Phase 2 Sepsis Clinical Trials

34 recruitingPhase 2

What is a Phase 2 trial?

Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.

Showing 120 of 34 trials

Recruiting
Phase 2

The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula

Sepsis Induced Myocardial Dysfunction
Dongzhimen Hospital, Beijing80 enrolled1 locationNCT06686355
Recruiting
Phase 2Phase 3

Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS

Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Phase 2

A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.

SepsisAcute Kidney Injury
AstraZeneca124 enrolled71 locationsNCT07215702
Recruiting
Phase 2

Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia

Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+1 more
Todd C. Lee MD MPH FIDSA60 enrolled5 locationsNCT04886284
Recruiting
Phase 2

Efficacy and Safety of YD0743 Treatment for Sepsis-Associated ARDS

Sepsis
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.309 enrolled1 locationNCT07413094
Recruiting
Phase 2Phase 3

A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women

Neonatal SepsisPneumoniaInfections+6 more
Minervax ApS338 enrolled6 locationsNCT06592586
Recruiting
Phase 2Phase 3

A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation

Acute Respiratory Distress Syndrome (ARDS)Acute Lung Injury(ALI)Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
Shanghai University of Traditional Chinese Medicine60 enrolled1 locationNCT07342205
Not Yet Recruiting
Phase 2

MEGA-dose aSCORbatE for Sepsis 2.0 (MEGASCORES 2.0) – a phase Ib multi-centre open-label randomised controlled trial to determine the feasibility and effectiveness of mega-dose sodium ascorbate in adults with septic shock

Sepsis
The Florey Institute50 enrolled1 locationACTRN12625001401448
Recruiting
Phase 2

Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial

Sepsis
University of Minnesota220 enrolled10 locationsNCT05758246
Recruiting
Phase 2

MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial

Sepsis
Mayo Clinic308 enrolled1 locationNCT06319248
Recruiting
Phase 2

Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis

SepsisSeptic ShockPeritonitis
RWTH Aachen University200 enrolled20 locationsNCT03334006
Recruiting
Phase 1Phase 2

Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis

Sepsis
CHA University102 enrolled2 locationsNCT05136560
Recruiting
Phase 2

Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy

Sepsis, Severe
Artcline GmbH142 enrolled20 locationsNCT05442710
Recruiting
Phase 2

An Acupuncture Study for People At High Risk for Sepsis

Sepsis
Memorial Sloan Kettering Cancer Center78 enrolled1 locationNCT06344819
Recruiting
Phase 2

Effects of Paroxetine on Cardiovascular Function in Septic Patients

SepsisSeptic Shock
Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude92 enrolled2 locationsNCT05725837
Recruiting
Phase 2

Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock

SepsisPathologic ProcessesInfections+4 more
Ottawa Hospital Research Institute296 enrolled2 locationsNCT05969275
Recruiting
Phase 2Phase 3

Metformin and Lactoferrin in Sepsis in Icu

Sepsis
Tanta University60 enrolled1 locationNCT06181422
Recruiting
Phase 2Phase 3

The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia

SepsisThrombocytopenia
Ruilan Wang200 enrolled1 locationNCT02707497
Recruiting
Phase 2

Efficacy and Safety of Kukoamine B Mesilate in Sepsis Patients

Sepsis
Tianjin Chasesun Pharmaceutical Co., LTD424 enrolled1 locationNCT04803955
Recruiting
Phase 2

Assessing the Efficacy of Treatment with Vitamin C and Hydrocortisone in Children Admitted to Intensive Care Unit with Septic Shock.

SepsisSeptic Shock
The University of Queensland384 enrolled15 locationsACTRN12621000247875