Phase 4 Replacement Clinical Trials
28 recruitingPhase 4
What is a Phase 4 trial?
Phase 4 trials, also called post-marketing studies, are conducted after a treatment has been approved and is available to the public. They monitor long-term effectiveness and safety in a broader population.
Showing 1–20 of 28 trials
Recruiting
Phase 4
Patient Quality of Recovery After TAVR With Different Sedation Regimens
Aortic Valve StenosisTranscatheter Aortic Valve Replacement (TAVR)
David Lyubashevsky126 enrolled1 locationNCT07556523
Recruiting
Phase 4
Intravenous Dexamethasone Administration in Patients Undergoing Total Shoulder Arthroplasty
Arthroplasty, Replacement, Shoulder
Christian Candrian74 enrolled1 locationNCT04507412
Recruiting
Phase 4
Comparing the Safety and Effectiveness of Different Doses of Morphine Administered in Spinal Anethesia for Pain Relief After Hip Replacement Surgery
Anesthesia, SpinalAnalgesics, OpioidAdverse Anesthesia Outcome+1 more
Medical University of Silesia120 enrolled3 locationsNCT06878014
Recruiting
Phase 4
TRanscAtheter TreatMent of PurE Aortic Regurgitation With VitaFlow Liberty System
AORTIC VALVE DISEASESTranscatheter Aortic Valve Replacement (TAVR)aortic regurgitation
Ruijin Hospital120 enrolled4 locationsNCT06818084
Not Yet Recruiting
Phase 4
TRIAD: Trial for Reducing Infection After Arthroplasty with Dilute Povidone-Iodine
End Stage ArthritisOsteoarthritisTotal Knee Replacement
Australian National University5,460 enrolled69 locationsACTRN12626000076370
Recruiting
Phase 4
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
Total Knee Replacement
Christian Candrian159 enrolled1 locationNCT04432012
Recruiting
Phase 4
Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality
Knee Replacement Surgeryhip replacement surgerySleep Quality+3 more
Peking University First Hospital154 enrolled2 locationsNCT05950646
Recruiting
Phase 4
Albumin To Enhance Recovery After Acute Kidney Injury
renal replacement therapyAcute Kidney InjuryCritical Illness+1 more
Ottawa Hospital Research Institute856 enrolled16 locationsNCT04705896
Recruiting
Phase 4
CT TAVR Abdomen Study
Transcatheter Aortic Valve Replacement
University of Maryland, Baltimore164 enrolled1 locationNCT05758701
Recruiting
Phase 4
Comparison of Two Collagen Membranes for Bone Augmentation Around Dental Implants Restored with Monolithic Zirconia Single Crowns
Tooth ExtractionTooth Replacement
Dr. med. dent. Malin Strasding68 enrolled1 locationNCT06724783
Recruiting
Phase 4
Determining Dose Equivalence Between Oral and Transdermal Estrogen Treatment in Women With Turner Syndrome
Estrogen DeficiencyTurner SyndromeHypogonadism; Ovarian+2 more
Aarhus University Hospital50 enrolled1 locationNCT06544473
Recruiting
Phase 4
Long Term Effects of Oral Versus Transdermal Estrogen Replacement Therapy in Turner Syndrome
Estrogen DeficiencyTurner SyndromeHypogonadism; Ovarian+2 more
Aarhus University Hospital50 enrolled1 locationNCT06570460
Recruiting
Phase 4
Renal Outcomes in the Early Use of Vasopressin in the Treatment of Septic Shock
Septic ShockRenal Function Replacement
Azienda Usl di Bologna264 enrolled1 locationNCT06471231
Recruiting
Phase 4
Tapentadol vs Tramadol in Total Knee Arthroplasty
Post Operative PainChronic PainTotal Knee Replacement
University of Thessaly96 enrolled1 locationNCT06269770
Recruiting
Phase 4
Effectiveness of Combined Tobacco Treatment in Hospitalized Subjects
Tobacco SmokingNicotine AddictionNicotine Withdrawal+2 more
National Institute of Respiratory Diseases, Mexico134 enrolled1 locationNCT06254001
Recruiting
Phase 4
Reduced Opioids After Total Joint Replacement Surgery (REPAIRS): A pilot randomised controlled trial
Total knee replacement surgery
Royal Prince Alfred Hospital50 enrolled1 locationACTRN12623001070628
Not Yet Recruiting
Phase 4
A comparison of two techniques for pain relief following Knee Replacement Surgery
Knee Replacement Surgery
Mater and St Vincents Health64 enrolled1 locationACTRN12619000364178
Completed
Phase 4
New nerve block to improve pain relief after hip replacement
Hip ReplacementPainAnalgesia
Dr Mark Lennon64 enrolled1 locationACTRN12619000071123
Completed
Phase 4
Impact of Intra-Articular Local Anesthetic Injection versus Femoral Nerve Block for Post-Operative Analgesia in Total Knee Arthroplasty.
ASA 1 or 2 patient posted for primary elective total knee replacementknee arthritis posted for elective total knee replacement
Shahid Adeel60 enrolled1 locationACTRN12616001380482
Completed
Phase 4
Does infiltration of local anaesthesia improve recovery after anterior hip replacement?
total hip replacementlocal infiltration analgesia
Dr Nicole Tan160 enrolled1 locationACTRN12615000844549