Phase 3 Sepsis Clinical Trials
17 recruitingPhase 3
What is a Phase 3 trial?
Phase 3 trials compare the new treatment against the current standard of care in large groups, often hundreds to thousands of participants. Successful Phase 3 results are typically required for regulatory approval.
Showing 1–17 of 17 trials
Recruiting
Phase 2Phase 3
Targeted Reversal of Inflammation in Pediatric Sepsis-induced MODS
Pediatric Sepsis-induced Multiple Organ Dysfunction Syndrome (MODS)
Nationwide Children's Hospital500 enrolled32 locationsNCT05267821
Recruiting
Phase 3
Early Vasopressors in Sepsis
Sepsis
NHS Greater Glasgow and Clyde1,006 enrolled25 locationsNCT05179499
Recruiting
Phase 2Phase 3
A Follow-up Trial of GBS-NN/NN2 Vaccine in Healthy Pregnant Women
Neonatal SepsisPneumoniaInfections+6 more
Minervax ApS338 enrolled6 locationsNCT06592586
Recruiting
Phase 2Phase 3
A Study on the Treatment of Patients With Acute Lung Injury Caused by Sepsis Through Microbiota Transplantation
Acute Respiratory Distress Syndrome (ARDS)Acute Lung Injury(ALI)Sepsis Related Acute Lung Injury/Acute Respiratory Distress Syndrome
Shanghai University of Traditional Chinese Medicine60 enrolled1 locationNCT07342205
Recruiting
Phase 3
Early Tranexamic Acid and Modulating the Inflammatory Response in Sepsis
Sepsis
Assiut University80 enrolled1 locationNCT04910464
Recruiting
Phase 3
Limited Versus Extended Trophic Feeding (LET-FEED) Trial
SepsisMortalityLength of Stay
University of Washington350 enrolled6 locationsNCT06893939
Recruiting
Phase 3
A Phase III, Open Label, Randomized, Controlled Study of VBI-S in the Treatment of Hypovolemia in Patients With Septic Shock (VBI-S-02)
SepsisSeptic ShockHypovolemia
Vivacelle Bio46 enrolled6 locationsNCT06072430
Recruiting
Phase 2Phase 3
Metformin and Lactoferrin in Sepsis in Icu
Sepsis
Tanta University60 enrolled1 locationNCT06181422
Recruiting
Phase 2Phase 3
The Effect of REcombinant Human Thrombopoietin (rhTPO) on Sepsis Patients With aCUte Severe thrombocytopEnia
SepsisThrombocytopenia
Ruilan Wang200 enrolled1 locationNCT02707497
Recruiting
Phase 3
Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit
SepsisSeptic Shock
Assistance Publique - Hôpitaux de Paris600 enrolled2 locationsNCT05565222
Completed
Phase 2Phase 3
Abdominal Functional Electrical Stimulation To Assist Ventilator Weaning In Critically Ill Patients
Traumatic Brain InjurySepsisStroke+1 more
Neuroscience Research Australia20 enrolled1 locationACTRN12617001180303
Recruiting
Phase 3
Intravenous pentoxifylline as adjunct therapy to improve long-term disability in preterm infants
Late-onset sepsis (LOS)Preterm infantsNecrotising enterocolitis (NEC)+1 more
University of Sydney1,800 enrolled25 locationsACTRN12616000405415
Recruiting
Phase 3
Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial
Severe sepsis
Australian and New Zealand Intensive Care Research Centre1,600 enrolled2 locationsACTRN12608000053325
Recruiting
Phase 3
The use of probiotics to reduce the incidence of sepsis in premature infants.
Late onset sepsis in very premature infants (<32 weeks)
The Royal Women's Foundation Ltd1,100 enrolled1 locationACTRN12607000144415
Recruiting
Phase 3
A prospective double blind randomised clinical trial of 70% ethanol to treat proven or suspected catheter related sepsis in haematology patients.
Proven or suspected central venous catheter sepsis.
Dr Alan Pithie20 enrolled1 locationACTRN12605000489695
Recruiting
Phase 3
Use of ethanol to prevent infection in tunnelled intravenous catheters in haematology patients treated with chemotherapy.
Intravascular tunneled central line catheter related sepsis.
Canterbury District Health Board100 enrolled1 locationACTRN12605000383662
Completed
Phase 3
International neonatal immunotherapy study
Infants with sepsis. Infants being treated with antibiotics are eligible. Infants can be preterm or term.
The University of Sydney5,000 enrolled1 locationACTRN12606000273583