Phase 2 REST Clinical Trials

21 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 21 trials

Recruiting
Phase 2

Efficacy of Early Intravenous High-dose Vitamin C in Post-cardiac Arrest Shock.

Cardiac Arrest
Centre Hospitalier de Bethune234 enrolled14 locationsNCT05817851
Recruiting
Phase 2Phase 3

A Self-Controlled Study on the Treatment of Restless Legs Syndrome in Uremia With Dipyridamole

Restless Leg Syndrome Due to Uraemia
Yunfeng Xia80 enrolled1 locationNCT07199504
Recruiting
Phase 2Phase 3

Resuscitation Enhancement to Avoid Rearrest Through Evidence-based Strategies in Prehospital Post-resuscitation Care

Out of Hospital Cardiac Arrest (OHCA)
Siriraj Hospital318 enrolled1 locationNCT07239908
Recruiting
Phase 2

Safety and Efficacy of Leucine-Restricted Diet Combined With Neoadjuvant Chemotherapy and Immunotherapy in Gastric Cancer

Gastric CancerLeucine-restricted Diet
Qilu Hospital of Shandong University108 enrolled1 locationNCT07537361
Recruiting
Phase 2

Statin Intervention for Severe Early-Onset Placental Insufficiency. (STATIN-PRE Trial)

Intrauterine Growth Restriction (IUGR)Preeclampsia (PE)Placental Insufficiency
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau154 enrolled2 locationsNCT07098975
Recruiting
Phase 2Phase 3

Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest

sudden deathVentricular FibrillationOut-of-hospital cardiac arrest+3 more
Gabriel Riva916 enrolled14 locationsNCT07174986
Recruiting
Phase 2

CardioPulmonary Resuscitation With Argon (CPAr) Trial

Cardiac Arrest, Out-Of-HospitalCardiac Arrest With Successful Resuscitation
Mario Negri Institute for Pharmacological Research120 enrolled9 locationsNCT05482945
Recruiting
Phase 2

PeRampanel fOr Status ePilEpticus pRophylaxis Post-cardiac Arrest

SeizuresStatus EpilepticusHeart Arrest
University of California, San Francisco52 enrolled1 locationNCT06401707
Recruiting
Phase 2

buRst-supprESsion TO Stop Refractory Status Epilepticus Post-cardiac Arrest

SeizuresStatus EpilepticusHypoxia-Ischemia, Brain+4 more
University of California, San Francisco30 enrolled1 locationNCT05851391
Recruiting
Phase 1Phase 2

Pilot Study of the α Prototype NIMBLE System: Feasibility, Safety, and Initial Performance in Non-Invasive Detection of Coronary In-Stent Restenosis

In-stent RestenosisStent FractureStent Complication
Nimble Diagnostics S.L.30 enrolled1 locationNCT06968858
Recruiting
Phase 2Phase 3

POHCA Resuscitation: Evaluation of IM Epinephrine

Pediatric Out-of-Hospital Cardiac Arrest
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's284 enrolled1 locationNCT05166343
Recruiting
Phase 2

Hypertonic Lactate After Cardiac Arrest

Cardiac ArrestIschemia Reperfusion InjuryAnoxic Brain Injury
Erasme University Hospital125 enrolled1 locationNCT05004610
Recruiting
Phase 2Phase 3

Gut Microbiome Profiles in Patients with Chemotherapy-induced Neuropathy in the RCT OzoParQT (NCT06706544).

Chemotherapy-induced Peripheral Neuropathy (CIPN)NumbnessParesthesia+1 more
Bernardino Clavo, MD, PhD42 enrolled1 locationNCT06799351
Recruiting
Phase 2Phase 3

Ozone Treatment in Paresthesia (Numbness, Tingling) Secondary to Chemotherapy-induced Peripheral Neuropathy

Chemotherapy-induced Peripheral Neuropathy (CIPN)NumbnessParesthesia+1 more
Bernardino Clavo, MD, PhD42 enrolled1 locationNCT06706544
Recruiting
Phase 2

Ketamine Sedation As Neuroprotective Agent Following Out-of-hospital Cardiac Arrest

Out of Hospital Cardiac Arrest (OHCA)
Christian Hassager282 enrolled2 locationsNCT06744361
Not Yet Recruiting
Phase 2

A Pilot, Safety, Efficacy and Feasibility Double-Blind Randomised Controlled Trial of Scp776 for Neuroprotection in Comatose Adults Resuscitated After Out-of-Hospital Cardiac Arrest

Cardiac Arrest
Austin Hospital40 enrolled1 locationACTRN12623001276640
Recruiting
Phase 2Phase 3

Surviving PEA in Roanoke (SPEAR) Study

Cardiac ArrestPulseless Electrical Activity
Carol Bernier342 enrolled1 locationNCT05283850
Completed
Phase 2

Clinical Study of New Intraocular Lens Design in Participants requiring Bilaterial Cataract Removal

Cataract extraction and artificial lens implantation for vision acuity restoration for far, intermediate and near vision with reduced need for further spectacle correction/dependence.
Abbott Medical Optics Inc50 enrolled1 locationACTRN12613000262707
Terminated
Phase 2

Feasibility study of normoxic versus hyperoxic therapy after cardiac arrest

Out-of-hospital cardiac arrest
Medical Research Institute of New Zealand42 enrolled1 locationACTRN12612001054808
Completed
Phase 2Phase 3

STRIDER (NZAus): A randomised placebo-controlled trial of a new therapy (sildenafil) to help growth in severely growth restricted fetuses at very early gestations.

Severe early onset fetal growth restriction
University of Auckland122 enrolled1 locationACTRN12612000584831