65 trials, with the heaviest enrollment activity in Beijing, Bordeaux, and Beijing. Lead sponsors running replacement studies include Insel Gruppe AG, University Hospital Bern, Austin Health, and Aarhus University Hospital.

Browse replacement trials by phase

Treatments under study

About Replacement Clinical Trials

Looking for clinical trials for Replacement? There are currently 1 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Replacement trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Replacement clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 120 of 164 trials

Recruiting
Not Applicable

Binaural Beats for Postoperative Pain and Anxiety Reduction

AnxietyTotal Hip Arthroplasty (THA)Total Knee Replacement+6 more
University of Miami50 enrolled1 locationNCT07437469
Recruiting
Not Applicable

Prolonged Chest Tube Treatment to Reduce Rates of Atrial Fibrillation Following Cardiac Surgery

Coronary Arterial Disease (CAD)Valve ReplacementAortic Surgery
Region Skane624 enrolled1 locationNCT06800781
Recruiting
Not Applicable

Menopause Effects on Cortico-reticular Functioning

MenopauseHormone Replacement Therapy
University of Jyvaskyla20 enrolled1 locationNCT07500922
Recruiting
Phase 4

Patient Quality of Recovery After TAVR With Different Sedation Regimens

Aortic Valve StenosisTranscatheter Aortic Valve Replacement (TAVR)
David Lyubashevsky126 enrolled1 locationNCT07556523
Recruiting
Not Applicable

Effect of Physical Therapy Rehabilitation on Gait and Plantar Pressure in Patients After Total Knee Replacement

Knee OsteoarthritisTotal Knee Replacement
Jouf University30 enrolled1 locationNCT07556003
Recruiting
Not Applicable

BiFeS vs. iPACK in Postoperative Knee Arthroplasty Analgesia

Pain, PostoperativeArthroplasty Replacement, KneeAnesthesia Regional
Amasya University88 enrolled1 locationNCT07360392
Recruiting
Phase 3

Suzetrigine for Treatment and Reduction of Intense Discomfort After knEe Replacement PAIN

Total knee replacement surgeryPost Operative Pain
Icahn School of Medicine at Mount Sinai235 enrolled1 locationNCT07548385
Recruiting
Not Applicable

Community Health Workers in an Interdisciplinary Outpatient CKD Clinic to Optimize Social Care Navigation, Patient Engagement, and Home Dialysis Utilization

Kidney Replacement Therapy
Montefiore Medical Center106 enrolled1 locationNCT06925776
Recruiting

Ischemic And Bleeding Risk Assessment After TAVR

Aortic Valve StenosisTranscatheter Aortic Valve Replacement
Niguarda Hospital2,500 enrolled12 locationsNCT06000943
Recruiting

COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)

Aortic Valve StenosisTranscatheter Aortic Valve Replacement
Niguarda Hospital100 enrolled1 locationNCT05779787
Recruiting
Phase 2

Cannabidiol for Postoperative Opioid Reduction in Primary Total Knee Arthroplasty

Knee Replacement SurgeryOsteoarthritis, Knee
Chad Brummett380 enrolled2 locationsNCT06234631
Recruiting
Phase 3

Safety Evaluation of Prismocitrate 18 in Patients Receiving CRRT

Acute Kidney Injury (AKI)Regional Citrate Anticoagulation (RCA)Continuous Renal Replacement Therapy (CRRT)
Vantive Health LLC40 enrolled14 locationsNCT05399537
Recruiting
Phase 2

Comparison of Anticoagulant Effects of Different Doses of Nafamostat in Continuous Renal Replacement Therapy (CRRT) in the Intensive Care Unit (ICU)

Continuous Renal Replacement Therapy (CRRT)
Zhujiang Hospital92 enrolled1 locationNCT07469072
Recruiting
Not Applicable

Liposomal vs Conventional Oral Iron After Sleeve Gastrectomy

İron Deficiency AnemiaLiposomal Iron ReplacementConventional Iron Replacement
Medeni Şermet70 enrolled1 locationNCT07366502
Recruiting
Not Applicable

Arch-Clamping Technique Under Mild Hypothermia in Treating With Acute Type A Aortic Dissection

HypothermiaAcute Type A Aortic DissectionTotal Aortic Arch Replacement+2 more
Beijing Anzhen Hospital306 enrolled1 locationNCT07150559
Recruiting
Not Applicable

Multimodal Prehabilitation of Frail Patients Undergoing Elective Knee or Hip Replacement

PrehabilitationFrailty SyndromeArthroplasties, Knee Replacement
University of Iceland50 enrolled1 locationNCT07465159
Recruiting
Not Applicable

Cold and Compression Post TKA

Primary Osteoarthritis Patients Scheduled for Total Knee Replacement Surgery
Ochsner Health System90 enrolled1 locationNCT07023185
Recruiting
Not Applicable

Validation of a Regional Citrate Anticoagulation Protocol in Critically Ill Patients on Continuous Renal Replacement Therapy

Acute Kidney InjuryICU PatientsContinuous Renal Replacement Therapy (CRRT)+1 more
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau43 enrolled1 locationNCT07514650
Recruiting
Not Applicable

Robotic Transjugular Transcatheter Tricuspid Valve Replacement

Tricuspid Regurgitation (TR)Transcatheter Valve ReplacementValvular Heart Diseases
Prince of Wales Hospital, Shatin, Hong Kong10 enrolled1 locationNCT07516145
Recruiting

Characteristics of Persistent Pain Composition Following Total Hip or Knee Arthroplasty: a Descriptive Study

Survey and QuestionnairePain (Visceral, Somatic, or Neuropathic)Hip Arthroplasty Replacement+1 more
Rigshospitalet, Denmark100 enrolled1 locationNCT07110324