Sentinel Lymph Node Biopsy Clinical Trials

7 recruiting

Sentinel Lymph Node Biopsy Trials at a Glance

16 actively recruiting trials for sentinel lymph node biopsy are listed on ClinicalTrialsFinder across 6 cities in 9 countries. The largest study group is Not Applicable with 6 trials, with the heaviest enrollment activity in Milan, Antalya, and Bologna. Lead sponsors running sentinel lymph node biopsy studies include European Institute of Oncology, Isabelle Henskens, and Faculty of Medicine of Tunis.

Browse sentinel lymph node biopsy trials by phase

Treatments under study

About Sentinel Lymph Node Biopsy Clinical Trials

Looking for clinical trials for Sentinel Lymph Node Biopsy? There are currently 7 studies actively recruiting participants. Clinical trials offer access to new treatments before they are widely available, and every approved therapy in use today was first tested through a clinical trial.

Below you can browse trials, sign up for alerts when new Sentinel Lymph Node Biopsy trials open, and view eligibility criteria for each study. Each listing includes the study phase, locations, and enrollment details.

Frequently Asked Questions

Common questions about Sentinel Lymph Node Biopsy clinical trials

A clinical trial is a carefully designed research study that tests new medical treatments, drugs, devices, or approaches in human volunteers. Every approved medication and treatment available today was proven safe and effective through clinical trials.

All clinical trials are reviewed and approved by Institutional Review Boards (IRBs) — independent committees that evaluate patient safety. Trials follow strict protocols, and your health is monitored closely throughout. You can withdraw at any time.

Not necessarily. Many trials compare the new treatment against the current standard of care, meaning all participants receive active treatment. When placebos are used, they are typically combined with standard treatment, not given alone. The trial description will always specify the design.

Under the Affordable Care Act, most private insurers are required to cover routine patient care costs during a clinical trial. The sponsor typically covers the investigational treatment itself. Medicare also covers routine costs for qualifying trials.

Yes. Participation is completely voluntary. You can withdraw at any time, for any reason, without it affecting your access to standard medical care.

Each trial has specific eligibility criteria — including age, diagnosis, disease stage, prior treatments, and general health. Browse the trials listed above and check their eligibility sections. You can also contact the trial site directly to discuss your situation.

Showing 116 of 16 trials

Recruiting

Patent Blue SLN in Early Ovarian Cancer Prospective Study (FIGO I-II) Evaluating Patent Blue SLN Mapping. Injection Into IP/UO Ligaments in Situ. Goals: Assess Feasibility and Accuracy vs Standard Lymphadenectomy to Minimize Surgical Morbidity

Sentinel Lymph Node Biopsy (SLNB)Early Stage Ovarian Tumors
Faculty of Medicine of Tunis30 enrolled1 locationNCT07508306
Recruiting

Audit of Targeted Sentinel Node Biopsy (TSNB) in Patients With Limited Nodal Disease Undergoing Primary Surgery

Breast CancerSentinel Lymph Node Biopsy (SLNB)Axillary Lymph Nodes Dissection+1 more
University Hospitals of Derby and Burton NHS Foundation Trust200 enrolled12 locationsNCT07085442
Recruiting

Upfront Targeted Axillary Dissection for Luminal Breast Cancer With Limited Axillary Involvement

Sentinel Lymph Node Biopsy (SLNB)ALNDTargeted Axillary Dissection (TAD)
European Institute of Oncology150 enrolled14 locationsNCT07278726
Recruiting
Phase 3

No Axillary Surgical Treatment in Clinically Lymph Node Negative Patients on Ultrasonography After Neoadjuvant Chemotherapy

Breast CancerNeoadjuvant TherapySentinel Lymph Node Biopsy
Seoul National University Hospital464 enrolled1 locationNCT06704945
Recruiting
Not Applicable

Finding Sentinel Lymph Nodes During Mastectomy Using Indocyanine Green (INIGMA Study)

Breast CancerMastectomySentinel Lymph Node Biopsy (SLNB)+7 more
Isabelle Henskens90 enrolled2 locationsNCT07362485
Recruiting

Does Ultrasound Guidance Axillary Incision Improve Sentinel Lymph Node Detection in Breast Cancer?

Breast CarcinomaSentinel Lymph Node Biopsy
Antalya Training and Research Hospital40 enrolled1 locationNCT07338721
Recruiting
Not Applicable

Implementation of Indocyanine Green to Identify Sentinel Lymph Nodes During Surgery for Breast Cancer

Breast CancerSentinel Lymph Node Biopsy (SLNB)Sentinel Lymph Node Detection+6 more
Isabelle Henskens1,760 enrolled7 locationsNCT07146295
Recruiting
Not Applicable

Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in IBC

Sentinel Lymph Node Biopsy (SLNB)Invasive Breast CarcinomaNeoadjuvant Chemotherapy
European Institute of Oncology75 enrolled1 locationNCT07080944
Recruiting
Not Applicable

Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma

Sentinel Lymph NodeIndocyanine Green (ICG)Colon Cancer+9 more
Meander Medical Center341 enrolled1 locationNCT06652672
Recruiting

Rapid Assessment of Sentinel Lymph Node Metastasis Status Using a Pan-CK-targeting NIR-II Fluorescent Probe in Breast Cancer

Breast Cancer MetastaticSentinel Lymph Node Biopsy (SLNB)Sentinel Lymph Node+1 more
Yunnan Cancer Hospital60 enrolled1 locationNCT07154563
Recruiting
Not Applicable

Sentinel Node Biopsy Versus Limited Elective Neck Dissection in Early Cancers of Oral Cavity NoDe Negative

Sentinel Lymph Node Biopsy (SLNB)Sentinel Lymph NodeSentinel Lymph Node Biopsy+4 more
Tata Memorial Hospital508 enrolled3 locationsNCT05774483
Recruiting
Not Applicable

Comparison of Transvaginal Paracervical and Transperitoneal Approaches in Lymphadenectomy During v-NOTES Surgery for Patients Diagnosed With Endometrial Cancer

Endometrial CancerSentinel Lymph Node BiopsyMinimally Invasive Surgical Procedures+2 more
Saglik Bilimleri Universitesi Gazi Yasargil Training and Research Hospital52 enrolled1 locationNCT06870903
Recruiting
Phase 2

Photo-medicine-Guided Dual Approach for Reoperation of Sentinel Lymph Nodes in Locally Recurrent Breast Cancer Patients

Breast CancerSentinel Lymph Node Biopsy (SLNB)Locally Recurrent Breast Cancer+2 more
National Cancer Center, Korea30 enrolled1 locationNCT06780748
Recruiting

Axillary Sentinel Lymph Node Biopsy After Neoadjuvant Chemotherapy in Patients With Initial cN1 Breast Cancer

Sentinel Lymph Node Biopsy
Henan Cancer Hospital508 enrolled1 locationNCT06518135
Recruiting

The Role of Micrometastasis and Isolated Tumor Cells (ITCs) in Endometrial and Cervical Cancer. A Multicenter Study.

Cervical CancerEndometrial CancerSentinel Lymph Node+8 more
Fondazione IRCCS Istituto Nazionale dei Tumori, Milano500 enrolled1 locationNCT04403867
Recruiting
Phase 2Phase 3

A Randomized Trial Compared the Efficacy and Safety of Combined Use of Indocyanine Green Fluorescence and Methylene Blue Dye Versus Methylene Blue Dye alone for Sentinel Lymph Node Biopsy in Breast Cancer Patients

Sentinel Lymph Node Biopsy in Breast Cancer Patients
Peking University People's Hospital Breast Cancer Center100 enrolled1 locationACTRN12612000109808