Early Phase 1 SLE Clinical Trials

18 recruitingEarly Phase 1

What is a Early Phase 1 trial?

Early Phase 1 trials are the earliest stage of testing in humans. These small studies focus on how a drug is processed in the body and how it affects the body, often enrolling just a handful of participants to establish initial safety data.

Showing 118 of 18 trials

Recruiting
Early Phase 1

A Study of CC312 for Relapsed/Refractory Autoimmune Diseases

SLE - Systemic Lupus ErythematosusSSc-Systemic SclerosisIIM- Idiopathic Inflammatory Myopathies
CytoCares Inc6 enrolled1 locationNCT07193810
Recruiting
Early Phase 1

Universal Anti-CD70 CAR-T (CHT101) Cell Therapy for Relapsed Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)
The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School15 enrolled1 locationNCT06946485
Recruiting
Early Phase 1

Allogeneic CD19/BCMA CAR-T for B Cell-Related Autoimmune Disease

IgA Nephropathy (IgAN)Autoimmune DiseasesSystemic Sclerosis (SSc)+3 more
The Children's Hospital of Zhejiang University School of Medicine15 enrolled1 locationNCT07507201
Recruiting
Early Phase 1

Exploratory Clinical Study on the Safety and Efficacy of Anti- CD19/BCMA CAR-NK Cell Injection for the Treatment of Refractory Pediatric Rheumatic Diseases

Systemic Lupus Erythematosus (SLE)Rheumatic DiseasesPediatric Rheumatological Condition (i.e., Arthritis, SLE, Kawasaki's Disaese)+1 more
The Children's Hospital of Zhejiang University School of Medicine36 enrolled1 locationNCT07490041
Recruiting
Early Phase 1

Clinical Study on Targeted CD19 or CD19-BCMA CAR-T Therapy for Autoimmune Diseases

SLE (Systemic Lupus)Systemic Sclerosis
Nanjing Bioheng Biotech Co., Ltd.20 enrolled1 locationNCT06548607
Recruiting
Early Phase 1

Ketamine for Shoulder Pain Following Laparoscopic Gastric Sleeve Surgery

Pain ManagementLaparascopic Sleeve Gastrectomy
King Abdullah University Hospital50 enrolled1 locationNCT07429916
Recruiting
Early Phase 1

Clinical Study on Targeted CD19/BCMA CAR-T Therapy for Autoimmune Diseases

SLESystemic SclerosisNMOSD+4 more
Nanjing Bioheng Biotech Co., Ltd.18 enrolled1 locationNCT06775912
Recruiting
Early Phase 1

A Clinical Study Exploring the Safety, Efficacy and Cell Metabolic Dynamics of Universal CD19 / 20 Car-t Cell Injection in Moderate to Severe Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology12 enrolled1 locationNCT07339332
Recruiting
Early Phase 1

Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease

Cognitive ChangeSleepMild Cognitive Impairment+2 more
University of Pittsburgh116 enrolled1 locationNCT05138848
Recruiting
Early Phase 1

Allogeneic UCB-derived CAR-T for SLE

SLE - Systemic Lupus Erythematosus
Chengdu Ucello Biotechnology Co., Ltd.48 enrolled2 locationsNCT07274059
Recruiting
Early Phase 1

Safety and Efficacy of ONT01 in Lupus

Systemic Lupus ErythematosusSLELupus Nephritis (LN)+5 more
Hospital for Special Surgery, New York61 enrolled1 locationNCT07107659
Recruiting
Early Phase 1

A Study of Anti-CD19/BCMA Universal CAR-T Cell Therapy RD06-05 in Patients With Autoimmune Diseases.

SLELN
Nanjing Bioheng Biotech Co., Ltd.84 enrolled1 locationNCT07203404
Recruiting
Early Phase 1

Safety Study of CC312 in Autoimmune Disease Patients

Rheumatoid Arthritis (RA)Autoimmune Hemolytic AnemiaSystemic Lupus Erythematosus (SLE)+3 more
CytoCares Inc18 enrolled1 locationNCT06888960
Recruiting
Early Phase 1

Assessment of OSA in Latin American and Response to Neuromod Therapy

Obstructive Sleep Apnea
Lunair Medical50 enrolled1 locationNCT06762873
Recruiting
Early Phase 1

Social Determinants of Sleep and Obesity

ObesityPhysical InactivitySedentary Behavior+1 more
University of Minnesota90 enrolled1 locationNCT05698693
Recruiting
Early Phase 1

An Exploratory Clinical Study of Anti-CD19 CAR NK Cells in the Treatment of Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)
Changhai Hospital36 enrolled1 locationNCT06010472
Recruiting
Early Phase 1

A Study of LCAR-AIO in Subjects With Relapsed/Refractory Systemic Lupus Erythematosus

Systemic Lupus Erythematosus (SLE)
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology34 enrolled1 locationNCT06653556
Recruiting
Early Phase 1

Time Restricted Eating in Sleep Apnea

Obstructive Sleep ApneaTime Restricted Eating
University of California, San Diego80 enrolled1 locationNCT06047496