Phase 2 Sepsis Clinical Trials
37 recruitingPhase 2
What is a Phase 2 trial?
Phase 2 trials evaluate whether a treatment works for a specific condition and further assess its safety. These studies typically enroll several hundred participants and provide preliminary data on effectiveness.
Showing 1–20 of 37 trials
Recruiting
Phase 2
Prospective, Randomized Trial of Personalized Medicine With Pentaglobin® After Surgical Infectious Source Control in Patients With Peritonitis
SepsisSeptic ShockPeritonitis
RWTH Aachen University200 enrolled20 locationsNCT03334006
Recruiting
Phase 1Phase 2
Labile Iron Removal by Adding the Iron Chelator MEX-CD1 to Dialysate in Sepsis-Associated Acute Kidney Injury
SepsisAcute Kidney Injury
Centre Hospitalier Universitaire de Nīmes14 enrolled2 locationsNCT07236463
Recruiting
Phase 2
Adjunctive Fludrocortisone in Septic Shock
SepsisSeptic ShockSepsis and septic shock+2 more
Chinese University of Hong Kong32 enrolled5 locationsNCT07451886
Recruiting
Phase 2
Combination Cefazolin With Ertapenem for Methicillin-susceptible Staphylococcus Aureus Bacteremia
Staphylococcus Aureus BacteremiaStaphylococcus Aureus EndocarditisStaphylococcus Aureus Septicemia+1 more
Todd C. Lee MD MPH FIDSA60 enrolled6 locationsNCT04886284
Recruiting
Phase 2
Corticosteroids in Hyperinflammatory Phenotype of Critical Illness
SepsisAcute Respiratory Distress Syndrome
Bin Du150 enrolled1 locationNCT07511582
Recruiting
Phase 2
An Acupuncture Study for People At High Risk for Sepsis
Sepsis
Memorial Sloan Kettering Cancer Center78 enrolled1 locationNCT06344819
Recruiting
Phase 2
MID-STEP (MIDodrine for Sepsis Treatment and Early vasoPressor Weaning) Trial
SepsisLow blood pressure
Mayo Clinic308 enrolled5 locationsNCT06319248
Recruiting
Phase 2
A Study to Investigate the Efficacy, Safety, and Tolerability of AZD4144in Participants With Sepsis-associated Acute Kidney Injury.
SepsisAcute Kidney Injury
AstraZeneca124 enrolled71 locationsNCT07215702
Recruiting
Phase 2
The Treatment of Sepsis Induced Myocardial Dysfunction With Yiqilishui Formula
Sepsis Induced Myocardial Dysfunction
Dongzhimen Hospital, Beijing80 enrolled1 locationNCT06686355
Recruiting
Phase 2Phase 3
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Phase 2
Efficacy and Safety of YD0743 Treatment for Sepsis-Associated ARDS
Sepsis
Shanghai Yidian Pharmaceutical Technology Development Co., Ltd.309 enrolled1 locationNCT07413094
Recruiting
Phase 2Phase 3
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women
Neonatal SepsisPneumoniaInfections+6 more
Minervax ApS338 enrolled6 locationsNCT06592586
Recruiting
Phase 2Phase 3
A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation
Acute Respiratory Distress Syndrome (ARDS)Acute Lung Injury(ALI)Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
Shanghai University of Traditional Chinese Medicine60 enrolled1 locationNCT07342205
Not Yet Recruiting
Phase 2
MEGA-dose aSCORbatE for Sepsis 2.0 (MEGASCORES 2.0) – a phase Ib multi-centre open-label randomised controlled trial to determine the feasibility and effectiveness of mega-dose sodium ascorbate in adults with septic shock
Sepsis
The Florey Institute50 enrolled1 locationACTRN12625001401448
Recruiting
Phase 2
Senolytics To slOw Progression of Sepsis (STOP-Sepsis) Trial
-Acute infectionSepsisOrgan Failure
University of Minnesota220 enrolled10 locationsNCT05758246
Recruiting
Phase 1Phase 2
Safety and Efficacy of Early Administration of Dexamethasone in High-risk Sepsis
Sepsis
CHA University102 enrolled2 locationsNCT05136560
Recruiting
Phase 2
Recovery From Acute Immune Failure in Septic Shock by Immune Cell Extracorporeal Therapy
Sepsis, Severe
Artcline GmbH142 enrolled20 locationsNCT05442710
Recruiting
Phase 2
Effects of Paroxetine on Cardiovascular Function in Septic Patients
SepsisSeptic Shock
Universidade do Extremo Sul Catarinense - Unidade Academica de Ciecias da Saude92 enrolled2 locationsNCT05725837
Recruiting
Phase 2
Umbilical Mesenchymal Stromal Cells as Cellular Immunotherapy for Septic Shock
SepsisPathologic ProcessesInfections+4 more
Ottawa Hospital Research Institute296 enrolled2 locationsNCT05969275
Recruiting
Phase 2Phase 3
Metformin and Lactoferrin in Sepsis in Icu
Sepsis
Tanta University60 enrolled1 locationNCT06181422