Phase 1 Sarcomas Clinical Trials
9 recruitingPhase 1
What is a Phase 1 trial?
Phase 1 trials test a new treatment in a small group of people for the first time. The primary goal is to evaluate safety, determine a safe dosage range, and identify side effects. These studies typically enroll 20 to 80 participants.
Showing 1–9 of 9 trials
Recruiting
Phase 1
Disulfiram With Copper Gluconate and Liposomal Doxorubicin in Treatment-Refractory Sarcomas
Relapsed Sarcomas
Case Comprehensive Cancer Center24 enrolled1 locationNCT05210374
Recruiting
Phase 1Phase 2
Study in Children and Adolescents of 177Lu-DOTATATE (Lutathera®) Combined With the PARP Inhibitor Olaparib for the Treatment of Recurrent or Relapsed Solid Tumours Expressing Somatostatin Receptor (SSTR) (LuPARPed).
ParagangliomaPheochromocytomaSolid Tumor Cancer+19 more
Fundación de investigación HM25 enrolled1 locationNCT06607692
Recruiting
Phase 1
Phase 1a/b Study of ZL-6201 Safety, PK, and Preliminary Efficacy in Sarcoma and Selected Tumors
Solid TumorsSarcomas
Zai Lab (Shanghai) Co., Ltd.180 enrolled5 locationsNCT07374848
Recruiting
Phase 1
A Study to Test the Safety, Tolerability and Effect of ZI-MA4-1 for Patients With Locally Advanced or Metastatic Solid Malignancies
Ovarian CancerHead and Neck CancerSynovial Sarcomas+1 more
Zelluna Immunotherapy AS9 enrolled2 locationsNCT07613723
Recruiting
Phase 1
A Phase I Trial of Combination Gemcitabine and Nab-Sirolimus in Advanced Leiomyosarcomas or Advanced Soft-Tissue Sarcomas With TSC2 or TSC1 Loss-of-function Mutations or Deletions
LeiomyosarcomaSoft Tissue Sarcomas
M.D. Anderson Cancer Center18 enrolled1 locationNCT06308419
Recruiting
Phase 1
Cabozantinib With Ifosfamide in Relapsed/Refractory Sarcomas
OsteosarcomaEwing SarcomaSarcomas
Children's Hospital of Philadelphia30 enrolled4 locationsNCT06156410
Recruiting
Phase 1
AOH1996 for the Treatment of Refractory Solid Tumors
Pancreatic CancerOvarian CancerNon-small Cell Lung Cancer+4 more
City of Hope Medical Center92 enrolled2 locationsNCT05227326
Recruiting
Phase 1Phase 2
Sequential Infusion of CD146-Targeted and HER2-Targeted CAR T Cells in Patients With Advanced Sarcomas
SarcomaSarcoma, SynovialSarcoma,Soft Tissue+6 more
Essen Biotech60 enrolled1 locationNCT07066982
Recruiting
Phase 1Phase 2
Multicohort Trial of Different Schemes of PM14 in Monotherapy and in Combination with Radiotherapy in Soft Tissue Sarcomas and Other Solid Tumor
Advanced Solid TumorAdvanced Soft Tissue SarcomaAdvanced L-sarcomas+2 more
Grupo Espanol de Investigacion en Sarcomas195 enrolled4 locationsNCT05146440